Abstract
IN view of the possibility that prostaglandins (PG) regulate local blood flow1, we are investigating this activity in the pancreas. We have already found that PGE2 reduces vascular resistance in the perfused rat pancreas whereas PGF2α has the opposite effect2. These effects were seen at low doses (0.1 µg/ml.) and with good reproducibility.
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References
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SAUNDERS, R., MOSER, C. Increased Vascular Resistance by Prostaglandins B1 and B2 in the Isolated Rat Pancreas. Nature New Biology 237, 285 (1972). https://doi.org/10.1038/newbio237285a0
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DOI: https://doi.org/10.1038/newbio237285a0
