Summary
In an ischemia-induced model of an acute motor neuron disorder, there is anterior horn cell damage with Wallerian degeneration in ventral roots; dorsal root ganglia and dorsal roots are unaffected. In a mixed nerve there is axonal degeneration reflecting loss of motor fibers. The sural nerve is normal showing that it does not contain motor fibers. This observation is relevant to the neuropathology of motor neuron disease where axonal degeneration found in the sural nerve suggests involvement of sensory fibers.
This is a preview of subscription content, log in via an institution to check access.
Explore related subjects
Discover the latest articles and news from researchers in related subjects, suggested using machine learning.References
Bradley WG, Good P, Rasool CG, Adelman LS (1983) Morphometric and biochemical studies of peripheral nerves in amyotrophic lateral sclerosis. Ann Neurol 14:267–277
Carpenter S, Karpati G, Rothman S, Watters G, Andermann F (1978) Pathological involvement of primary sensory neurons in Werdnig-Hoffmann disease. Acta Neuropathol (Berl) 42:91–97
Dyck JP, Karnes J, Lais A, Lofgren EP, Stevens JC (1984) Pathologic alterations of the peripheral nervous system of humans. In: Dyck PJ, Thomas PK, Lambert EH, Bunge R (eds) Peripheral neuropathy vol 1, 2nd edn. Saunders, Philadelphia
Dyck PJ, Stevens JC, Mulder DW, Espinosa RE (1975) Frequency of nerve fiber degeneration of peripheral motor and sensory neurons in amyotrophic lateral sclerosis. Neurology 25:781–785
Harrison LM (1975) Fiber diameter spectrum of the motor fibers of rat sural nerve. Exp Neurol 47:364–366
Nakanishi T, Norris FH (1970) Motor fibers in rat sural nerve. Exp Neurol 26:433–435
Zelena J, Hnik P (1963) Motor and receptor units in the soleus muscle after nerve regeneration in very young rats. Physiol Bochemoslov 12:277–289
Zivin JA, DeGirolami U, Hurwitz EL (1982) Spectrum of neurological deficits in experimental CNS ischemia. Arch Neurol 39:408–412
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Chad, D.A., DeGirolami, U. & Zivin, J. Motor fibers in the sural nerve. Acta Neuropathol 71, 338–340 (1986). https://doi.org/10.1007/BF00688059
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00688059