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Cerebellar Neurogenesis

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Essentials of Cerebellum and Cerebellar Disorders

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Abstract

The mechanisms of cerebellar neurogenesis have been redefined in the last few years, showing the precise spatio-temporal sequence of neuronal generation from neurochemically heterogeneous pools of progenitors. Here we describe these processes, highlighting the principal strategies used within this system to generate appropriate cell numbers and phenotypes.

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Acknowledgements

KL’s research is funded by a grant from Ricerca Fondo per l’Incentivazione della Ricerca di Base (n. RBFR10A01S). GGC’s cerebellar research is funded by the Italian Telethon Foundation.

Author information

Authors and Affiliations

  1. Department of Neuroscience Rita Levi Montalcini, University of Turin, Torino, Italy

    Ketty Leto

  2. Neuroscience Institute Cavalieri-Ottolenghi, University of Turin, Regione Gonzole 10, Orbassano, 10043, Torino, Italy

    Ketty Leto

  3. Cumming School of Medicine, Department of Cell Biology & Anatomy, Genes and Development Research Group, and Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, 3330 Hospital Drive NW, Calgary, Alberta, T2N 4N1, Canada

    Richard Hawkes

  4. Università Vita-Salute San Raffaele, Milan, Italy

    G. Giacomo Consalez

  5. Division of Neuroscience, San Raffaele Scientific Institute, Via Olgettina 60, 20132, Milan, Italy

    G. Giacomo Consalez

Authors
  1. Ketty Leto
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  2. Richard Hawkes
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  3. G. Giacomo Consalez
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Corresponding author

Correspondence to G. Giacomo Consalez .

Editor information

Editors and Affiliations

  1. Molecular and Cellular Neuroscience Department, The Scripps Research Institute, La Jolla, California, USA

    Donna L. Gruol

  2. Department of Integrative Physiology, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan

    Noriyuki Koibuchi

  3. FNRS, ULB-Erasme, Bruxelles, Belgium

    Mario Manto

  4. Clinical Translational Research, Santa Lucia Foundation, Rome, Italy

    Marco Molinari

  5. Ataxia Unit, Cognitive Behavioral Neurology Unit, Laboratory for Neuroanatomy and Cerebellar Neurobiology, Department of Neurology Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA

    Jeremy D. Schmahmann

  6. Department of Neurobiology, Zhejiang University School of Medicine, Hangzhou, China

    Ying Shen

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Leto, K., Hawkes, R., Consalez, G.G. (2016). Cerebellar Neurogenesis. In: Gruol, D., Koibuchi, N., Manto, M., Molinari, M., Schmahmann, J., Shen, Y. (eds) Essentials of Cerebellum and Cerebellar Disorders. Springer, Cham. https://doi.org/10.1007/978-3-319-24551-5_13

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