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Abstract

The bacterial chromosome, while evolving by point mutations in its DNA, is thought to be rather stable with regard to its gross organization. For example, even though the DNAs of Salmonella and Escherichia cross-hybridize only weakly due to divergent sequence evolution (Demerec and New, 1965; Brenner et al., 1969), the genetic maps of the two bacteria are rather similar with respect to the order of functions (Sanderson and Demerec, 1965).

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Starlinger, P., Saedler, H. (1976). IS-Elements in Microorganisms. In: Arber, W., et al. Current Topics in Microbiology and Immunology / Ergebnisse der Microbiologie und Immunitätsforschung. Current Topics in Microbiology and Immunology / Ergebnisse der Microbiologie und Immunitätsforschung, vol 75. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-66530-1_4

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