Abstract
The strength of the Wisconsin Package (GCG) is that it contains a suite of programs that serve a wide range of sequence analysis needs. A selected number of these programs are described. Each GCG program has extensive modifiers or parameters available. Top-level online help contains a list of all programs and appendices in alphabetical order. Lists of IUPAC standard symbols for amino acids and nucleotides, including ambiguous symbols, can be found in Appendix 2. Program manuals organize the GCG programs into groups of related analyses or functions. The user’s guide contains introductions and overviews that provide an excellent resource for those who are new to GCG. Release notes provide a list of new programs and existing programs with enhancements or bug fixes. To access top-level online help, program manuals, the user’s guide and release notes, simply type genhelp without specifying a program name after the command prompt % (genhelp).
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Suggested Readings
Individual Sequence Analysis
Zuker, M. (1989) On finding all suboptimal foldings of an RNA molecule, Science 244, 48–52.
Pairwise Analysis
Needleman, S. B. and Wunsch, C. D. (1970) A general method applicable to the search for similarities in the amino acid sequence of two proteins, J. Mol. Biol. 48, 443–453.
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© 2003 Springer Science+Business Media New York
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Saisanit, S. (2003). GCG Sequence Analysis. In: Krawetz, S.A., Womble, D.D. (eds) Introduction to Bioinformatics. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-335-4_19
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DOI: https://doi.org/10.1007/978-1-59259-335-4_19
Publisher Name: Humana Press, Totowa, NJ
Print ISBN: 978-1-58829-241-4
Online ISBN: 978-1-59259-335-4
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