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Signal Transduction by Growth Factor Receptors

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Cell Cycle and Oncogenes

Abstract

Growth factors are polypeptide hormones that induce replicative DNA synthesis and cell division in their target cells. Like all polypeptide hormones, growth factors initiate their action by binding to specific, high-affinity receptor molecules on the cell surface. Although much has been learned about growth factor-receptor interaction, the molecular mechanisms of action and the in vivo function of growth factors are poorly understood.

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Author information

Authors and Affiliations

  1. Hubrecht Laboratory, Uppsalalaan 8, 3584, Utrecht, The Netherlands

    S. W. de Laat

Authors
  1. W. H. Moolenaar
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  2. A. J. Bierman
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  3. L. H. K. Defize
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  4. B. C. Tilly
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  5. S. W. de Laat
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Editor information

Editors and Affiliations

  1. Naturwissenschaftliche Fakultät III, Biologie und Vorklinische Medizin, Universitätsstraße 31, 8400, Regensburg, Germany

    Widmar Tanner

  2. Physiologisch-Chemisches Institut I, Universität Marburg, Emil-Mannkopff-Straße 1, 3550, Marburg, Germany

    Dieter Gallwitz

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© 1986 Springer-Verlag Berlin Heidelberg

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Moolenaar, W.H., Bierman, A.J., Defize, L.H.K., Tilly, B.C., de Laat, S.W. (1986). Signal Transduction by Growth Factor Receptors. In: Tanner, W., Gallwitz, D. (eds) Cell Cycle and Oncogenes. Colloquium der Gesellschaft für Biologische Chemie 10.–12. April 1986 in Mosbach/Baden, vol 37. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71686-7_17

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  • DOI: https://doi.org/10.1007/978-3-642-71686-7_17

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-71688-1

  • Online ISBN: 978-3-642-71686-7

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