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A convenient synthesis of psoralen derivatives: Psoralen, 4-methyl-psoralen and 4-phenyl-psoralen

Ein Einfacher Syntheseweg zu Psoralen-Derivaten: Psoralen, 4-Methyl-psoralen und 4-Phenyl-Psoralen

  • Organische Chemie und Biochemie
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Abstract

A convenient synthesis of psoralen derivatives, viz., 7H-furo [3.2-g] [1] benzopyran-7-one (psoralen), 5-methyl-7H-furo [3.2-g] [1] benzopyran-7-one(4-methyl-psoralen) and 5-phenyl-7H-furo [3.2-g] [1] benzopyran-7-one-(4-phenyl-psoralen) by blocking the 8-position of the starting compounds with iodine, subsequentClaisen migration followed by cyclisation is described

Zusammenfassung

Zur Synthese der Titelverbindungen wird die 8-Position des als Ausgangsmaterial dienenden 7-Hydroxy-benzopyranons mit Jod blockiert, dann erfolgt Allylierung und nach einerClaisen-Wanderung die Cyclisierung.

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Authors and Affiliations

  1. Department of Chemistry, University of Delhi, 110007, Delhi, India

    V. K. Ahluwalin, Chandra Prakash & Shashi Bala

Authors
  1. V. K. Ahluwalin
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  2. Chandra Prakash
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  3. Shashi Bala
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Ahluwalin, V.K., Prakash, C. & Bala, S. A convenient synthesis of psoralen derivatives: Psoralen, 4-methyl-psoralen and 4-phenyl-psoralen. Monatshefte für Chemie 111, 877–882 (1980). https://doi.org/10.1007/BF00899252

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  • DOI: https://doi.org/10.1007/BF00899252

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