Abstract
The novel ionization technique of electrospray now allows the convenient mass spectrometric analysis of proteins and other biological molecules directly from liquids The molecular weights of protein can be determined to better than 0.01 per cent mass accuracy.
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References
Karas, M. & Hillenkamp, F. Analyt. Chem. 60, 2299–2301 (1988).
Meng, C.K., Mann, M. & Fenn, J.B. Phys. D10, 361–368 (1988).
Fenn, J.B., Mann, M., Meng, C.K., Wong, S.F. & White-house, C.M. Mass Spectrom. Rev. 9, 37–70 (1990).
Smith, R.D., Loo, J.A., Edmonds, C.G., Barinaga, C.J. & Udseth, H.R. Analyt. Chem. 62, 882–899 (1990).
Whitehouse, C.M., Dreyer, R.N., Yamishita, M. & Fenn, J.B. Analyt. Chem. 57, 675–679 (1985).
Lee, E.D., Henion, J.D. & Covey, T.R. J. Microcol.Sep. 1, 14–18 (1989).
Smith, R.D., Barinaga, C.J. & Udseth, H.R. Analyt. Chem. 60, 1948–1952 (1988).
Burlingame, A.L., Maltby, D., Russell, D.H. & Holland, P. T. Analyt. Chem. 60, 294R–342R (1988).
Loo, J.A., Edmonds, C.G. & Smith, R.D. Science 248, 201–204 (1990).
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Jardine, I. Electrospray ionization mass spectrometry of biomolecules. Nature 345, 747–748 (1990). https://doi.org/10.1038/345747a0
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DOI: https://doi.org/10.1038/345747a0
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