Abstract
His bundle pacing (HBP) preserves physiological ventricular synchrony, with clinical benefits particularly evident when a high percentage of ventricular pacing is required. First experiences with standard leads and manually shaped stylets produced the impression that HBP is highly complex and time-consuming. However, with dedicated leads and sheaths, reliable HBP can be achieved in routine clinical practice. Implantation success in more than 90% of patients can be reached with current technology and has been shown to be reliable and effective, both at implantation and during long-term follow-up. At the same time, fluoroscopy and total procedural time can be reduced. New customized technologies will continue to improve the implant success rate and system performance. Large randomized trials will prove the long-term clinical benefits of HBP definitively and may render HBP the first choice in patients requiring ventricular pacing.
Zusammenfassung
Die His-Bündel-Stimulation (HBS) bewahrt die physiologische Synchronität mit ihren klinischen Vorteilen, insbesondere bei Patienten, die einen hohen Anteil ventrikulärer Stimulation benötigen. Erste Erfahrungen mit Standardelektroden und manuell vorgebogenen Mandrins vermittelten den Eindruck, dass die HBS hochkomplex und zeitaufwendig wäre. Mit speziellen Elektroden und Schleusen kann jedoch eine zuverlässige His-Bündel-Stimulation auch in der klinischen Routine erreicht werden. Die derzeitige Technologie ermöglicht eine erfolgreiche Implantation bei mehr als 90 % der Patienten und hat sich als zuverlässig und effektiv erwiesen, sowohl bei der Implantation als auch im Langzeit-Follow-up. Gleichzeitig können die Fluoroskopie- und Prozedurgesamtdauer reduziert werden. Neue angepasste Technologien werden die Implantationserfolgsrate weiter steigern und die Systemfunktion optimieren. Große randomisierte Studien werden den klinischen Langzeitnutzen der HBS wohl definitiv nachweisen und könnten die HBS bei Patienten, die eine ventrikuläre Stimulation benötigen, zur Therapie der ersten Wahl machen.



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References
Kusumoto FM, Schoenfeld MH, Barrett C, Edgerton JR, Ellenbogen KA, Gold MR, Goldschlager NF, Hamilton RM, Joglar JA, Kim RJ, Lee R, Marine JE, McLeod CJ, Oken KR, Patton KK, Pellegrini C, Selzman KA, Thompson A, Varosy PD (2018) ACC/AHA/HRS guideline on the evaluation and management of patients with bradycardia and cardiac conduction delay: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society. Circulation 2019(140):e382–e482
Deshmukh P, Casavant DA, Romanyshyn M, Anderson K (2000) Permanent, direct His-bundle pacing: a novel approach to cardiac pacing in patients with normal His-Purkinje activation. Circulation 101(8):869–877
Vasquez P, Pichardo R, Gamero J, Saiz A, Lozano V, Fernandez J, Carranza M (2001) Estimulacion permanente del haz de His tras ablacion mediante radiofrequencia del nodo auriculoventricular en paziente con trastorno de la condution suprahisiano. Rev Esp Cardiol 54:1385–1393
Barba-Pichardo R, Morina-Vazquez P, Fernandez-Gomez JM, Venegas-Gamero J, Herrera-Carranza M (2010) Permanent His-bundle pacing: seeking physiological ventricular pacing. Europace 12:527–533
Deshmukh P, Romanyshyn M (2004) Direct His-bundle pacing: present and future. Pacing Clin Electrophysiol 27(Pt II):862–870
Occhetta E, Bortnik M, Magnani A et al (2006) Prevention of ventricular desynchronization by permanent para-Hisian pacing after atrioventricular node ablation in chronic atrial fibrillation: a crossover, blinded, randomized study versus apical right ventricular pacing. J Am Coll Cardiol 47:1938–1945
Gammage MD, Lieberman RA, Yee R, for the Worldwide SelectSecure Clinical Investigators et al (2006) Multi-Center clinical experience with a lumenless, catheter-delivered, bipolar, permanent pacemaker lead: Implant safety and electrical performance. Pacing Clin Electrophysiol 29:858–865
Zanon F, Ellenbogen KA, Dandamudi G, Sharma PS, Huang W, Lustgarten DL, Tung R, Tada H, Koneru JN, Bergemann T, Fagan DH, Hudnall JH, Vijayaraman P (2018) Permanent His-bundle pacing: a systematic literature review and meta-analysis. Europace 20(11):1819–1826
Zanon F, Baracca E, Aggio S et al (2006) A feasible approach for direct his-bundle pacing using a new steerable catheter to facilitate precise lead placement. J Cardiovasc Electrophysiol 17:29–33
Cantù F, De Filippo P, Cardano P et al (2006) Validation of criteria for selective His bundle and para-Hisian permanent pacing. Pacing Clin Electrophysiol 29:1326–1333
Zanon F, Abdelrahman M, Marcantoni L, Naperkowski A, Subzposh FA, Pastore G, Baracca E, Boaretto G, Raffagnato P, Tiribello A, Dandamudi G, Vijayaraman P (2019) Long term performance and safety of his bundle pacing: a multicenter experience. J Cardiovasc Electrophysiol 30(9):1594–1601
Vijayaraman P, Dandamudi G, Zanon F, Sharma PS, Tung R, Huang W, Koneru J, Tada H, Ellenbogen KA, Lustgarten DL (2018) Permanent His bundle pacing: recommendations from a Multicenter His Bundle Pacing Collaborative Working Group for standardization of definitions, implant measurements, and follow-up. Heart Rhythm 15(3):460–468
Jastrzębski M, Moskal P, Bednarek A, Kiełbasa G, Vijayaraman P, Czarnecka D (2019) Programmed His bundle pacing: a novel maneuver for the diagnosis of His bundle capture. Circ Arrhythm Electrophysiol 12(2):e7052
Vijayaraman P, Dandamudi G, Worsnick S, Ellenbogen KA (2015) Acute His-bundle injury current during permanent His-bundlepacing predicts excellent pacing outcomes. Pacing Clin Electrophysiol 38(5):540–546
Su L, Wu S, Wang S, Wang Z, Xiao F, Shan P, Zhou H, Huang Z, Xu L, Huang W (2019) Pacing parameters and success rates of permanent His-bundle pacing in patients with narrow QRS: a single-centre experience. Europace 1;21(5):763–770
Keene D, Arnold AD, Jastrzębski M, Burri H, Zweibel S, Crespo E, Chandrasekaran B, Bassi S, Joghetaei N, Swift M, Moskal P, Francis DP, Foley P, Shun-Shin MJ, Whinnett ZI (2019) His bundle pacing, learning curve, procedure characteristics, safety, and feasibility: Insights from a large international observational study. J Cardiovasc Electrophysiol 30(10):1984–1993
Beer D, Sharma PS, Subzposh FA, Naperkowski A, Pietrasik GM, Durr B, Qureshi M, Panikkath R, Abdelrahman M, Williams BA, Hanifin JL, Zimberg R, Austin K, Macuch B, Trohman RG, Vanenkevort EA, Dandamudi G, Vijayaraman P (2019) Clinical Outcomes of Selective Versus Nonselective His Bundle Pacing. JACC Clin Electrophysiol 5(7):766–774
Zanon F, Marcantoni L, Pastore G, Baracca G, Picariello C, Lanza D, Maddalozzo A, Giatti S, Carraro M, Roncon L, Barbetta A, Di Gregorio F (2019) The energy cost of His bundle pacing can be curtailed. Eur Heart J. https://doi.org/10.1093/eurheartj/ehz746.1137
Sharma PS, Huang HD, Trohman RG, Naperkowski A, Ellenbogen KA, Vijayaraman P (2019) Low Fluoroscopy Permanent His Bundle Pacing Using Electroanatomic Mapping: A Feasibility Study. Circ Arrhythm Electrophysiol 12(2):e6967
Zanon F, Marcantoni L, Zuin M, Pastore G, Baracca E, Tiribello A, Raffagnato P, Boaretto G, Roncon L, Vijayaraman P (2020) Electrogram-only guided approach to his bundle pacing with minimal fluoroscopy: a single-center experience. J Cardiovasc Electrophysiol. https://doi.org/10.1111/jce.14366
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L. Marcantoni received modest speaker fee (modest) from Abbott. F. Zanon received modest speaker fee (modest) from Abbott, Biotronik, Boston Scientific, Medtronic, Microport. M. Zuin, E. Baracca, G. Pastore, P. Raffagnato, A. Tiribello and G. Boaretto declare that they have no competing interests.
For this article no studies with human participants or animals were performed by any of the authors. All studies performed were in accordance with the ethical standards indicated in each case.
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Marcantoni, L., Zuin, M., Baracca, E. et al. Implantation technique of His bundle pacing. Herzschr Elektrophys 31, 111–116 (2020). https://doi.org/10.1007/s00399-020-00681-z
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DOI: https://doi.org/10.1007/s00399-020-00681-z