High-throughput sequencing of massive mutant libraries helps researchers catalog determinants of protein stability.
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References
Kim, I. et al. High-throughput analysis of in vivo protein stability. Mol. Cell. Proteomics doi:10.1074/mcp.O113.031708 (29 July 2013).
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Eisenstein, M. Self-destruct sequences. Nat Methods 10, 935 (2013). https://doi.org/10.1038/nmeth.2678
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DOI: https://doi.org/10.1038/nmeth.2678