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Albumin

Engineering Applications

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Handbook of Biopolymers

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Abstract

Albumin is one of the most abundant plasma proteins found in recent times to possess multifunctionality. This chapter reveals the properties and engineering applications of albumin-based hydrogels influenced by chemical crosslinking, drug-coating techniques, pH, and thermal induction. To provide context, we first examine the nanotechnological techniques of developing albumin nanoparticles. Though albumin hydrogels generally find application in tissue engineering, they could also find usefulness for skin and wound healing, as well as toxicological studies involving stem cell-derived nerve cells, disease modeling, and drug delivery, when chemically cross-linked. This is because, cell survival and growth of chemically cross-linked albumin is possible, rather than when subjected to severe heat and acidic or alkaline conditions. Finally, albumin coatings via linkage engineering, electrostatic interactions, and electrostatic deposition are presented.

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Authors and Affiliations

  1. Chemical Engineering Department, University of Benin, Benin City, Nigeria

    Samuel Ogbeide Ebhodaghe

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  1. Samuel Ogbeide Ebhodaghe
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Correspondence to Samuel Ogbeide Ebhodaghe .

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Editors and Affiliations

  1. School of Chemical Science, Mahatma Gandhi University, Kottayam, India

    Sabu Thomas

  2. Mahatma Gandhi University, Kottayam, India

    Ajitha AR

  3. Department of Chemistry, Newman College, Thodupuzha, India

    Cintil Jose Chirayil

  4. Department of Chemistry, Newman College, Thodupuzha, India

    Bejoy Thomas

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Ebhodaghe, S.O. (2023). Albumin. In: Thomas, S., AR, A., Jose Chirayil, C., Thomas, B. (eds) Handbook of Biopolymers . Springer, Singapore. https://doi.org/10.1007/978-981-19-0710-4_31

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