Zusammenfassung
Seit nahezu 20 Jahren werden die Techniken der extrakorporalen Befruchtung erfolgreich angewandt. Hierbei findet die Zeugung, die in vivo nicht erfolgen kann, außerhalb des Körpers (in vitro) statt. Voraussetzung hierfür ist das Zusammenbringen einer reifen Oozyte, die die 1. Reifeteilung vollzogen hat (Metaphase II), und eines befruchtungsfähigen Spermiums unter optimalen Bedingungen.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Similar content being viewed by others
Literatur
Asch RH (1991) Uterine versus tubal embryo transfer in human. Comparative analysis of implantation, pregnancy and live birth rates. Ann NY Acad Sci 626: 461
Behre HM, Yeung CH, Nieschlag E (1996) Diagnostik der Infertilität und des Hypogonadis-mus. In: Nieschlag E, Behre HM (Hrsg) Andrologie. Grundlagen und Klinik der repro-duktiven Gesundheit des Mannes. Springer, Berlin Heidelberg New York Tokio, S 91–117
Burgus R, Butcher M, Amoss M et al. (1972) Primary structure of ovine hypothalamic lutei-nizing hormone releasing factor (LRF). Proc Natl Acad Sci USA 69: 278–282
Chang MC (1959) Fertilization of rabbit ova in vitro. Nature 184: 466
Chetkowski RJ, Kruse LR, Nass TE (1989) Improved pregnancy outcome with the addition of leuproline acetate to gonadotropins for in-vitro fertilization. Fertil Steril 52: 250–255
Diedrich K (1987) Unerwünschte Kinderlosigkeit. In: Martius D (Hrsg) Differentialdiagnose in Geburtshilfe und Gynäkologie, Bd 2 Gynäkologie. Thieme, Stuttgart, S 84–100
Diedrich K (1990) Neue Wege in Diagnostik und Therapie der Sterilität. Enke, Stuttgart
Diedrich K, Wildt L, Diedrich C, Van der Ven H, Al-Hasani S, Lehmann F, Krebs D (1985) Ovarielle Stimulation für die In-vitro-Fertilisation. Fertilität 1: 26
Diedrich K, Van der Ven H, Al-Hasani S, Krebs D (1988) Ovarian stimulation for in vitro fertilization. Hum Reprod 3: 39–44
Diedrich K, Al-Hasani S, Van der Ven H, Diedrich C, Krebs D (1990) In-vitro-Fertilisation und Embryotransfer. In: Diedrich K (Hrsg) Neue Wege in Diagnostik und Therapie der Sterilität. Enke, Stuttgart, S 169–195
Diedrich K, Diedrich C, Santos E et al. (1994) Suppression of the endogenous luteinizing hormone surge by the gonadotropin-releasing hormone antagonist Cetrorelix during ovarian stimulation. Hum Reprod 9: 788–791
Diedrich K, Felberbaum R, Küpker W, Al-Hasani S (1995) New approaches to male infertility: IVF and microinjection. Int J Androl 18: 78
Edwards RG (1981) Test tube babies. Nature 293: 253
Edwards RG, Steptoe PC (1974) Control of human ovulation, fertilization and implantation. Proc R Soc Med 67: 932
Edwards RG, Lobo RA, Bouchard P (1996) Time to revolutionise ovarian stimulation. Hum Reprod 11: 917–919
Eshkol A, Lunenfeld B (1967) Purification and separation of follicle stimulation hormone (FSH) and luteinizing hormone (LH) from human menopausal gonadotropine (HMG). Effects of a biologically apparently pure FSH preparation on ovaries and uteri of intact immature mice. Acta Endocrinol Copenh 54: 91–95
Feichtinger W (1991) Environmental factors and fertility. Hum Reprod 6: 1170–1175
Felberbaum R, Diedrich K (1996) Klinischer Einsatz der GnRH-Analoga im Rahmen der Sterilitätstherapie: Agonisten und Antagonisten. Gynäkologe 6: 420–432
Felberbaum RE, Reissmann T, Küpker W, Bauer 0, Al-Hasani S, Diedrich C, Diedrich K (1995) Fertilization rate and amount of human menopausal gonadotropin needed in controlled ovarian hyperstimulation under low-dose gonadotropin releasing hormone antagonist treatment. Hum Reprod 10: 8
Felberbaum R, Reissmann T, Küpker Wet al. (1996) Hormone profiles under ovarian stimulation with human menopausal gonadotropin (hMG) and concomitant administration of the gonadotropin-releasing hormone (GnRH)-antagonist Cetrorelix at different dosages. J Assist Reprod Genet 13: 216
Fisch B, Avrech OM, Pinkas H, Neri A, Rufas O, Ovadia J (1995) Superovulation before IVF by recombinant versus urinary human FSH (combined with a long GnRH analog protocol): a comparative study. J Assist Reprod Genet 12: 26–31
Fleming R, Haxton MJ, Hamilton MPR, McCune GS, Black WP, McNaughton MC, Coutts JRT (1985) Successful treatment of infertile women with oligomenorrhea using a combination of an LHRH agonist and exogenous gonadotropins. Br J Obstet Gynecol 92: 369–373
Gembruch U, Diedrich K, Al-Hasani S, Welker B, Wahode J, Van der Ven H, Krebs D (1988) Transvaginale-ultraschallkontrollierte Follikelpunktion. Geburtshilfe Frauenheilkd 48: 617–624
Gemzell C (1969) Treatment of female and male sterility with human gonadotropins. Acta Obstet Gynecol Scand 48 [Suppl 11: 17–30
Gerhard I, Runnebaum B (1992) Schadstoffe und Fertilitätsstörungen–Genußgifte. Geburtshilfe Frauenheilkd 52: 509–515
Gordon K, Hodgen GD (1993) Evolving role of Gonadotropin releasing hormone antagonists. Trends Endocrinol Metab 3: 259
Grunwald K, Rabe T, Runnebaum B (1997) Physiology of the menstrual cycle. In: Rabe T, Diedrich K, Runnebaum B (eds) Manual of assisted reproduction. Springer, Berlin Heidelberg New York Tokyo, pp 22–77
Hammerstein J (1969) Mode of action of clomiphene. Inhibitory effect of clomiphene-citrat on the formation of progesterone from acetate-1–14C by human corpus luteum slices in vitro. Acta Endocrinol Copenh 60: 635–644
Heape W (1891) Preliminary note on the transplantation and growth of mammalian ova within a uterine foster mother. Proc R Soc 48: 457–458
Hillier SG (1994) Curent concepts of the role of FSH and LH in folliculogenesis. Hum Re-prod 9: 188–191
Homburg R, Eshel A, Abdalla HI et al. (1988) Growth hormon facilitates ovulation induction by gonadotropins. Clin Endocrinol 29: 113
IVF-Register 1996
Keller R, Günther HL, Kaiser P (1992) Embryonenschutzgesetz. Kommentar zum Embryonenschutzgesetz. Kohlhammer, Stuttgart
Klingmüller D, Diedrich K, Sommer L (1993) Effect of the GnRH antagonist Cetrorelix in normal women. Gynecol Endocrinol 7: 2
Knobil E (1980) The neuroendocrine control of the menstrual cycle. Recent Prog Horm Res 36: 53–88
Küpker W, Al-Hasani S, Bauer O, Diedrich K (1994) Neue Techniken der assistierten Befruchtung. Fertilität 10: 216–220
Küpker W, Al-Hasani S, Diedrich K (1996) Techniken der assistierten Reproduktion. In: Praxis der Spermatologie. Atlas und Anleitung, 2. Aufl. Springer, Berlin Heidelberg New York Tokio, S 89–113
Lavie P, Kripke DF (1981) Ultradian circa 1.5 hour rhythms: a multioscillatory system. Life Sci 29: 2445
Lenz S, Lauritzen SJG, Kjellow M (1981) Collection of human oocytes for in vitro fertilization by ultrasonically guided follicular puncture. Lancet 1: 1163
Leyendecker G, Wildt L, Hansmann M (1980) Pregnancies following chronic intermittent (pulsatile) administration of GnRH by means of a portable pump (Zyklomat) - a new approach to the treatment of infertility in hypothalamic amenorrhea. J Clin Endocrinol Metab 51: 1214
Lopata A (1983) Concepts in human in vitro fertilization and embryo transfer. Fertil Steril 40: 289–301
Lopata A, Johnson IWH, Leeton JF, Muchniki D, McTalbot J, Wood C (1974) Collection of human oocytes at laparoscopy and laparotomy. Fertil Steril 25: 1030–1038
Loumaye E (1990) The control of endogenous secretion of LH by gonadotropin-releasing hormone agonists during ovarian hyperstimulation for in-vitro fertilization and embryo transfer. Hum Reprod 5: 557–576
Ludwig G, Frick J, Rovan E (1996) Praxis der Spermatologie. Springer, Berlin Heidelberg New York Tokio
Lunenfeld B, Eshkol A (1969) Immunology of follicle-stimulating hormone and luteinizing hormone. Vitam Horm 27: 131–197
March CM (1993) Ovulation induction. J Reprod Med 38: 335–346
Menken I, Rock J (1948) In-vitro fertilization and cleavage of human ovarian eggs. Am J Obstet Gynecol 55: 440–451
Pincus G, Enzmann EV (1934) Can mammalian eggs undergo normal development in vitro? Proc Natl Acad Sci 20: 121–122
Rabe T, Diedrich K, Eberhardt J, Küpker W (1997) In vitro fertilization. In: Rabe T, Diedrich K, Runnebaum B (eds) Manual of assisted reproduction. Springer, Berlin Heidelberg New York Tokyo, pp 252–311
Schenk SL (1880) Das Säugethierei künstlich befruchtet ausserhalb des Mutterthiers. Mitt Embryo Inst Wien, Bd 9
Schmutzler RK, Diedrich K (1990) Basic and clinical aspects of GnRH-agonists in reproduction. Int J Gynec Obstet 32: 311–324
Siebzehnrübel E, Todorow S, Spitzer M, Neuwinger J, Wildt L, Lang N (1993) Die Erweiterung des Konzepts der extrakorporalen Befruchtung durch die Kryokonservierung imprägnierter Eizellen. Geburtshilfe Frauenheilkd 53: 359–365
Smitz J, Devroey P, Braeckmans P et al. (1987) Management of failed cycles in an IVF/GIFT programme with the combination of a GnRH analog and HMG. Hum Reprod 2: 309–314
Smitz J, Devroey P, Bourgain C et al. (1988) Luteal supplementation regimes after combined GnRH-agonist/HMG superovulation. J Reprod Fertil Abstr Ser 2: 18
Smitz J, Ron-El R, Tarlatzis BC (1992) The use of gonadotropin releasing hormone agonists for in-vitro fertilization and other assisted procreation techniques. Experience from three centers. Hum Reprod 2: 309–314
Stanger JD, Yovich JL (1985) Reduced in-vitro fertilization of human oocytes from patients with raised basal luteinizing hormon levels during the follicular phase.Br J Obstet Gynecol 92: 385–393
Stauber M (1993) Psychosomatik der ungewollten Kinderlosigkeit. BMV, Berlin
Steptoe PC, Edwards RG (1978) Birth after reimplantation of a human embryo. Lancet 11: 366
Tan SL, Kingsland C, Campbell S (1993) The use of buserelin in in vitro fertilization - a comparison between the long and short protocols of administration. Gynecol Endocrinol 4 [Suppl 21: 107
Tanbo T, Dale PO, Kjekhus E, Haug E, Abyholm T (1990) Stimulation with human menopausal gonadotropin versus follicle-stimulating hormone after pituitary suppression in polycystic ovarian syndrome. Fertil Steril 53: 798–803
Tartlatzis BC, Pados G, Bontis J, Lagos S, Grimbizis G, Spanos E, Mantalenakis S (1993) Ovarian stimulation with buserelin/HMG/HCG: prospective randomized study of short versus long protocol. Hum Reprod 8: 807–812
Trounson AO, Leeton JF, Wood C, Webb J, Wood J (1981) Pregnancies in human by fertiliza- tion in vitro and embryo transfer in the controlled ovulatory cycle. Science 212: 681
Van Steirteghem AC, Liu J, Joris H et al. (1993) Higher success rate by intracytoplasmatic sperm injection than by subzonal insemination. Report of a second series of 300 consecutive treatment cycles
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1998 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Diedrich, K., Weiss, J.M., Felberbaum, R. (1998). In-vitro-Fertilisation. In: Diedrich, K. (eds) Weibliche Sterilität. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-58738-2_15
Download citation
DOI: https://doi.org/10.1007/978-3-642-58738-2_15
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-63704-9
Online ISBN: 978-3-642-58738-2
eBook Packages: Springer Book Archive