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Multiple Primary Neoplasms

  • Chapter
Influence of Tumor Development on the Host

Part of the book series: Cancer Growth and Progression ((CAGP,volume 3))

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Abstract

Multiple primary neoplasms are those primaries which exhibit a different histology, different location and which are present in the same host (33). They may be present at the same time or occur consecutively. These neoplasms should be considered in light of the relationship between host and neoplastic disease. In the interval between the first to the second primary, the patient may be looking disease-free because the host is free of neoplastic disease if we do not consider the metabolic condition of the host. The field of multiple primary neoplasms was extensively reviewed by Severi (1974). Multiple primary tumors can be seen as a malignant predisposition of more than one host tissue (167, 159). Also triple and quadruple primaries have been observed. There are also, less well proven, multiple primary tumors of the same tissue, e.g. of intestinal mucosa. These are known as multicentric tumors. Multiple primaries underly the tumor-host interaction. One primary neoplasm may even metastasize to other primary or its metastasis (7, 214, 68, 212, 20, 127).

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References

  1. Abramson DH, Ronner HJ, Ellsworth RM: Second tumors in nonirradiated bilateral retinoblastoma. Am J. Ophthalmol 87(5):624–7, 1979

    PubMed  CAS  Google Scholar 

  2. Abramson DH, Rodriguez-Sains RS, Rubman R: B-K mole syndrome. Cutaneous and ocular malignant melanoma. Arch Ophthalmol 98(8):1397–9, 1980

    PubMed  CAS  Google Scholar 

  3. Adami HO, Krusemo UB, Bergkvist L, et al: On the agedependent association between cancer of the breast and of the endometrium. A nationwide cohort study. Br J Cancer 55(1):77–80, 1987

    PubMed  CAS  Google Scholar 

  4. Aeschlimann A, Mall T, Radu E, Gratzl O: Benign intra- and extracranial meningioma. Eur Neurol 25(2):125–9, 1986

    PubMed  CAS  Google Scholar 

  5. Allen BV, Wannop CC, Wright IM: Multicentric lymphosarcoma with lymphoblastic leukaemia in a young horse, Vet Rec 115(6):130–1, 1984

    PubMed  CAS  Google Scholar 

  6. Allevato Ma, Donatti LB, Ines Suarez T, Stringa SG: Kaposi’s angiosarcoma developing in a patient with a renal transplant. Med Cutan Ibero Lat Am 12(2):137–44, 1984

    PubMed  CAS  Google Scholar 

  7. Anichkov NM, Zus’ BV, Samova NV: Metastasis of one tumor into another in multiple primary neoplasms. Arkh Patol 47 (1):60–3, 1985

    PubMed  CAS  Google Scholar 

  8. Armitage JO, Dick Fr, Gosken JA, et al:Second lymphoid malignant neoplasms occurring in patients treated for Hodgkin’s disease. Arch Intern Med 143(3):445–50, 1983

    PubMed  CAS  Google Scholar 

  9. Asano S, Shimoe S, Sagawa S: Spontaneous maturation in the metastatic region of a bilateral testicular germ cell tumor. Urol Int 39(6):361–5, 1984

    PubMed  CAS  Google Scholar 

  10. Avsare SS, Prabhu SR, Vengsarkar US, et al: Von Recklinghasen’s disease with a malignant meningeal, cerebral and optic nerve tumour and bilateral vagal schwannomas. Possible mesenchymal histogenesis on light and electron microscopy. J Neurol Sci 54(3):427–43, 1982

    PubMed  CAS  Google Scholar 

  11. Ayani N, Shea JJ: Asymptomatic schwannoma of the cochlear nerve. Arch Otolaryngol 108(8):501–3, 1982

    PubMed  CAS  Google Scholar 

  12. Bajardi F: Neural proliferation as a concomitant finding in neoplasias and benign ectopias of the uterine cervix. Zentralbl Gynakol 107(4):227–36, 1985

    PubMed  CAS  Google Scholar 

  13. Balsa RE, Ingratta SM, Galeano FA, et al: Basal cell nevus syndrome. Presentation of 2 cases, 1 associated with medulloblastoma. Med Cutan Ibero Lat Am 13(1):5–11, 1985

    PubMed  CAS  Google Scholar 

  14. Banse-Kupin L, Morales A, Barlow M: Torre’s syndrome: report of two cases and review of the literature. J Am Acad Dermatol 10(5 Pt 1):803–17, 1984

    PubMed  CAS  Google Scholar 

  15. Barre PS, Shaffer JW, Cartner JR: Multiplicity of neurilemomas in upper extremity. J. Hand Surg (Am) 12(2):307–11, 1987

    CAS  Google Scholar 

  16. Basaglia P, Serra L, Foseolo AM, et al: Coexistence of Kaposi’s sarcoma and immunoblastic lymphoma. Minerva 78(3):187–91, 1987

    CAS  Google Scholar 

  17. Bellmunt Molins J, Bonfil Cosp X, Giralt Sagredo J, et al:Cancer of the lung as a second neoplasm in patients with carcinoma of the colorectum: apropos of 4 cases. Med Clin (Barc) 86(14):594–6, 1986

    CAS  Google Scholar 

  18. Benisch B, Peison B, Kannerstein M, et al: Malignant melanoma originating from intradermal nevi. A clinicopathologic entity. Arch Dermatol 116(6):696–8, 1980

    PubMed  CAS  Google Scholar 

  19. Bennett LL, Lesar MS, Tellis CJ: Multiple calcified chondrohamartomas of the lung: CT appearance. J Comput Assist Tomogr 9(1):l80–2, 1985

    Google Scholar 

  20. Bergonzi S, Guzzon A, Viganotti G, et al: Bone and visceral multicentric osteosarcoma. A case. Radiol Med (Torino) 73(6):579–81, 1987

    PubMed  CAS  Google Scholar 

  21. Bernstein JE, Medenica M, Soltani K, et al: Levodopa administration and multiple primary cutaneous melanomas. Arch Dermatol 116(9):1041–4, 1980

    PubMed  CAS  Google Scholar 

  22. Bezwoda WRT, Bernstein R, Pinto M, et al: B-cell chronic lymphatic leukemia in Hodgkin’s disease. Cancer 59(4):761–6, 1987

    PubMed  CAS  Google Scholar 

  23. Black MM, Hankey BF, Aron JL, Prorok PC: Possible immunological implications of an association between the stages of first and second independent breast cancers. Breast Cancer Res Treat 4(2):95–104, 1984

    PubMed  CAS  Google Scholar 

  24. Blitzer A; Som ML: Thyroid carcinoma in a patient with a coexisting functional adenoma. Otolaryngol Head Neck Surg 87(6):768–74, 1979

    PubMed  CAS  Google Scholar 

  25. Blum MD, Bahnson RR, Carter MF: Urologica manifestations of von Recklinghausen neurofibromatosis. Urology 26(3):209–17, 1985

    PubMed  CAS  Google Scholar 

  26. Bogdasarian RS, Lotz PR: Multiple simultaneous paragangliomas of the head and neck in association with multiple retroperitoneal pheochromocytomas. Otolaryngol Head Neck Surg 87(5):648–52, 1979

    PubMed  CAS  Google Scholar 

  27. Boissonnas A, Buttin S, Khalifa P, et al: Carcinoid tumor of the ampulla of Vater and Recklinghausen’s neurofibromatosis. Ann Med Interne (Paris) 136(1):46–8, 1985

    CAS  Google Scholar 

  28. Bordas X, Vives P, Marti R, et al: Multiple clear-cell acanthoma. Med Cutan Ibero Lat Am 12(6):457–60, 1984

    PubMed  CAS  Google Scholar 

  29. Borrelli M, Glina S, Wroclavski ET, et al: Vesical haemangioma. Report of two cases. Int Urol Nephrol 16(2):109–14, 1984

    PubMed  CAS  Google Scholar 

  30. Brocheriou C, Baudin JP, Verola O: Cylindroma on a pleomorphic adenoma. Apropos of 2 case reports. Rev Stomatol Chir Maxillofac 86(1):36–40, 1985

    PubMed  CAS  Google Scholar 

  31. Brownstein MH: The genodermatopathology of adnexal tumors. J Cutan Pathol 11(5):457–65, 1984.

    PubMed  CAS  Google Scholar 

  32. Burck U, Arnold H, Siebert J: Unilateral skin lesions associated with multiple neoplasms. Dermatologica 168(2):78–81, 1984

    PubMed  CAS  Google Scholar 

  33. Burger P, Villinberg E, Shmidt F: The problem of multiple tumors. Khirurgiia (Mos) (9):9–11, 1986

    Google Scholar 

  34. Byrd R: Late effects of treatment of cancer in children. Pediatr Clin North Am 32(3):835–57, 1985

    PubMed  CAS  Google Scholar 

  35. Calcaterra TC, Paglia D: The coexistence of parathyroid adenoma and thyroid carcinoma. Laryngoscope 89(7 Pt 1):1166–9, 1979

    PubMed  CAS  Google Scholar 

  36. Cappablanca P, De Chiara A, Spaziante R, et al: Metastasis of carcinoma to an intracranial meningioma. Acta Neurol (Napoli) 7(6):482–93, 1985

    Google Scholar 

  37. Carbone A, Volpe R: Kaposi’s sarcoma in lymph nodes concurrent with Hodgkin’s disease. Am J Clin Pathol 80(2):228–30, 1983

    PubMed  CAS  Google Scholar 

  38. Carrasco D, Prieto M, Pallardo L, et al: Multiple hepatic adenomas after long-term therapy with testosterone enanthate. Review of the literature. J Hepatol 1(6):573–8, 1985

    PubMed  CAS  Google Scholar 

  39. Carrato A, Filippa D, Koziner B: Hodgkin’s disease after treatment of non-Hodgkin’s lymphoma. Cancer 60(4):887–96, 1987

    PubMed  CAS  Google Scholar 

  40. Caya JG, Choi H, Tieu TM, et al: Hodgkin’s disease followed by mycosis fungoides in the same patient. Case report and literature review. Cancer 53(3):463–7, 1984

    PubMed  CAS  Google Scholar 

  41. Cayot F, Bastien H, Justrabo E, et al: Multiple paragangliomas of the neck localized in the thyroid cancer associated with parathyroid adenoma. Sem Hop Paris 58(35):2004–7, 1982

    PubMed  CAS  Google Scholar 

  42. Cellerier P, Chiras J, Gray F, et al: Computed tomography in primary lymphoma of the brain. Neuroradiology 26(6):485–92, 1984

    PubMed  CAS  Google Scholar 

  43. Chaoui A, Achour M, Bakkali KA, et al: Multiple cancers. Apropos of a quadruple cancer. J Gynecol Obstet Biol Reprod (Paris) 14(6):709–20, 1985

    CAS  Google Scholar 

  44. Chapnik JS: The controversy of Warthin’s tumor. Laryngoscope 93(6):695–716, 1983

    PubMed  CAS  Google Scholar 

  45. Chen KT, Hoffman KD, Hendricks EJ: Angiosarcoma following therapeutic irradiation. Cancer 44(6):2044–8, 1979

    PubMed  CAS  Google Scholar 

  46. Chevrant-Breton J, Dunn JE, Laudren A: Multiple glomus tumors associated with multiple neoplasias. Dermatologica 168(6):290–2, 1984

    PubMed  CAS  Google Scholar 

  47. Chiba S, Okada K, Numakunai S, et al: A case of equine thyroid follicular carcinoma accompanied with adenohypophysial adenoma. Nippon Juigaku Zasshi 49(3):551–4, 1987

    PubMed  CAS  Google Scholar 

  48. Chomett G, Auriol M, Guilbert F: Histoenzymological and ultrastructural study of a bifocal calcifying epithelial odontogenic tumor. Characteristics of epithelial cells and histogenesis of amyloid-like material. Virchows Arch (A) 403(1):67–76, 1984

    Google Scholar 

  49. Chomette G, Auriol M, Guilbert F: Bifocal odontogenic calcified epithelial tumor (Pindborg’s tumor). A morphologic and ultrastructural study. Rev Stomatol Chir Maxillofac 85(4):329–36, 1984a.

    CAS  Google Scholar 

  50. Chooi KF, Little PB: Immunoblastic lymphoma and cholangiocarcinoma in a cat. Vet Rec 120(24):578–9, 1987

    PubMed  CAS  Google Scholar 

  51. Coffman B, Crum E, Forman, WB: Two primary carcinomas of the lung: adenocarcinoma and a metachronous squamous cell carcinoma. A case report and review of the literature. Cancer 51(1):124–6, 1983

    PubMed  CAS  Google Scholar 

  52. Cohen-Salmon D, Michel RP, Wang NS, et al: Pulmonary carcinosarcoma and carcinoma: report of a case studied by electron microscopy, with critical review of the literature. Ann Pathol 5(2):115–24, 1985

    PubMed  CAS  Google Scholar 

  53. Coleman MP: Multiple primary malignancy in England and Wales, 1971–80: A pilot study of OPCS records. Community Med 9(1):15–24, 1987

    PubMed  CAS  Google Scholar 

  54. Coupe MO, Whittaker SJ, Thatcher H: Multicentric reticulohistiocytosis. Br J Dermatol 116(2):245–7, 1987

    PubMed  CAS  Google Scholar 

  55. Curnen MG, Thompson WD, Weston JF, Flannery JT: Cancer prevention: the tumor registry connection. Cancer Detect Prev 7(3):191–9, 1984

    PubMed  CAS  Google Scholar 

  56. Danoff A, Jormark S, Lorber D, et al: Adrenocortical micronodular dysplasia cardiac myxomas, lentigines, and spindle cell tumors. Arch Intern Med 147(3):443–8, 1987

    PubMed  CAS  Google Scholar 

  57. DeAngelis LM, Kelleher MB, Post KD, et al: Multiple paragangliomas in neurofibromatosis: a new neuroendocrine neoplasia. Neurology 37(1):129–33, 1987

    PubMed  CAS  Google Scholar 

  58. Deeg H J, Storb R, Thomas ED: Bone marrow transplantation: a review of delayed complications. Br J Haematol 57(2):185–208, 1984

    PubMed  CAS  Google Scholar 

  59. De Rosa G, Happi C, Patrizio P, et al: Breast carcinoma metastasized in ovarian thecoma (a case report). Eur J Gynaecol Oncol 6(2):138–42, 1985

    PubMed  Google Scholar 

  60. DeShryver K, Santa Cruz DJ: So-called glandular schwannoma: ependymal differentiation in a case. Ultrastruct Pathol 6(2–3):167–75, 1984

    Google Scholar 

  61. Detky G: Carcinoma of the appendix arising on the basis of a mucinous cystadenoma. Zenrtralbl Allg Pathol 130(2):139–42, 1985

    CAS  Google Scholar 

  62. Deutsch E, Eilon A, Zelig S, Ariel I: Synchronous bilateral oncocytoma of the parotid glands. A case report. ORL J Otorhinolaryngol Relat Spec 46(2):66–8, 1984

    PubMed  CAS  Google Scholar 

  63. Dhermy P, Sekkat A, Moussaoui M, et al: Ganglioneuroblastoma of the orbit. J Fr Ophtalmol 8(2):139–46, 1985

    PubMed  CAS  Google Scholar 

  64. Dieminger HJ, Friebel L, Bethmann R: Primary cancer of a Morgagni hydatid. Zentralbl Gynakol 107(7):442–5, 1985

    PubMed  CAS  Google Scholar 

  65. Doihara H, Takashima S, Usuki H, et al: Pleomorphic adenocarcinoma of the pancreas with extrapancreatic proliferation. Gan No Rinsho 33(1):107–14, 1987

    PubMed  CAS  Google Scholar 

  66. Dommes M, Thiede A, Hamelmann H: Locoregional recurrence following the operative treatment of rectal cancer. Basic principles of prevention and therapy. Zentralbl Chir 110(2–3):159–71, 1985

    PubMed  CAS  Google Scholar 

  67. Donoso LA, Rorke LB, Shields JA, et al: S-antigen immunoreactivity in trilateral retinoblastoma. Am J Ophthalmol 103(1):57–62, 1987.

    PubMed  CAS  Google Scholar 

  68. Doron Y, Gruszkiewicz J: Metastasis of invasive carcinoma of the breast to an extradural meningioma of the cranial vault. Cancer 60(5):1081–4, 1987

    PubMed  CAS  Google Scholar 

  69. Dorr FA, Coltman CA Jr: Second cancers following antineoplastic therapy. Curr Probl Cancer 9(2):1–43, 1985

    PubMed  CAS  Google Scholar 

  70. Doumith R, de Gennes JL, Cabane JP et al: Pituitary prolactinoma, adrenal aldosterone-producing adenomas, gastric schwannoma and colonic polyadenomas: a possible variant of multiple endocrine neoplasia (MEN) type I. Acta Endocrinol (Copenh) 100(2):189–95, 1982

    CAS  Google Scholar 

  71. Dralle H, Altenahr E: Pituitary adenoma, primary parathyroid hyperplasia and papillary (non-medullary) thyroid carcinoma. A case of multiple endocrine neoplasia (MEN). Virchows Arch (Pathol Anat) 381(2):179–87, 1979

    CAS  Google Scholar 

  72. Ducatman BS, Scheithauer BW, Piepgras DG, Reiman HM: Malignant peripheral nerve sheath tumors in childhood. J. Neurooncol 2(3):241–8, 1984.

    PubMed  CAS  Google Scholar 

  73. Ehlers N: Importance of age in management of retinoblastoma of the first eye. Acta Radiol (Oncol) 23(2–3):377–80, 1984

    Google Scholar 

  74. Einer AM, Gabibov GA, Lobkova EF: Unusual tremor in a patient with a local lesion of the brain. Zh Nevropatol Psikhiatr 84(4):530–3, 1984

    Google Scholar 

  75. Elvestad K, Henriques UV, Kroustrup JP: Insulin-producing islet cell tumor in an ectopic pancreas of a red fox (Vulpes vulpes). J Wildl Dis 20(1):70–2, 1984

    PubMed  CAS  Google Scholar 

  76. Engelke H, Christophers E: Leiomyomatosis cutis et uteri. Acta Derm Venereol (Suppl) (Stockh)59(85):51–4, 1979

    CAS  Google Scholar 

  77. Eridani S, Singh AK: Gastric non-Hodgkin’s lymphoma after successful treatment of Hodgkin’s disease. Oncology 43(2):107–9, 1986

    PubMed  CAS  Google Scholar 

  78. Eschenbach C, Schmitz-Moormann P, Gutjahr P: Primary carcinoma of the liver following lymphoblastic leukemia in childhood. Klin Paediatr 192(2):130–3, 1980

    CAS  Google Scholar 

  79. Ettinger LJ, Freeman AI: Hepatoma in a child with neurofibromatosis. Am J Dis Child 133(5):528–31, 1979

    PubMed  CAS  Google Scholar 

  80. Farwell J, Flannery JT: Second primaries in children with central nervous system tumors. J Neurooncol 2(4):371–5, 1984

    PubMed  CAS  Google Scholar 

  81. Ferlito A, Doglioni C, Bontempini L, Arrigoni A: Metachronous coexistence of laryngeal pseudolymphoma and squamous cell carcinoma. An unreported case. ORL J Otorhinolaryngol Relat Spec 46(4):202–9, 1984

    PubMed  CAS  Google Scholar 

  82. Forslund T, Hording L, Timonen T, Laasonen L: Two different primary lung malignancies after a successful kidney transplantation. Acta Radiol (Oncol) 23(6):411–4, 1984

    CAS  Google Scholar 

  83. Foulques H, Timbal Y, Jardin A: Bilateral testicular cancer of different histological types. J Urol (Paris) 90(5):369–74, 1984

    CAS  Google Scholar 

  84. Frazer AK, Victoratos GC: Multiple disparate cranial neoplasms. Cancer 44(6):2312–5, 1979

    PubMed  CAS  Google Scholar 

  85. Fryns JP, Haspeslagh M, de Muelenaere A, et al: 9p Trisomy/18p distal monosomy and multiple cutaneous leiomyomata. Another specific chromosomal site (18pter) in dominantly inherited multiple tumors? Hum Genet 70(3):284–6, 1985

    PubMed  CAS  Google Scholar 

  86. Furuta T, Kanematsu T, Sonoda T, et al: Independent occurrence of hepatocellular and cholangiocellular cancer nodules in the liver. Eur J Surg Oncol 13(1):69–73, 1987

    PubMed  CAS  Google Scholar 

  87. Galvin RJ, Kendall BE: Pituitary adenoma and orbital haemangioma: a case report. Br J Ophthalmol 63(3):200–3, 1979.

    PubMed  CAS  Google Scholar 

  88. Ganzen TN, Tsvetkova DA: Bronchiolar-alveolar cancer in idiopathic fibrosing alveolitis. Arkh Patol 46(6):56–61, 1984

    PubMed  CAS  Google Scholar 

  89. Gerlach H, Bahn H, Wessel H, et al: IgM/kappaimmunoblastoma of the brain following Hodgkin’s disease. Report on a clinical case and review of literature. Zentralbl Allg Pathol 129(4):343–56, 1984

    PubMed  CAS  Google Scholar 

  90. Giovannini M, Payan MJ, Choux R, et al: Association, in the same patient, of benign hepatic duct adenoma, thyroid adenocarcinoma and colonic adenocarcinoma. Presse Med 16(28):1372, 1987

    PubMed  CAS  Google Scholar 

  91. Golan A, Bloch B: Ovarian dysgerminoma with embryonal carcinoma: a case reporte. S Afr Med J 56(14):575–6, 1979

    PubMed  CAS  Google Scholar 

  92. Greene MH, Clark JW, Blayney DW: The epidemiology of ovarian cancer. Semin Oncol 11(3):209–26, 1984

    PubMed  CAS  Google Scholar 

  93. Guillaume JC, Guevel C, Zeller J, Touraine R: Cutaneous prickle-cell epitheliomas and visceral cancer. Ann Dermatol Venereol 112(1):21–4, 1985

    PubMed  CAS  Google Scholar 

  94. Hakulinen T, Isomaki HA, Kneki P: Multiple tumor incidence in patients with rheumatoid arthritis or allied disorders. J Chronic Dis 38(9):775–9, 1985

    PubMed  CAS  Google Scholar 

  95. Herbst EW, Utz W: Multifocal dermal-type basal cell adenomas of parotid glands with co-existing dermal cylindromas. Virchows Arch (A) 403(1):95–102, 1984

    CAS  Google Scholar 

  96. Herson D, Fonncin JF, Rouques C, Fauchon F: Primary lymphoma of the peripheral and central nervous system. Rev Neurol (Paris) 140(4):284–7, 1984

    PubMed  CAS  Google Scholar 

  97. Heston JF, et al: Forty-five years of cancer incidence in Connecticut 1935–79. National Cancer Institute Monograph 70, NIH Publ No. 86–2652, 1986.

    Google Scholar 

  98. Higgins RJ, Poole A, Wilson KE: Multicentric lymphosarcoma in a Saanen goat. Vet Rec 114(7):170, 1984

    PubMed  CAS  Google Scholar 

  99. Himmele JC, Rabenhorst B, Werner D: Inhibition of Lewis lung tumor growth and metastasis by Ehrlich ascites tumor growing in the same host. J Cancer Res Clin Oncol 111(2):160–5, 1986

    PubMed  CAS  Google Scholar 

  100. Hoffman RW, Gardner DW, Mitchell FL: Intrathoracic and multiple abdominal pheochromocytomas in von Hippel-Lindau disease. Arch Intern Med 142(10):1962–4, 1982

    PubMed  CAS  Google Scholar 

  101. Hulat A, Michel P, Cornut F, Hustin J: Development of aggressive cystosarcoma phyllodes after conservative treatment of breast adenocarcinoma. Bull Cancer (Paris) 72(2):80–6, 1985

    Google Scholar 

  102. Hull MT, Gonzalez-Crussi F, Grosfeld JL: Multiple pulmonary fibroleiomyomatous hamartomata in childhood. J Prediatr Surg 14(4):428–31, 1979

    CAS  Google Scholar 

  103. Hull MT, Warfel KA, Muller J, et al: Familial islet cell tumors in von Hippel-Lindau’s disease. Cancer 44(4):1523–6, 1979

    PubMed  CAS  Google Scholar 

  104. Hutcheon DF, Bayless TM, Cameron JL, et al: Hormonemediated watery diarrhea in a family with multiple endocrine neoplasms. Ann Intern Med 90(6):932–4, 1979

    PubMed  CAS  Google Scholar 

  105. Imai Y, Fukase M, Tsutsumi M, et al: A case of multiple endocrine neoplasia type IIb: endocrinological evaluation and family screening. Endocrinol Jpn 29(1):49–56, 1982

    PubMed  CAS  Google Scholar 

  106. Iranzo P, Martin E, del Olmo JA, Mascaro JM: Birt-Hogg-Dube syndrome as an expression of tuberous sclerosis. Apropos of 2 personal cases in 2 sisters. Med Cutan Ibero Lat Am 131(2):145–9, 1985

    Google Scholar 

  107. Jackson R: Epidermotropic malignant melanoma: the distinction between metastatic and new primary lesions in the skin. Can J Surg 27(6):533–5, 1984

    PubMed  CAS  Google Scholar 

  108. Jacquillat C, Khayat D, Desprez-Curely JP, et al:Non-Hodgkin’s lymphoma occurring after Hodgkin’s disease. Four new cases and a review of the literature. Cancer 53(3):459–62, 1984

    PubMed  CAS  Google Scholar 

  109. Junien-Lavillauroy C, Bolla M, Reyt E, Guenoun A: Retrospective study of the treatment of piriform sinus cancers. Apropos of 97 cases. Ann Otolaryngol Chir Cervicofac 102(5):293–8, 1985

    PubMed  CAS  Google Scholar 

  110. Kasantikul V, Brown WJ, Netsky MG: Mesenchymal differentiation in trigeminal neurilemma. Cancer 50(8):1568–71, 1982

    PubMed  CAS  Google Scholar 

  111. Kasumi F: Bilateral breast carcinoma. Nippon Geka Gakkai Zasshi 86(3):266–79, 1985

    PubMed  CAS  Google Scholar 

  112. Katenkamp D, Watzig V: Multiple neuroendocrine carcinomas (so-called Merkel cell tumours) of the skin. Report on two cases with unique clinical course. Virchows Arch (A) 404(4):403–11, 1984

    CAS  Google Scholar 

  113. Kaufman D, Gordon LI, Variakojis D, et al: Successfully treated Hodgkin’s disease followed by mycosis fungoides: case report and review of the literature. Cutis 39(4):291–6, 1987

    PubMed  CAS  Google Scholar 

  114. Kawano N, Morii S, Yada K, et al: Contiguous malignant astrocytoma and Wilms’-like tumor in the brain. Cancer 49(12):2505–12, 1982

    PubMed  CAS  Google Scholar 

  115. Kazantseva I A, Smirnova EA: Multiple primary carcinoid tumor of the stomach of complex structure. Arkh Patol 46(6);61–4, 1984

    Google Scholar 

  116. Kheir SM, Halpern NB: Paraganglioma of the duodenum in association with congenital neurofibromatosis. Possible relationship. Cancer 53(11):2491–6, 1984

    PubMed  CAS  Google Scholar 

  117. Knysh VI, Ananev, VS: Postoperative complications in colonic cancer patients. Vopr Onkol 31(5):52–8, 1985

    Google Scholar 

  118. Kofoed ML, Klemp P, Thestrup-Pederssen K: The Klippel-Trenaunay syndrome with acro-angiodermatitis (pseudo-Kaposi’s sarcoma). Acta Derm Venereol (Stockh) 65(1):75–7, 1985

    PubMed  CAS  Google Scholar 

  119. Kokshunova LE: Congenital multiple rhabdomyoma of the heart. Arkh Patol 42(1):63–5, 1980

    PubMed  CAS  Google Scholar 

  120. Kovalenko VL, Kulaev IA: Morphogenetic aspects of thyroid cancer with multiple growth foci. Vopr Onkol 27(5):17–22, 1981

    PubMed  CAS  Google Scholar 

  121. Kovarik J, Silberbauer K, Woloszczuk W, et al: Sipple syndrome (bilateral phaeochromocytoma medullary C-cell carcinoma of the thyroid gland) with expectionally prolonged clinical course. Wien Klin Wochenschr 94(13):340–5, 1982

    PubMed  CAS  Google Scholar 

  122. Krolls SO, Schaffer RC, O’Rear JW: Chondrosarcoma and osteosarcoma of the jaws in the same patient. Oral Surg 50(2):146–50, 1980

    PubMed  CAS  Google Scholar 

  123. Kuyer PP, Rosenbusch G, Yap SH, et al: The variable picture of gastric carcinoid. ROFO 146(2):184–8, 1987

    PubMed  CAS  Google Scholar 

  124. Kwekkeboom DJ, Thomas LL, Gerrits WB, Goudsmit R: Chronic lymphocytic leukaemia and associated second malignancy. Neth J Med 29(1):2–4, 1986

    PubMed  CAS  Google Scholar 

  125. Labauge R, Pages A, Pages M, et al: Haemorrhagic necrosis of a pituitary adenoma in a case of multiple endocrine neoplasia. Rev Neurol (Paris) 136(2):149–56

    Google Scholar 

  126. Lacquet LK, Jongerius CM, Limburg M, Rensing JB: The triad mediastinal chemodectoma, chondroma of the lung and esophageal leiomyoma. Rev Pneumol Clin 40(1):63–7, 1984

    PubMed  CAS  Google Scholar 

  127. Lairmore MD, Knight AP, DeMartini JC: Three primary neoplasms in a goat: hepatocellular carcinoma, phaeochromocytoma and leiomyoma. J Comp Pathol 97(3):267–71, 1987

    PubMed  CAS  Google Scholar 

  128. Lederman SM, Martin EC, Laffey KT, et al: Hepatic neurofibromatosis, malignant schwannoma, and angiosarcoma in von Recklinghausen’s disease. Gastroenterology 92(1):234–9, 1987

    PubMed  CAS  Google Scholar 

  129. Levin S, Robinson RO, Aicardi J, Hoare RD: Computed tomography appearances in the linear sebaceous naevus syndrome. Neuroradiology 26(6):469–72, 1984

    PubMed  CAS  Google Scholar 

  130. Levine JH, Sagel J, Rosebrock G, et al: Prolactin-secreting adenoma as part of the multiple endocrine neoplasis-type I (MEN-I) syndrome. Cancer 43(6):2492–6, 1979

    PubMed  CAS  Google Scholar 

  131. Liebe S, Wohlgemuth B: Localization of colon adenomas in relation to age and sex. A colonoscopy study. Dtsch Z Verdau Stoffwechselkr 44(1):16–21, 1984

    PubMed  CAS  Google Scholar 

  132. Link MP, Donaldson SS, Kempson RL, et al: Acute nonlymphocytic leukemia developing during the course of Ewing’s sarcoma. Med Pediatr Oncol 12(3):194–200, 1984

    PubMed  CAS  Google Scholar 

  133. Liskow AS, Neugut AI, Benson M, et al: Multiple primary neoplasms in association with prostate cancer in black and white patients. Cancer 59(2):380–4, 1987

    PubMed  CAS  Google Scholar 

  134. Lium B, Moe L: Hereditary multifocal renal cystadenocarcinomas and nodular dermatofibrosis in the German shepherd dog: macroscopic and histopathologic changes. Vet Pathol 22(5):447–55, 1985

    PubMed  CAS  Google Scholar 

  135. Livshits MA, Dymarskii LIu: Differential diagnosis of primary and metastatic ovarian tumors in patients treated for breast cancer. Vopr Onkol 31(3):63–8, 1985

    PubMed  CAS  Google Scholar 

  136. Logio T, Rubin RJ, Aucoin E, Salazar G: Intra-abdominal desmoid tumor. Dis Colon Rectum 23(6):423–5, 1980

    PubMed  CAS  Google Scholar 

  137. Lookingbill DP, Kreider JW, Howell MK, et al: Human papillomavirus type 16 in bowenoid papulosis, intraoral papillomas, and squamous cell carcinoma of the tongue. Arch Dermatol 123(3):363–8, 1987

    PubMed  CAS  Google Scholar 

  138. Lotze W, Bergander S: Leydig cell tumor with pronounced virilization. Zentralbl Gynakol 107(10):647–50, 1985

    PubMed  CAS  Google Scholar 

  139. Lynch HT, Fusaro RM, Danes BS, et al: A review of hereditary malignant melanoma including biomarkers in familial atypical multiple mol:e melanoma syndrome. Cancer Genet Cytogenet 8(4):325–58, 1983

    PubMed  CAS  Google Scholar 

  140. Malone MJ, Johnson PR, Jumper BM, et al: Renal angiomyolipoma: 6 case reports and literature review. J Urol 135(2):349–53, 1986

    PubMed  CAS  Google Scholar 

  141. Markovic B: Balkan nephropathy and transitional cell carcinoma. Pathogenetic problems and the early phase of cancerogenesis. J Urol (Paris) 91(4):215–20, 1985

    CAS  Google Scholar 

  142. Marouteau D: Ovarian cancer 5 years after hysterectomy with adnexectomy for a benign lesion. Apropos of a case. J Gynecol Obstet Biol Reprod (Paris) 14(2):201–3, 1985

    CAS  Google Scholar 

  143. Marshall FF, Little B: Malignant gonadal stromal tumor of the testis arising with a malignant teratoma. J Urol 136(5):1069–91, 1986

    Google Scholar 

  144. Martin C, Martin H, Portafaix M, Saby JL: Peculiarly slow development of several acoustic neuromas. Management. Ann Otolaryngol Chir Cervicofac 102(1):19–29, 1985

    PubMed  CAS  Google Scholar 

  145. Maruchi N, Brian D, Ludwig J, et al: Cancer of the pancreas in Olmsted County, Minnesota, 1935–74, Mayo Clin Proc 54(4):245–9, 1979

    PubMed  CAS  Google Scholar 

  146. Mashiyama S, Mori T, Seki H, et al: Multiple brain tumours with von Recklinghausen’s disease. Acta Neurochir (Wien) 84(1–2):29–35, 1987

    CAS  Google Scholar 

  147. Matveev BP, Gotsadze DT, Bukharkin BV, Cheban BL: Bilateral tumors of the testis. Vopr Onkol 30(2):65–9, 1984

    PubMed  CAS  Google Scholar 

  148. McDivitt RW: Breast cancer multicentricity. Monogr Pathol (25):139–48, 1984

    Google Scholar 

  149. Megighian D, Zorat PL: A rarely observed case of primary multiple carcinomas of the head and neck. Arch Otorhinolaryngol 242(1):7–12, 1985

    PubMed  CAS  Google Scholar 

  150. Mezinova NN, Patrusheva AS: Risk factors for the development of endometrial cancer in uterine myoma. Vopr Onkol 31(6):60–4, 1985

    PubMed  CAS  Google Scholar 

  151. Mikhailov AA, Demin VN, Martyniuk VV, Denisenko IuV: Possibilities of the local removal of villous tumors of the large intestine. Vopr Onkol 30(8):72–6, 1984

    PubMed  CAS  Google Scholar 

  152. Moinar L, Svastics E, Rahoty P: Gastric carcinoma associated with other malignant tumours. Acta Chir Hung 26(1):19–26, 1985

    Google Scholar 

  153. Montgomery P, Kuhn JP, Berger PE, Fisher J: Multifocal nephroblastomatosis: clinical significance and imaging. Pediatr Radiol 14(6):392–5, 1984

    PubMed  CAS  Google Scholar 

  154. Moseley HS, Giuliano AE, Storm FK 3d, et al: Multiple primary melanoma. Cancer 43(3):939–44, 1979

    PubMed  CAS  Google Scholar 

  155. Motomochi M, Makita Y, Nabeshima S, et al: A case of Maffucci’s syndrome with intracranial chondroma. No Shinkai Geka 7(10):1011–5, 1979

    CAS  Google Scholar 

  156. Mouriquand J, Malka JG, Ollagnier C, et al: Post-therapeutic development of small cell epitheliomas to malphighian epitheliomas, or initially composite forms? Apropos of 3 cases, review of the literature. Rev Pneumol Clin 40(1):21–5, 1984

    PubMed  CAS  Google Scholar 

  157. Muller H, Burki N, Gencik A, et al: Familial cancer. Initial results of an inquiry into its occurrence in Basel. Soz Praventivmed 30(1):28–32, 1985

    PubMed  CAS  Google Scholar 

  158. Murayama H, Kikuchi M, Imai T: Myelolipoma in adenoma of accessory adrenal gland. Pathol Res Pract 164(2):207–13, 1979.

    PubMed  CAS  Google Scholar 

  159. Nakagawa K, Sakaki S, Fujita H, et al: A case of primary intracranial malignant lymphoma associated with gastric carcinoma. Gan No Rinsho 33(8):937–42, 1987

    PubMed  CAS  Google Scholar 

  160. Nepomniashchaia KV: Multiple primary malignant paragangliomas of the bladder and retroperitoneal space. Arkh Patol 41(4):54–7, 1985

    Google Scholar 

  161. Nirjima T, Kuroki Y, Uchida T, et al: Nursing of a patient with bilateral breast cancer developing at different times and followed by repeated recurrences and metastases. Kurinikaru Sutadi 7(8):669–76, 1986

    Google Scholar 

  162. Oakley RH, Carty H, Cudmore RE: Multiple benign mesenchymomata of the chest wall. Pediatr Radiol 15(1):58–60, 1985

    PubMed  CAS  Google Scholar 

  163. Oberg K, Walinder O, Bostrom H, et al: Peptide hormone markers in screening for endocrine tumors in multiple endocrine adenomatosis Type I. Am J Med 73(5):619–30, 1982

    PubMed  CAS  Google Scholar 

  164. Ohuchi N, Abe R, Takahahsi T, Tazuka F: Origin and extension of intraductal papillomas of the breast: a threedimensional reconstruction study. Breast Cancer Res Treat 4(2):11–28, 1984

    Google Scholar 

  165. Okinaka Y, Sekitani T: Mucoepidermoid carcinoma of the vocal cord. Report of a case. ORL J Otorhinolaryngol Relat Spec 46(3):139–46, 1984

    PubMed  CAS  Google Scholar 

  166. O’Neil MB Jr, Grehl TM, Hurley EJ: Cardial myxomas: a clinical diagnostic challenge. Am J Surg 138(1):68–76, 1979.

    PubMed  Google Scholar 

  167. Ott RA, Eugene J, Kollin J, et al: Primary pulmonary angiosarcoma associated with multiple synchronous neoplasms. J Surg Oncol 35(4):269–76, 1987

    PubMed  CAS  Google Scholar 

  168. Overly WL, Jakubek DJ: Multiple squamous cell carcinomas and human immunodeficiency virus infection. Ann Intern Med 106(2):334, 1987

    PubMed  CAS  Google Scholar 

  169. Papac RJ: Medical aspects of head and neck cancer. Cancer Invest 3(5):435–44, 1985

    PubMed  CAS  Google Scholar 

  170. Paul SM, Bacharach B: Three synchronous bilateral lung tumors: a case report. J Surg Oncol 34(4):253–7, 1987

    PubMed  CAS  Google Scholar 

  171. Peer J, Zimmerman LE: Ocular metastases from transitional cell carcinoma of the urinary tract. Graefes Arch Clin Exp Ophthalmol 221(4):137–41, 1984

    CAS  Google Scholar 

  172. Perri RT, Allen JI, Okan MM, et al: Simultaneous presentation of relapsing Hodgkin’s lymphoma. Med Pediatr Oncol 13(3):122–5, 1985

    PubMed  CAS  Google Scholar 

  173. Pianov RP: Diffuse nephroblastomatosis and carcinoid tumor of the pancrease in a newborn infant. Arkh Patol 46(6):64–7, 1984

    CAS  Google Scholar 

  174. Pingitore R, Campani D: Salivary gland involvement in a case of dermal eccrine cylindroma of the scalp (turban tumor). Report of a case with lung metastases. Tumori 70(4):385–8, 1984

    PubMed  CAS  Google Scholar 

  175. Polinari U, Dugo D, Di Folco S, et al: Malignant fibrous histiocytoma. Report of a case and review of the literature. Eur J Gynaecol Oncol 6(2):205–8, 1985

    Google Scholar 

  176. Polterauer P, Ulrich W: Primary liver carcinoma. Results of 268 autopsies. Onkologie 5(2):76–8, 1982

    PubMed  CAS  Google Scholar 

  177. Poluektov IuA, Zalkind PR, Ugolnikowa TIu: Primarymultiple malignant tumors and their metastasis. Klin Khir (5):45–6, 1987.

    Google Scholar 

  178. Ponhold W, Schilling R, Vergesslich K, et al: Sonographic demonstration of an unusual bladder wall enlargement in a child with non-Hodgkin lymphoma. Padiatr Padol 20(4):397–402, 1985

    PubMed  CAS  Google Scholar 

  179. Portlock CS: Hodgkin’s disease. Med Clin North Am 68(3):729–40, 1984

    PubMed  CAS  Google Scholar 

  180. Prat J, Scully RE: Sarcomas in ovarian mucinous tumors: a report of two cases. Cancer 44(4):1327–31, 1979.

    PubMed  CAS  Google Scholar 

  181. Prat J, Scully RE: Ovarian mucinous tumors with sarcomalike mural nodules: a report of seven cases. Cancer 44(4):1332–44, 1979

    PubMed  CAS  Google Scholar 

  182. Prause JU, Jensen OA, Eisgart F, et al: Bilateral diffuse malignant melanoma of the uvea associated with large cell carcinoma, giant cell type, of the lung. Case report of a newly described syndrome. Ophthalmologica 189(4):221–8, 1984

    PubMed  CAS  Google Scholar 

  183. Preissig SH, Smith MT, Huntington HW: Rhabdomyosarcoma arising in a pineal teratoma. Cancer 44(1):281–4, 1979

    PubMed  CAS  Google Scholar 

  184. Pruglo IuV, Sivtsova NL, Gaidar IuA, et al: Combined gastrinoma of the duodenum and glucagonoma of the pancreas. Arkh Patol 49(2):65–70, 1987

    PubMed  Google Scholar 

  185. Punto L, Fogelholm R, Puranen M, et al: Multiple intracranial meningiomas associated with intracranial arterial aneurysm. Ann Clin Res 16 Suppl 40:20–2, 1984

    Google Scholar 

  186. Ravisse P, Boche R: Histopathology of Kaposi’s sarcoma. Bull Soc Pathol Exot Filiales 77(4 Pt 2):533–45, 1984

    PubMed  CAS  Google Scholar 

  187. Ray P, Sharifi R, Ortolano V, Guinan P: Involvement of the genitourinary system in multiple primary malignant neoplasms: a review. J Clin Oncol 1(9):574–81, 1983

    PubMed  CAS  Google Scholar 

  188. Richter P, Lotze W: Therapy and course of a malignant double melanoma. Zentralbl Gynakol 107(12):769–71, 1985

    PubMed  CAS  Google Scholar 

  189. Rockelein G: Metastasizing mucoepidermoid carcinoma of the parotid gland. Laryngol Rhinol Otol (Stuttg) 64(7):338–41, 1985

    CAS  Google Scholar 

  190. Rocken H: A mixed mamma tumor, a theca cell tumor and a leiomyoma in a bitch. Berl Munch Tierärztl Wochenschr 98(6):220–l, 1985

    PubMed  CAS  Google Scholar 

  191. Rohr J, Gauthier G: Bilateral meningiomas of the optic nerves associated with partial unilateral Duane’s syndrome. Rev Neurol (Paris) 140(11):637–41, 1984

    PubMed  CAS  Google Scholar 

  192. Rosen PP: Lobular carcinoma in situ and intraductal carcinoma of the breast. Monogr Pathol (25):59–105, 1984

    PubMed  Google Scholar 

  193. Rosner F, Grunwald HW: Simultaneous occurrence of multiple myeloma and acute myeloblastic leukemia: fact or myth? Am J Med 76(5):891–9, 1984

    PubMed  CAS  Google Scholar 

  194. Roth A: An unusual renal tumor, associating nephroblastoma, nephroblastomatosis, teratoma, and cystic dysplasia with arterial hypertension and secretion of alpha-fetoprotein. J Urol (Paris) 90(1):7–10, 1984

    CAS  Google Scholar 

  195. Rothwell TL, Zu FN, Wills EJ, et al: Unusual multisystemic vascular lesions in a cat. Vet Pathol 22(5):510–2, 1985

    PubMed  CAS  Google Scholar 

  196. Rubesin S, Herlinger H, Sigal H: Granular cell tumors of the esophagus. Gastrointest Radiol 10(1):11–5, 1985

    PubMed  CAS  Google Scholar 

  197. Rueda-Leverone NG, Di Paola GR, Meiss RP, et al: Association of human papillomavirus infection and vulvar intraepithelial neoplasia: a morphological and immunohistochemical study of 30 cases. Gynecol Oncol 26(3):331–9, 1987

    PubMed  CAS  Google Scholar 

  198. Samsonov VA: Multiple primary tumors complicating prostatic cancer. Vopr Onkonl 31(1):101–5, 1985

    CAS  Google Scholar 

  199. Samsonov VA, Kolomoitsev SV: Dimorphic (transitional-anaplastic) ductal cancer of the prostate. Arkh Patol 46(2):71–3, 1984

    PubMed  CAS  Google Scholar 

  200. Sanchez-Pedreno P, Menacho R, Sotillo I, Camacho F: Coexistence of lineal verrucous and pigmentocellular nevi. Med Cutan Ibero Lat Am 12(4):323–5, 1984

    PubMed  CAS  Google Scholar 

  201. Sandbank M, Nodak E, Rotem A, et al: The heterogeneity of tumours associated with epidermodysplasia verruciformis. Acta Derm Venereol (Stockh) 67(1):79–82, 1987

    PubMed  CAS  Google Scholar 

  202. Sandstrom A, Larsson LG, Damber L: Occurrence of other malignancies in patients treated for basal cell carcinoma of the skin. A cohort study. Acta Radiol (Oncol) 23(4):227–30, 1984

    CAS  Google Scholar 

  203. Sanerkin NG, Woods CG: Fibrosarcomata and malignant fibrous histiocytomata arising in relation to enchondromata. J Bone Joint Surg (Br) 61-B(3):366–72, 1979

    CAS  Google Scholar 

  204. Schaefer G, Rosen PP, Lesser ML, et al:Breast carcinoma in elderly women: pathology, prognosis, and survival. Pathol Annu 19 Pt 1:195–219, 1984

    PubMed  Google Scholar 

  205. Schiffer J, Mundel G, Lahat E, et al: Multiple meningiomas in separate neuroaxial compartments in a child. Childs Brain 6(6):281–8, 1980

    PubMed  CAS  Google Scholar 

  206. Schifter S, Vendelbo L, Jensen OM, Kaae S: Ewing’s tumor following bilateral retinoblastoma. A case report. Cancer 51(9):1746–9, 1983

    PubMed  CAS  Google Scholar 

  207. Schlienger P, Calle R, Haye C, Vilcoq JR: Bone sarcoma and malignant tumors of the retina. Bull Cancer (Paris) 72(1):16–24, 1985

    PubMed  CAS  Google Scholar 

  208. Schmitt K, Tulzer W: Second tumor following Hodgkin’s disease. Pediatr Padol 19(3):259–62, 1984

    CAS  Google Scholar 

  209. Schwartz PL, Beards JA, Maris PJ: Tuberous sclerosis associated with a retinal angioma. Am J Ophthalmol 90(4):485–8, 1980

    PubMed  CAS  Google Scholar 

  210. Scott RS, Castro DJ: Treatment of condyloma acuminate with carbon dioxide laser: a prospective study. Lasers Surg Med 4(2):157–62, 1984

    PubMed  CAS  Google Scholar 

  211. Secker-Walker LM, Stewart EL, Todd A: Acute lymphoblastic leukaemia with t(4; 11) follows neuroblastoma: a late effect of treatment? Med Pediatr Oncol 13(1):48–50, 1985

    PubMed  CAS  Google Scholar 

  212. Seitz G, Schuder G: Neoplasm to neoplasm metastasis. Pheochromocytoma harboring a metastasis of breast cancer. Pathol Res Pract 182(2):228–32, 1987

    PubMed  CAS  Google Scholar 

  213. Sekiya S, Iwasawa H, Morikawa S, Takamizawa H: Malignant change of dermoid cysts of the ovary. Report on an adenosquamous cell carcinoma and a clear cell carcinoma. Eur J Gynaecol Oncol 5(1):16–20, 1984

    PubMed  CAS  Google Scholar 

  214. Sella A, Ro JY: Renal cell cancer: best recipient of tumor-totumor metastasis. Urology 30(1):35–8, 1987

    PubMed  CAS  Google Scholar 

  215. Severi, L (ed): Multiple Primary Malignant Tumours. Proc Vth Perugia Quadrennial Internat’l Conference on Cancer. Perugia: Division of Cancer Research, 1974

    Google Scholar 

  216. Shabtai F, Lask D, Kimchi D, et al: Concomitance of urogenital with lymphoid and intestinal malignancies: more than a coincidence. Urol Int 40(3):145–7, 1985

    PubMed  CAS  Google Scholar 

  217. Sheahan DS, Berman MA: Barrett’s mucosa with multiple carcinomas of the esophagus and oral cavity. J Clin Gastroenterol 8(1):103–1, 1986

    PubMed  CAS  Google Scholar 

  218. Shibuya H, Horiuchi J, Suzuki S, et al: Oral carcinoma of the upper jaw. Results of radiation treatment. Acta Radiol (Oncol) 23(5):331–5, 1984

    CAS  Google Scholar 

  219. Shimizu J, Hamashima Y, Tsuda H, et al: T-cell acute lymphoblastic leukemia relapsing as acute myelomonocytic leukemia and terminating possibly as chronic myelocytic leukemia. Am J Hematol 24(2):199–205, 1987

    PubMed  CAS  Google Scholar 

  220. Shimotsuma M, Tsukuda N, Hashimoto M, et al: A case of breast carcinoma possibly the result of malignant transformation of an intraductal papilloma in a 26-year period. Gan No Rinsho 33(2):193–8, 1987

    PubMed  CAS  Google Scholar 

  221. Shkhvatsabaya IK, Bronstein ME, Chikhladze NM, et al: Morphological changes in the adrenal cortex in different vairants of low-renin hyperaldosteronism. Comparison with the functional state of certain hormonal systems. Cor Vasa 27(2–3):103–10, 1985

    PubMed  CAS  Google Scholar 

  222. Shuangshoti S, Suwanwela C, Suwanwela N: Congenital osteolipoma of the skull. Arch Otolaryngol 108(7):454–7, 1982

    PubMed  CAS  Google Scholar 

  223. Sikurowa L, Morawski A, Piatkowski Z: Endodermal sinus tumor of the ovary. Clinicopathologic study of 6 cases. Oncology 36(4):187–92, 1979

    Google Scholar 

  224. Sjovall S, Kornhall S: Double tumours of the appendix: a rare entity. A case report. Acta Chir Scand 51(3):297–8, 1985

    Google Scholar 

  225. Smirnov O A, Lomakina II, Serezhin BS, Skripnik SV: Argyrophilic cells in endometrial adenocarcinoma with foci of squamous cell metaplasia (adenoacanthoma). Arkh Patol 47(3):53–5, 1985

    PubMed  CAS  Google Scholar 

  226. Sprengers DP, Knockaert DC, Van Steenbergen W, et al:Primary bile duct cancer and von Recklinghausen disease. Ann Intern Med 106(5):772, 1987

    PubMed  CAS  Google Scholar 

  227. Squire J, Gallie BL, Phillips RA: A detailed analysis of chromosomal changes in heritable and non-heritable retinoblastoma. Hum Genet 70(4):291–301, 1985

    PubMed  CAS  Google Scholar 

  228. Stamm B, Hedinger CE, Saremaslani P: Duodenal and ampullary carcinoid tumors. A report of 12 cases with pathological characteristics, polypeptide content and relation to the MEN I syndrome and von Recklinghausen’s disease (neurofibromatosis). Virchows Arch (A) 408(5):475–89, 1986

    CAS  Google Scholar 

  229. Steffens J, Friedmann W, Nagel R: Immunohistochemical and radioimmunological determination of beta-HCG and pregnancy-specific beta 1-protein in seminomas. Urol Int 40(2):72–5, 1985

    PubMed  CAS  Google Scholar 

  230. Stine KC, Goertz KK, Poisner AM, Lowman JT: Congestive heart failure, hypertension, and hyperreninemia in bilateral Wilms’ tumor: successful medical management. Med Pediatr Oncol 14(1):63–6, 1986

    PubMed  CAS  Google Scholar 

  231. Sugihara S, Nakahara T, Maruiwa M, et al: An autopsy case with a combination of hepatocellular carcinoma and cholangiocellular carcinoma. Gan No Rinsho 33(2):205–10, 19897

    Google Scholar 

  232. Svejda J. Lorenz I: Secondary tumors in cancer patients after therapy. Neoplasma 32(4):495–8, 1985

    PubMed  CAS  Google Scholar 

  233. Tarkkanen A, Karjalainen K: Excess of cancer deaths in close relative of patients with bilateral retinoblastoma. Ophthalmologic 189(3):143–6, 1984

    CAS  Google Scholar 

  234. Taylor DA, Bird AR, Jacobs P, et al: Simultaneous occurrence of multiple myeloma and chronic lymphocytic leukaemia. S Afr Med J 71(8):540, 19887

    Google Scholar 

  235. Teppo L, Pukkala E, Saxen E: Multiple cancer — an epidermiologic exercise in Finland. JNCI 75(2):207–17, 1985

    PubMed  CAS  Google Scholar 

  236. Terracini B, Pastore, G, Zurlo MG, et al: Late deaths and second primary malignancies among long-term survivors of childhood cancer: an Italian multicentre study. Eur J Cancer Clin Oncol 23(5):499–504, 1987

    PubMed  CAS  Google Scholar 

  237. Thomalla JV: Three primary tumors and no metastasis. Hosp Pract (Off) 21(4):138H, 1986

    Google Scholar 

  238. Tortella BJ, Matthews JB, Antonioli DA, et al: Gastric autonomic nerve (GAM) tumor and extra-adrenal paraganglioma in Carney’s triad. A common origin. Ann Surg 205(3):221–5, 1987

    PubMed  CAS  Google Scholar 

  239. Trakhtenberg AKh, Pirogov AI, Golbert ZV: Primary multiple cancer of both lungs. Vopr Onkol 30(1):23–3, 1984

    PubMed  Google Scholar 

  240. Trakhtenberg AKh, Pirogov AI, Frank GA: Multiple primary cancer in 1 lung. Vopr Onkol 31(2):17–25, 1985

    PubMed  Google Scholar 

  241. Trese MT, Foos RY, Hepler RS, et al:Orbital embryonal rhabdomyosarcoma and intracranial schwannoma. Arch Ophthalmol 97(10):1929–30, 1979

    PubMed  CAS  Google Scholar 

  242. Trinkmann R: Course of malignant histiocytosis. Ophthalmologic 189(4):177–9, 1984

    CAS  Google Scholar 

  243. Tsibel BN, Solodun IuV: Case of combined malignant adenoma of the hypophysis and astrocytoma. Arkh Patol 47(4):60–2, 1985

    PubMed  CAS  Google Scholar 

  244. Ueda J, Kobayashi Y, Itoh M, et al: Angiomyolipoma and renal cell carcinoma occurring in same kidney: CT evaluation. J Comput Assist Tomogr 11(2):340–1, 1987

    PubMed  CAS  Google Scholar 

  245. Valderrama E, Kahn LB, Wind E: Extraskeletal osteosarcoma arising in an ectopic hamartomatous thymus. Report of a case and review of the literature. Cancer 51(6):1132–7, 1983

    PubMed  CAS  Google Scholar 

  246. Valderrama E, Kalra J, Badlani G, et al: Simultaneous renal cell carcinoma squamous cell carcinoma of kidney. Urology 29(4):441–5, 1987

    PubMed  CAS  Google Scholar 

  247. Vio A, Barbanti F, Dell’Amore, D et al: Intraductal papillomas: diagnostic and surgical procedures. Ital J Surg Sci 15(1):51–5, 1985

    PubMed  CAS  Google Scholar 

  248. Volmer J: Intraductal (intracystic) papilloma of the male breast. Zentralbl Allg Pathol 129(6):513–9, 1984

    PubMed  CAS  Google Scholar 

  249. Vorherr H: Pathobiology of breast cancer — treatment implications. Eur J Obstet Gynecol Reprod Biol 17(2–3):219–35, 1984

    PubMed  CAS  Google Scholar 

  250. Wallach D, Kuffer R, Cottenot F: Epidermal nevus syndrome. A case with oral involvement. Rev Stomatol Chir Maxillofac 85(4):311–3, 1984

    PubMed  CAS  Google Scholar 

  251. Walther M, O’Brien DP 3d, Birch HW: Condylomata acuminate and verrucous carcinoma of the bladder: Case report and literature review. J Urol 135(2):362–5, 1986

    PubMed  CAS  Google Scholar 

  252. Warner TF, Gilbert EF, Ramirez G: Epidermatropism in melanoma. J Cutan Pathol 7(1):50–4, 1980

    PubMed  CAS  Google Scholar 

  253. Warner TF, Seo IS, Bennett JE: Minimal deviation melanoma with epidermotropic metastases arising in a congenital nevus. Am J Surg pathol 4(2):1783, 1980

    Google Scholar 

  254. Warren JS, Yum MN: Carcinoid tumor arising in a treated primary germ cell tumor of the mediastinum. South Med J 80(2):259–61, 1987

    PubMed  CAS  Google Scholar 

  255. Weiss RB, Klein MA: Non-Hodgkin’s lymphoma after successful therapy of small cell lung carcinoma. Cancer Chemother Pharmacol 14(1):9–11, 1985

    PubMed  CAS  Google Scholar 

  256. Wolberg WH, Tanner MA, Romsaas EP, et al: Factors influencing options in primary breast cancer treatment. J Clin Oncol 5(1):68–74, 1987

    PubMed  CAS  Google Scholar 

  257. Yamamoto Y, Moriwaki S, Takashima S, Yumoto Y: Autopsy case of simultaneous triple malignancies — ovarian, chordoma and thyroid cancers. Gan No Rinsho 29(11):1375–8, 1983

    PubMed  CAS  Google Scholar 

  258. Yock DH Jr: Choroid plexus lipomas associated with lipoma of the corpus callosum. J Comput Assist Tomogr 4(5):678–82, 1980

    PubMed  Google Scholar 

  259. Zarrabi MH, Rosner F, Grunwald HW: Second neoplasms in acute lymphoblastic leukemia. Cancer 52(9):1712–9, 1983

    PubMed  CAS  Google Scholar 

  260. Zucker PK, Berkowitz RS: The issue of microinvasive squamous cell carcinoma of the vulva: an evaluation of the criteria of diagnosis and methods of therapy. Obstet Gynecol Surv 40(3):136–43, 1985

    PubMed  CAS  Google Scholar 

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  1. Department of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, Md., USA

    Lance A. Liotta

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Kaiser, H.E. (1989). Multiple Primary Neoplasms. In: Liotta, L.A. (eds) Influence of Tumor Development on the Host. Cancer Growth and Progression, vol 3. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-2528-1_6

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