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The Renin-Angiotensin System

  • Chapter
Positron Emission Tomography: A Critical Assessment of Recent Trends

Part of the book series: NATO ASI Series ((ASHT,volume 51))

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Abstract

With an overall prevalence of 25 %, hypertension is a major public health problem. A direct link between arterial hypertension and cardiovascular events such as stroke and myocardial infarction has been clearly demonstrated although the pathogenesis of arterial hypertension is still not completely understood. Angiotensin receptors play a role, but this role could not be investigated in humans for a lack of appropriate noninvasive imaging techniques. This presentation describes how specific angiotensin antagonists can be used for investigation of the receptors in order to understand their physiology, pharmacology and regulation. It also gives clinical indications for future applications of PET imaging of these receptors.

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Authors and Affiliations

  1. The Johns Hopkins Medical Institutions, 600 North Wolfe Street, Baltimore, Maryland, 21205, USA

    Zsolt Szabo

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  1. Zsolt Szabo
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Editors and Affiliations

  1. Department of Neuroscience, Karolinska Institute, Stockholm, Sweden

    Balázs Gulyás

  2. Hungarian PET Foundation, Debrecen, Hungary

    Balázs Gulyás

  3. Institute for Medicine, Forschungszentrum Jülich GmbH, Jülich, Germany

    Hans W. Müller-Gärtner

  4. Department of Nuclear Medicine, Heinrich-Heine-University of Düsseldorf, Düsseldorf, Germany

    Hans W. Müller-Gärtner

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© 1998 Springer Science+Business Media Dordrecht

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Szabo, Z. (1998). The Renin-Angiotensin System. In: Gulyás, B., Müller-Gärtner, H.W. (eds) Positron Emission Tomography: A Critical Assessment of Recent Trends. NATO ASI Series, vol 51. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-4996-9_8

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  • DOI: https://doi.org/10.1007/978-94-011-4996-9_8

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