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Small intestine

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Clinical Investigations in Gastroenterology

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Abstract

The function of the small bowel can be evaluated by clinical tests of absorption (Chapter 6). Intestinal biopsy, bacteriology, radiology, radio-isotope studies and serology provide additional information to enable specific diagnoses to be made.

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References

  • Scott BB, Jenkins D. Endoscopic small intestinal biopsy. Gastrointest Endosc 1981; 27: 162–7

    Article  PubMed  CAS  Google Scholar 

  • Mee AS, Burke M, Vallon AG, Newman J, Cotton PB. Small bowel biopsy for malabsorption: comparison of the diagnostic adequacy of endoscopic forceps and capsule biopsy specimens. Br Med J 1985; 291: 769–72

    Article  CAS  Google Scholar 

  • Prout BJ. A rapid method of obtaining a jejunal biopsy using a Crosby capsule and gastrointestinal fibrescope. Gut 1974; 15: 571–2

    Article  PubMed  CAS  Google Scholar 

  • Evans N, Farrow LJ, Harding A, Stewart JS. New techniques for speeding small intestinal biopsy. Gut 1970; 11: 88–9

    Article  PubMed  CAS  Google Scholar 

  • Rachmilewitz D, Saunders DR. An improvement in the ease of passing a hydraulic biopsy tube. Gastroenterology 1975; 49: 571–2

    Google Scholar 

  • Crosby WH, Kugler HW. Intraluminal biopsy of the small intestine. Am J Dig Dis 1975; 2: 236–41

    Article  Google Scholar 

  • Bradborg LL, Rybin GE, Quinton WE. A multipurpose instrument for suction biopsy of the oesophagus, stomach, small bowel and colon. Gastroenterology 1959; 37: 1–16

    Google Scholar 

  • Flick AL, Quinton WE, Rubin CE. A personal hydraulic biopsy tube for multiple sampling at any level of the gastrointestinal tract. Gastroenterology 1961; 40: 120–6

    PubMed  CAS  Google Scholar 

  • Owen RL, Brandborg LL. Mucosal histopathology of malabsorption. Clin Gastroenterol 1983; 12: 575–90

    PubMed  CAS  Google Scholar 

  • Taylor RH, Waterman S. Single intubation test for investigation of malabsorption and diarrhoea. Gut 1983; 24: 680–2

    Article  PubMed  CAS  Google Scholar 

  • Linscheer WG, Abele JE. A new directable small bowel biopsy device. Gastroenterology 1976; 71: 575–6

    PubMed  CAS  Google Scholar 

  • Salter RH, Girdwood TG. Peroral jejunal biopsy with Watson capsule and Scott-Harden duodenal intubation tube. Lancet 1983; 2: 1460

    Article  PubMed  CAS  Google Scholar 

  • Whorwell PJ, Maxton DG, Martin DL. Post-colonoscopic retrograde ileography. Lancet 1988; 1: 738–9

    Article  PubMed  CAS  Google Scholar 

  • Hanser MF, Alderson PO. Gallium-67 imaging in abdominal disease. Semin Nucl Med 1982; 8: 251–70

    Google Scholar 

  • Holdstock G, Ligorria JE, Krawitt EL. Gallium-67 scanning in patients with Crohn’s disease: An aid to the diagnosis of abdominal abscess. Br J Surg 1982; 69: 277–8

    Article  PubMed  CAS  Google Scholar 

  • Rheingold OJ, Tedesco FJ, Block FE, Maldonado A, Miale A Jr. [67Ga] citrate scintiscanning in active inflammatory bowel disease. Dig Dis Sci 1979; 24: 363–8

    Article  PubMed  CAS  Google Scholar 

  • Saverymuttu SH, Peters AM, Lavender JP, Hodgson HJ, Chadwick VS. 111Indium autologous leukocytes in inflammatory bowel disease. Gut 1983; 24: 293–9

    Article  PubMed  CAS  Google Scholar 

  • Saverymuttu SH, Lavender JP, Hodgson HJF, Chadwick VS. Assessment of disease activity in inflammatory bowel disease: a new approach using 111indium in granulocyte scanning. Br Med J 1983; 287: 1751–3

    Article  CAS  Google Scholar 

  • Peters AM, Osman S, Henderson BL, Kelly JD, Danpure HJ, Hawker RJ, Hodgson HJ, Neirinckx RD. Clinical experience with 99mTc-hexamethylpropylene- amineoxime for labelling leukocytes and imaging inflammation. Lancet 1986; 25: 946–9

    Article  Google Scholar 

  • Dawson DJ, Khan AN, Miller V, Ratcliffe JF, Shreeve DR. Detection of inflammatory bowel disease in adults and children: evaluation of a new isotopic technique. Br J Med 1985; 291: 1227–30

    Article  CAS  Google Scholar 

  • Trotman IF, Price CC. Bloated irritable bowel syndrome defined by dynamic 99mTc bran scan. Lancet 1986; 364–7

    Google Scholar 

  • Walker-Smith JA, Skyring AP, Mistilis GP. Use of 51CrCl3 in the diagnosis of protein-losing enteropathy. Gut 1967; 8: 166–83

    Article  PubMed  CAS  Google Scholar 

  • Rubini ME, Sheahy TW. Exudative enteropathy. A comparative study of 51CrCl3 and 131I-PVP. J Lab Clin Med 1961; 58: 892–901

    PubMed  CAS  Google Scholar 

  • Waldman TA, Wocher RD, Strober W. The role of the gastrointestinal tract in plasma protein-metabolism studies with Cr-albumin. Am J Med 1969; 46: 275–85

    Article  Google Scholar 

  • Kerr RM, Dubois JJ, Holt PR. Use of the 125I-and 51Cr-labelled albumin for the measurement of gastrointestinal and total albumin catabolism. J Clin Invest 1967; 46: 2064–82

    Article  PubMed  CAS  Google Scholar 

  • Jarnum S, Westergaard H, Yssing M, Jensen H. Quantitation of gastrointestinal protein loss by means of 59Fe-labelled iron dextran. Gastroenterology 1968; 55: 229–41

    PubMed  CAS  Google Scholar 

  • Jarnum S, Jensen KB. Faecal radioiodine excretion following iv injection of 131I-albumin and 125I-immunoglobulin G in chronic inflammatory bowel disease. Gastroenterology 1975; 68: 1433–44

    PubMed  CAS  Google Scholar 

  • Crossley JR, Elliott RB. Simple method of diagnosing protein-loss enteropathies. Br Med J 1977; 1: 428–9

    Article  PubMed  CAS  Google Scholar 

  • Florent C, L’Hirondel C, Desmazures C, Aymes C, Bernier JJ. Intestinal clearance of 1-antitrypsin: a sensitive method for the detection of protein-losing enteropathy. Gastroenterology 1981; 81: 777–80

    PubMed  CAS  Google Scholar 

  • Goka AKJ, Rolston DDK, Mathan VI, Farthing MJG. Diagnosis of giardiasis by specific IgM antibody enzyme-linked immunosorbent assay. Lancet 1986; 2: 184–6

    Article  PubMed  CAS  Google Scholar 

  • Attwood SEA, Mealy K, Cafferkey MT, et al. Yersinia infection and acute abdominal pain. Lancet 1987; 1: 529–33

    Article  PubMed  CAS  Google Scholar 

  • Watson WS, Mckenzie I, Holden RI, Craig L, Sleight JD, Crean GP. An evaluation of the 14C-glycocholic acid breath test in the diagnosis of bacterial colonisation of the jejunum. Scottish Med J 1980; 25: 25–32

    Google Scholar 

  • James OFW, Agnew JE, Bouchier IAD. Assessment of the 14C-glycocholic acid breath test. Br Med J 1973; 3: 191–5

    Article  PubMed  CAS  Google Scholar 

  • Curzon G, Walsh J. A method for the determining of urinary indican. Clin Chem Acta 1962; 7: 657–63

    Article  CAS  Google Scholar 

  • King CE, Toskes PP. Small intestinal bacterial overgrowth. Gastroenterology 1979; 76: 1035–55 (review)

    PubMed  CAS  Google Scholar 

  • Mackowiak PA. The normal microbial flora. N Engl J Med 1982, 307: 83–93

    Article  PubMed  CAS  Google Scholar 

  • Hamilton I, Wolsey BW, Cobden I, Cooke EM, Shoesmith JG, Axon ATR. Simultaneous culture of saliva and jejunal aspirate in the investigation of small bowel bacterial overgrowth. Gut 1982; 23: 847–53

    Article  PubMed  CAS  Google Scholar 

  • Thompson DG, Binfield P, De Belder A, O’Brien J, Warren S, Wilson M. Extra-intestinal influences on exhaled breath hydrogen measurements during the investigation of gastrointestinal disease. Gut 1985; 26: 1349–52

    Article  PubMed  CAS  Google Scholar 

  • Gordts B, Hemelhof W, Retore P, Rahman M, Cadranel S, Butzler JP. Routine culture of giardia lamblia trophozoites from human duodenal aspirates. Lancet 1984; 2:137

    Article  PubMed  CAS  Google Scholar 

  • Levitt MD, Hirsch P, Fetzer CA, Sheaman M, Levine AS. H2 excretion after ingestion of complex carbohydrates. Gastroenterology 1987; 92: 383–9

    PubMed  CAS  Google Scholar 

  • Clarkson EM. A rapid method for the determination of chromium sesquioxide in faecal homogenates. Clin Chem Acta 1966; 16: 571–2

    Google Scholar 

  • Stanghellini V, Camilleri M, Malagelada J-R. Chronic idiopathic intestinal pseudo-obstruction (CIIP): Clinical and intestinal manometric findings. Gut 1987; 28: 5–12

    Article  PubMed  CAS  Google Scholar 

  • Kerlin P, Phillips S. Variability of motility of the ileum and jejunum in healthy humans. Gastroenterology 1982; 82: 694–700

    PubMed  CAS  Google Scholar 

  • Thompson DG, Wingate DL, Archer L, Benson MJ, Green WJ, Hardy RJ. Normal patterns of human upper small bowel activity recorded by prolonged radiotelemetry. Gut 1980; 21: 500–6

    Article  PubMed  CAS  Google Scholar 

  • Wald A, Van Thiel DH, Hoechstetter L. Gastrointestinal transit the effect of the menstrual cycle. Gastroenterology 1981; 80: 994–8

    Google Scholar 

  • McCrae S, Younger K, Thompson DG, Wingate DL. Sustained mental stress alters human jejunal motor activity. Gut 1982; 23: 404–9

    Article  Google Scholar 

  • Connel AM. Motility and its disturbances. Clin Gastroenterol 1982; 11: 437–686

    Google Scholar 

  • Holt G, Samuel E. Grey scale ultrasound in Crohn’s disease. Gut 1979; 20: 59–595

    Article  Google Scholar 

  • Harvey RF, Bradshaw IM. A simple index of Crohn’s disease activity. Lancet 1980; i: 514

    Article  Google Scholar 

  • Van Hees PAM, Van Elteren PH, Van Lier HJJ, Van Tongeren JHM. An index of inflammatory activity in patients with Crohn’s disease. Gut 1980; 21: 279–86

    Article  PubMed  Google Scholar 

  • Andre C, Descos L, Landais P, Fermanian J. Assessment of appropriate laboratory measurement to supplement the Crohn’s disease activity index. Gut 1981; 22: 571–4

    Article  PubMed  CAS  Google Scholar 

  • Brignola C, Campieri M, Bazzochi G, Farruggia P, Tragone A, Lan Franch EA. A laboratory index for predicting relapse in asymptomatic patients with Crohn’s disease. Gastroenterology 1986; 91: 1490–4

    PubMed  CAS  Google Scholar 

  • Miller A, Green M, Robinson D. Simple rule for calculating normal erythrocyte sedimentation rate. Br Med J 1983; 286: 266

    Article  CAS  Google Scholar 

  • Harries AD, Fitzsimons E, Fifield R, Dew MJ, Rhodes J. Platelet count: a simple measure of activity in Crohn’s disease. Br Med J 1983; 286: 1476

    Article  CAS  Google Scholar 

  • Admans H, Whorwell PJ, Wright R, Phil D. Diagnosis of Crohn’s disease. Dig Dis Sci 1980; 25: 911–15

    Article  PubMed  CAS  Google Scholar 

  • Chadwick VS. Diagnosis and medical management of Crohn’s disease. Br J Hosp Med 1982; 472–80

    Google Scholar 

  • Asmark E, Knutsson F, Thoren L. Phaeochromocytoma: diagnostic features. Acta Med Scand 1967; 182: 673–80

    Article  Google Scholar 

  • Mak M, Hallstrom O, Vesikari T, et al. Evaluation of serum IgA-class reticulin antibody. Test for the detection of childhood coeliac disease. J Paediatr 1984; 901–5

    Google Scholar 

  • Cacciari E, Salardi S, Volta U et al. Can antigliadin antibody detect symptomless coeliac disease in children with short stature? Lancet 1985; 1: 1469–71

    Article  PubMed  CAS  Google Scholar 

  • O’Farrelly C, Kelly J, Hekkens W et al. Alpha-gliadin antibodies: a serological test for coeliac disease. Br Med J 1983; 286: 2007–10

    Article  Google Scholar 

  • Savilahti E, Viander M, Perkkio M, Vainio E, Kalimo K, Reunala T. IgA antigliadin antibodies: a marker of mucosal damage in childhood coeliac disease. Lancet 1983; 1: 320–22

    Article  PubMed  CAS  Google Scholar 

  • Sivadasan K, Kurien B, John TJ. Rapid diagnosis of typhoid fever by antigen detection. Lancet 1984; 1: 134–5

    Article  PubMed  CAS  Google Scholar 

  • Belut D, Moneret-Vautrin DA, Nicholas JP, Grilliat JP. IgE levels in intestinal disease. J Dig Dis Sci 1980; 25: 323–32

    Article  CAS  Google Scholar 

  • Pearson DJ, Rix KJB, Bentley SJ. Food allergy: How much in the mind? A clinical and psychiatric study of suspected food hypersensitivity. Lancet 1983; 1: 1259–61

    Article  PubMed  CAS  Google Scholar 

  • Allun-Jones V, McLaughlan P, Shorthouse M, Workman E, Hunter JO. Food intolerance: a major factor in the pathogenesis of irritable bowel syndrome. Lancet 1982; 2: 1115–7

    Article  Google Scholar 

  • Whorwell PJ, Maxton DG, Martin DF. Post-colonoscopic retrograde ileography. Lancet 1988; 1: 729–738

    Google Scholar 

  • Aas K. Studies of hypersensitivity to fish-allergological and serological differentiation between various species of fish. Int Arch Allergy 1966; 30: 257

    Article  PubMed  CAS  Google Scholar 

  • Aas K. The diagnosis of hypersensitivity to ingested foods: reliability of skin prick testing and radioallergosorbent test with different materials. Clin Allergy 1978; 8: 39

    Article  PubMed  CAS  Google Scholar 

  • Maki M, Hallstrom O, Verronen P et al. Reticulin antibody, arthritis and coeliac disease in children. Lancet 1988; 1: 479–80

    Article  PubMed  CAS  Google Scholar 

  • Dias J, Unsworth DJ, Walker-Smith JA. Antigliadin and antireticulin antibodies in screening for coeliac disease. Lancet 1987; 2: 157–8

    Article  PubMed  CAS  Google Scholar 

  • Unsworth DJ, Walker-Smith JA, Holborow EJ. Gliadin and reticulin antibodies in childhool coeliac disease. Lancet 1983; 1: 874–5

    Article  PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Gastroenterology General Hospital, Bishop Auckland, County Durham, UK

    M. C. Bateson (Consultant Physician and Specialist)

  2. University of Edinburgh, UK

    I. A. Bouchier (Professor of Medicine)

Authors
  1. M. C. Bateson
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  2. I. A. Bouchier
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© 1988 Kluwer Academic Publishers

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Bateson, M.C., Bouchier, I.A. (1988). Small intestine. In: Clinical Investigations in Gastroenterology. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-2633-2_7

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  • DOI: https://doi.org/10.1007/978-94-009-2633-2_7

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-7688-3

  • Online ISBN: 978-94-009-2633-2

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