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Social Cognition

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Intraoperative Mapping of Cognitive Networks

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Abstract

Social cognition refers to a wide cluster of sociocognitive and socioaffective processes, optimal integration of which allows individuals to efficiently navigate the surrounding, and often fast-changing, social environment. In the neurology literature, it is well known that social cognition impairments have dramatic effects on social adaptability in the context of sudden and neurodevelopmental conditions as well. This is the reason why mapping and preserving social cognition in glioma patients have progressively become an important concern with the aim to give the patients the best opportunities to resume a normal personal and socio-professional life after surgery. In this chapter, after defining social cognition and characterizing its underlying neural networks, the tasks typically used to map and monitor specific aspects of social cognition in the operating theater will be thoroughly described. Next will be reviewed studies showing how beneficial is this intraoperative mapping for the patients’ postoperative recovery. Then, we will develop on the considerable knowledge that has been gained from electrostimulation mapping procedure, especially in the context of mentalizing. Finally, we will provide some guidance on improving the intraoperative mapping of sociocognitive functions.

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References

  1. Baron-Cohen S, Jolliffe T, Mortimore C, Robertson M. Another advanced test of theory of mind: evidence from very high functioning adults with autism or Asperger syndrome. J Child Psychol Psychiatry. 1997;38(7):813–22.

    Article  CAS  Google Scholar 

  2. Brothers L. The social brain: a project for integrating primate behavior and neurophysiology in a new domain. Concepts Neurosci. 1990;1:27–61.

    Google Scholar 

  3. Baron-Cohen S, Ring HA, Bullmore ET, Wheelwright S, Ashwin C, Williams SC. The amygdala theory of autism. Neurosci Biobehav Rev. 2000;24(3):355–64. https://doi.org/10.1016/s0149-7634(00)00011-7.

    Article  CAS  PubMed  Google Scholar 

  4. Green MF, Horan WP, Lee J. Social cognition in schizophrenia. Nat Rev Neurosci. 2015;16(10):620–31. https://doi.org/10.1038/nrn4005.

    Article  CAS  PubMed  Google Scholar 

  5. Penn DL, Sanna LJ, Roberts DL. Social cognition in schizophrenia: an overview. Schizophr Bull. 2008;34(3):408–11. https://doi.org/10.1093/schbul/sbn014.

    Article  PubMed  PubMed Central  Google Scholar 

  6. Adolphs R. The neurobiology of social cognition. Curr Opin Neurobiol. 2001;11(2):231–9. https://doi.org/10.1016/s0959-4388(00)00202-6.

    Article  CAS  PubMed  Google Scholar 

  7. Frith CD, Frith U. Mechanisms of social cognition. Annu Rev Psychol. 2012;63:287–313. https://doi.org/10.1146/annurev-psych-120710-100449.

    Article  PubMed  Google Scholar 

  8. Mar RA. The neural bases of social cognition and story comprehension. Annu Rev Psychol. 2011;62:103–34. https://doi.org/10.1146/annurev-psych-120709-145406.

    Article  PubMed  Google Scholar 

  9. Patterson K, Nestor PJ, Rogers TT. Where do you know what you know? The representation of semantic knowledge in the human brain. Nat Rev Neurosci. 2007;8(12):976–87. https://doi.org/10.1038/nrn2277.

    Article  CAS  PubMed  Google Scholar 

  10. Herbet G, Duffau H. Revisiting the functional anatomy of the human brain: toward a meta-networking theory of cerebral functions. Physiol Rev. 2020;100(3):1181–228. https://doi.org/10.1152/physrev.00033.2019.

    Article  PubMed  Google Scholar 

  11. Schaafsma SM, Pfaff DW, Spunt RP, Adolphs R. Deconstructing and reconstructing theory of mind. Trends Cogn Sci. 2015;19(2):65–72. https://doi.org/10.1016/j.tics.2014.11.007.

    Article  PubMed  Google Scholar 

  12. Keysers C, Gazzola V. Integrating simulation and theory of mind: from self to social cognition. Trends Cogn Sci. 2007;11(5):194–6. https://doi.org/10.1016/j.tics.2007.02.002.

    Article  PubMed  Google Scholar 

  13. Lieberman MD. Social cognitive neuroscience: a review of core processes. Annu Rev Psychol. 2007;58:259–89. https://doi.org/10.1146/annurev.psych.58.110405.085654.

    Article  PubMed  Google Scholar 

  14. Pan J, Zhan L, Hu C, Yang J, Wang C, Gu L, et al. Emotion regulation and complex brain networks: association between expressive suppression and efficiency in the fronto-parietal network and default-mode network. Front Hum Neurosci. 2018;12:70. https://doi.org/10.3389/fnhum.2018.00070.

    Article  PubMed  PubMed Central  Google Scholar 

  15. Wang Y, Metoki A, Alm KH, Olson IR. White matter pathways and social cognition. Neurosci Biobehav Rev. 2018;90:350–70. https://doi.org/10.1016/j.neubiorev.2018.04.015.

    Article  PubMed  PubMed Central  Google Scholar 

  16. Yang DY, Rosenblau G, Keifer C, Pelphrey KA. An integrative neural model of social perception, action observation, and theory of mind. Neurosci Biobehav Rev. 2015;51:263–75. https://doi.org/10.1016/j.neubiorev.2015.01.020.

    Article  PubMed  PubMed Central  Google Scholar 

  17. Grill-Spector K, Weiner KS. The functional architecture of the ventral temporal cortex and its role in categorization. Nat Rev Neurosci. 2014;15(8):536–48. https://doi.org/10.1038/nrn3747.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  18. Grill-Spector K, Weiner KS, Gomez J, Stigliani A, Natu VS. The functional neuroanatomy of face perception: from brain measurements to deep neural networks. Interface Focus. 2018;8(4):20180013. https://doi.org/10.1098/rsfs.2018.0013.

    Article  PubMed  PubMed Central  Google Scholar 

  19. Grill-Spector K, Weiner KS, Kay K, Gomez J. The functional neuroanatomy of human face perception. Annu Rev Vis Sci. 2017;3:167–96. https://doi.org/10.1146/annurev-vision-102016-061214.

    Article  PubMed  PubMed Central  Google Scholar 

  20. Haxby JV, Hoffman EA, Gobbini MI. Human neural systems for face recognition and social communication. Biol Psychiatry. 2002;51(1):59–67. https://doi.org/10.1016/s0006-3223(01)01330-0.

    Article  PubMed  Google Scholar 

  21. Weiner KS, Grill-Spector K. The evolution of face processing networks. Trends Cogn Sci. 2015;19(5):240–1. https://doi.org/10.1016/j.tics.2015.03.010.

    Article  PubMed  PubMed Central  Google Scholar 

  22. Herbet G, Zemmoura I, Duffau H. Functional anatomy of the inferior longitudinal fasciculus: from historical reports to current hypotheses. Front Neuroanat. 2018;12:77. https://doi.org/10.3389/fnana.2018.00077.

    Article  PubMed  PubMed Central  Google Scholar 

  23. Grossi D, Soricelli A, Ponari M, Salvatore E, Quarantelli M, Prinster A, et al. Structural connectivity in a single case of progressive prosopagnosia: the role of the right inferior longitudinal fasciculus. Cortex. 2014;56:111–20. https://doi.org/10.1016/j.cortex.2012.09.010.

    Article  PubMed  Google Scholar 

  24. Thomas C, Avidan G, Humphreys K, Jung KJ, Gao F, Behrmann M. Reduced structural connectivity in ventral visual cortex in congenital prosopagnosia. Nat Neurosci. 2009;12(1):29–31. https://doi.org/10.1038/nn.2224.

    Article  CAS  PubMed  Google Scholar 

  25. Rizzolatti G, Craighero L. The mirror-neuron system. Annu Rev Neurosci. 2004;27:169–92. https://doi.org/10.1146/annurev.neuro.27.070203.144230.

    Article  CAS  PubMed  Google Scholar 

  26. Rizzolatti G, Sinigaglia C. The functional role of the parieto-frontal mirror circuit: interpretations and misinterpretations. Nat Rev Neurosci. 2010;11(4):264–74. https://doi.org/10.1038/nrn2805.

    Article  CAS  PubMed  Google Scholar 

  27. Grossman ED, Battelli L, Pascual-Leone A. Repetitive TMS over posterior STS disrupts perception of biological motion. Vis Res. 2005;45(22):2847–53. https://doi.org/10.1016/j.visres.2005.05.027.

    Article  PubMed  Google Scholar 

  28. Thompson J, Parasuraman R. Attention, biological motion, and action recognition. Neuroimage. 2012;59(1):4–13. https://doi.org/10.1016/j.neuroimage.2011.05.044.

    Article  PubMed  Google Scholar 

  29. Bonini L. The extended mirror neuron network: anatomy, origin, and functions. Neuroscientist. 2017;23(1):56–67. https://doi.org/10.1177/1073858415626400.

    Article  PubMed  Google Scholar 

  30. Bufalari I, Aprile T, Avenanti A, Di Russo F, Aglioti SM. Empathy for pain and touch in the human somatosensory cortex. Cereb Cortex. 2007;17(11):2553–61. https://doi.org/10.1093/cercor/bhl161.

    Article  PubMed  Google Scholar 

  31. Singer T, Critchley HD, Preuschoff K. A common role of insula in feelings, empathy and uncertainty. Trends Cogn Sci. 2009;13(8):334–40. https://doi.org/10.1016/j.tics.2009.05.001.

    Article  PubMed  Google Scholar 

  32. Singer T, Frith C. The painful side of empathy. Nat Neurosci. 2005;8(7):845–6. https://doi.org/10.1038/nn0705-845.

    Article  CAS  PubMed  Google Scholar 

  33. Iacoboni M, Dapretto M. The mirror neuron system and the consequences of its dysfunction. Nat Rev Neurosci. 2006;7(12):942–51. https://doi.org/10.1038/nrn2024.

    Article  CAS  PubMed  Google Scholar 

  34. Premack D, Woodruff G. Does a chimpanzee have a theory of mind. Behav Brain Sci. 1978;1(4):515–26. https://doi.org/10.1017/S0140525X00076512.

    Article  Google Scholar 

  35. Amodio DM, Frith CD. Meeting of minds: the medial frontal cortex and social cognition. Nat Rev Neurosci. 2006;7(4):268–77. https://doi.org/10.1038/nrn1884.

    Article  CAS  PubMed  Google Scholar 

  36. Carrington SJ, Bailey AJ. Are there theory of mind regions in the brain? A review of the neuroimaging literature. Hum Brain Mapp. 2009;30(8):2313–35. https://doi.org/10.1002/hbm.20671.

    Article  PubMed  Google Scholar 

  37. Schurz M, Radua J, Aichhorn M, Richlan F, Perner J. Fractionating theory of mind: a meta-analysis of functional brain imaging studies. Neurosci Biobehav Rev. 2014;42:9–34. https://doi.org/10.1016/j.neubiorev.2014.01.009.

    Article  PubMed  Google Scholar 

  38. Frith U, Frith CD. Development and neurophysiology of mentalizing. Philos Trans R Soc Lond Ser B Biol Sci. 2003;358(1431):459–73. https://doi.org/10.1098/rstb.2002.1218.

    Article  Google Scholar 

  39. Van Overwalle F, Baetens K. Understanding others’ actions and goals by mirror and mentalizing systems: a meta-analysis. Neuroimage. 2009;48(3):564–84. https://doi.org/10.1016/j.neuroimage.2009.06.009.

    Article  PubMed  Google Scholar 

  40. Grosse Wiesmann C, Schreiber J, Singer T, Steinbeis N, Friederici AD. White matter maturation is associated with the emergence of Theory of Mind in early childhood. Nat Commun. 2017;8:14692. https://doi.org/10.1038/ncomms14692.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  41. Herbet G, Lafargue G, de Champfleur NM, Moritz-Gasser S, le Bars E, Bonnetblanc F, et al. Disrupting posterior cingulate connectivity disconnects consciousness from the external environment. Neuropsychologia. 2014b;56:239–44. https://doi.org/10.1016/j.neuropsychologia.2014.01.020.

    Article  PubMed  Google Scholar 

  42. Herbet G, Lafargue G, Moritz-Gasser S, Menjot de Champfleur N, Costi E, Bonnetblanc F, et al. A disconnection account of subjective empathy impairments in diffuse low-grade glioma patients. Neuropsychologia. 2015b;70:165–76. https://doi.org/10.1016/j.neuropsychologia.2015.02.015.

    Article  PubMed  Google Scholar 

  43. Nakajima R, Yordanova YN, Duffau H, Herbet G. Neuropsychological evidence for the crucial role of the right arcuate fasciculus in the face-based mentalizing network: a disconnection analysis. Neuropsychologia. 2018b;115:179–87. https://doi.org/10.1016/j.neuropsychologia.2018.01.024.

    Article  PubMed  Google Scholar 

  44. Wang Y, Olson IR. The original social network: white matter and social cognition. Trends Cogn Sci. 2018;22(6):504–16. https://doi.org/10.1016/j.tics.2018.03.005.

    Article  PubMed  PubMed Central  Google Scholar 

  45. Yordanova YN, Duffau H, Herbet G. Neural pathways subserving face-based mentalizing. Brain Struct Funct. 2017;222(7):3087–105. https://doi.org/10.1007/s00429-017-1388-0.

    Article  PubMed  Google Scholar 

  46. Pertz M, Okoniewski A, Schlegel U, Thoma P. Impairment of sociocognitive functions in patients with brain tumours. Neurosci Biobehav Rev. 2020;108:370–92. https://doi.org/10.1016/j.neubiorev.2019.11.018.

    Article  PubMed  Google Scholar 

  47. Campanella F, Fabbro F, Ius T, Shallice T, Skrap M. Acute effects of surgery on emotion and personality of brain tumor patients: surgery impact, histological aspects, and recovery. Neuro Oncol. 2015;17(8):1121–31. https://doi.org/10.1093/neuonc/nov065.

    Article  PubMed  PubMed Central  Google Scholar 

  48. Goebel S, Mehdorn HM, Wiesner CD. Social cognition in patients with intracranial tumors: do we forget something in the routine neuropsychological examination? J Neurooncol. 2018;140(3):687–96. https://doi.org/10.1007/s11060-018-3000-8.

    Article  PubMed  Google Scholar 

  49. Herbet G, Lafargue G, Bonnetblanc F, Moritz-Gasser S, Duffau H. Is the right frontal cortex really crucial in the mentalizing network? A longitudinal study in patients with a slow-growing lesion. Cortex. 2013;49(10):2711–27. https://doi.org/10.1016/j.cortex.2013.08.003.

    Article  PubMed  Google Scholar 

  50. Herbet G, Lafargue G, Moritz-Gasser S, Bonnetblanc F, Duffau H. Interfering with the neural activity of mirror-related frontal areas impairs mentalistic inferences. Brain Struct Funct. 2015a;220(4):2159–69. https://doi.org/10.1007/s00429-014-0777-x.

    Article  PubMed  Google Scholar 

  51. Nakajima R, Kinoshita M, Okita H, Yahata T, Matsui M, Nakada M. Neural networks mediating high-level mentalizing in patients with right cerebral hemispheric gliomas. Front Behav Neurosci. 2018a;12:33. https://doi.org/10.3389/fnbeh.2018.00033.

    Article  PubMed  PubMed Central  Google Scholar 

  52. Herbet G, Lafargue G, Bonnetblanc F, Moritz-Gasser S, Menjot de Champfleur N, Duffau H. Inferring a dual-stream model of mentalizing from associative white matter fibres disconnection. Brain. 2014a;137(Pt 3):944–59. https://doi.org/10.1093/brain/awt370.

    Article  PubMed  Google Scholar 

  53. Abu-Akel A, Shamay-Tsoory S. Neuroanatomical and neurochemical bases of theory of mind. Neuropsychologia. 2011;49(11):2971–84.

    Google Scholar 

  54. Bates E, Wilson SM, Saygin AP, Dick F, Sereno MI, Knight RT, et al. Voxel-based lesion-symptom mapping. Nat Neurosci. 2003;6(5):448–50. https://doi.org/10.1038/nn1050.

    Article  CAS  PubMed  Google Scholar 

  55. Thiebaut de Schotten M, Urbanski M, Valabregue R, Bayle DJ, Volle E. Subdivision of the occipital lobes: an anatomical and functional MRI connectivity study. Cortex. 2014;56:121–37. https://doi.org/10.1016/j.cortex.2012.12.007.

    Article  PubMed  Google Scholar 

  56. Baron-Cohen S, Wheelwright S. The empathy quotient: an investigation of adults with Asperger syndrome or high functioning autism, and normal sex differences. J Autism Dev Disord. 2004;34(2):163–75. https://doi.org/10.1023/b:jadd.0000022607.19833.00.

    Article  PubMed  Google Scholar 

  57. Lawrence EJ, Shaw P, Baker D, Baron-Cohen S, David AS. Measuring empathy: reliability and validity of the Empathy Quotient. Psychol Med. 2004;34(5):911–9.

    Article  CAS  Google Scholar 

  58. Campanella F, Shallice T, Ius T, Fabbro F, Skrap M. Impact of brain tumour location on emotion and personality: a voxel-based lesion-symptom mapping study on mentalization processes. Brain. 2014;137(Pt 9):2532–45. https://doi.org/10.1093/brain/awu183.

    Article  PubMed  Google Scholar 

  59. Giussani C, Pirillo D, Roux FE. Mirror of the soul: a cortical stimulation study on recognition of facial emotions. J Neurosurg. 2010;112(3):520–7. https://doi.org/10.3171/2009.5.JNS081522.

    Article  PubMed  Google Scholar 

  60. Papagno C, Pisoni A, Mattavelli G, Casarotti A, Comi A, Fumagalli F, et al. Specific disgust processing in the left insula: new evidence from direct electrical stimulation. Neuropsychologia. 2016;84:29–35. https://doi.org/10.1016/j.neuropsychologia.2016.01.036.

    Article  PubMed  Google Scholar 

  61. Mandonnet E, Herbet G, Duffau H. Letter: introducing new tasks for intraoperative mapping in awake glioma surgery: clearing the line between patient care and scientific research. Neurosurgery. 2020;86(2):E256–7. https://doi.org/10.1093/neuros/nyz447.

    Article  PubMed  Google Scholar 

  62. Herbet G, Maheu M, Costi E, Lafargue G, Duffau H. Mapping neuroplastic potential in brain-damaged patients. Brain. 2016;139(Pt 3):829–44. https://doi.org/10.1093/brain/awv394.

    Article  PubMed  Google Scholar 

  63. Yordanova YN, Cochereau J, Duffau H, Herbet G. Combining resting state functional MRI with intraoperative cortical stimulation to map the mentalizing network. Neuroimage. 2019;186:628–36. https://doi.org/10.1016/j.neuroimage.2018.11.046.

    Article  PubMed  Google Scholar 

  64. Baron-Cohen S, Wheelwright S, Hill J, Raste Y, Plumb I. The “Reading the Mind in the Eyes” Test revised version: a study with normal adults, and adults with Asperger syndrome or high-functioning autism. J Child Psychol Psychiatry. 2001;42(2):241–51.

    Article  CAS  Google Scholar 

  65. Nakajima R, Kinoshita M, Okita H, Yahata T, Nakada M. Glioma surgery under awake condition can lead to good independence and functional outcome excluding deep sensation and visuospatial cognition. Neurooncol Pract. 2019;6(5):354–63. https://doi.org/10.1093/nop/npy054.

    Article  PubMed  Google Scholar 

  66. Duffau H. Stimulation mapping of white matter tracts to study brain functional connectivity. Nat Rev Neurol. 2015;11(5):255–65. https://doi.org/10.1038/nrneurol.2015.51.

    Article  PubMed  Google Scholar 

  67. Cochereau J, Deverdun J, Herbet G, Charroud C, Boyer A, Moritz-Gasser S, et al. Comparison between resting state fMRI networks and responsive cortical stimulations in glioma patients. Hum Brain Mapp. 2016;37(11):3721–32. https://doi.org/10.1002/hbm.23270.

    Article  PubMed  PubMed Central  Google Scholar 

  68. Rojkova K, Volle E, Urbanski M, Humbert F, Dell’Acqua F, Thiebaut de Schotten M. Atlasing the frontal lobe connections and their variability due to age and education: a spherical deconvolution tractography study. Brain Struct Funct. 2016;221(3):1751–66. https://doi.org/10.1007/s00429-015-1001-3.

    Article  CAS  PubMed  Google Scholar 

  69. Mandonnet E, Herbet G, Moritz-Gasser S, Poisson I, Rheault F, Duffau H. Electrically induced verbal perseveration: a striatal deafferentation model. Neurology. 2019;92(6):e613–21. https://doi.org/10.1212/WNL.0000000000006880.

    Article  PubMed  Google Scholar 

  70. Almairac F, Herbet G, Moritz-Gasser S, de Champfleur NM, Duffau H. The left inferior fronto-occipital fasciculus subserves language semantics: a multilevel lesion study. Brain Struct Funct. 2015;220(4):1983–95. https://doi.org/10.1007/s00429-014-0773-1.

    Article  PubMed  Google Scholar 

  71. Schilbach L, Timmermans B, Reddy V, Costall A, Bente G, Schlicht T, et al. Toward a second-person neuroscience. Behav Brain Sci. 2013;36(4):393–414. https://doi.org/10.1017/S0140525X12000660.

    Article  PubMed  Google Scholar 

  72. Adolphs R. Recognizing emotion from facial expressions: psychological and neurological mechanisms. Behav Cogn Neurosci Rev. 2002;1(1):21–62. https://doi.org/10.1177/1534582302001001003.

    Article  PubMed  Google Scholar 

  73. Nakada M. The handbook of awake surgery. Tokyo: Chugai-igaku; 2019.

    Google Scholar 

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Authors and Affiliations

  1. Department of Occupational Therapy, Faculty of Health Science, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan

    Riho Nakajima

  2. Department of Neurosurgery, Kanazawa University, Kanazawa, Japan

    Masashi Kinoshita & Mitsutoshi Nakada

  3. Department of Neurosurgery, Gui de Chauliac Hospital, Montpellier & Institute of Functional Genomics, University of Montpellier, INSERM, CNRS, Montpellier, France

    Guillaume Herbet

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  1. Riho Nakajima
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  2. Masashi Kinoshita
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  3. Mitsutoshi Nakada
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  4. Guillaume Herbet
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Correspondence to Guillaume Herbet .

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Editors and Affiliations

  1. Department of Neurosurgery, Lariboisière Hospital, Paris Brain Institute (ICM) and Paris University, Paris, France

    Emmanuel Mandonnet

  2. Department of Neurosurgery, Gui de Chauliac Hospital, Montpellier & Institute of Functional Genomics, University of Montpellier, INSERM, CNRS, Montpellier, France

    Guillaume Herbet

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Nakajima, R., Kinoshita, M., Nakada, M., Herbet, G. (2021). Social Cognition. In: Mandonnet, E., Herbet, G. (eds) Intraoperative Mapping of Cognitive Networks. Springer, Cham. https://doi.org/10.1007/978-3-030-75071-8_18

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