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Dementia

Depression and dementia

Nature Reviews Neurology volume 6, page 470 (2010)Cite this article

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Two studies published recently in Neurology have further clarified the link between depression and dementia—identified by previous research—by following large population-based samples over long follow-up periods.

In a 17 year follow-up, Jane Saczynski and colleagues found that depression at baseline was associated with a >50% increase in dementia risk. Vonetta Dotson and colleagues showed that dementia risk increased with the number of episodes of elevated depressive symptoms (EDS) experienced by individuals over a period of nearly 25 years.

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ORIGINAL RESEARCH PAPERS

  1. Dotson, V. M. et al. Recurrent depressive symptoms and the incidence of dementia and mild cognitive impairment. Neurology 75, 27–34 (2010)

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  2. Saczynski, J. S. et al. Depressive symptoms and risk of dementia: the Framingham Heart Study. Neurology 75, 35–41 (2010)

    Article  CAS  Google Scholar 

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  1. Eleanor Beal
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Beal, E. Depression and dementia. Nat Rev Neurol 6, 470 (2010). https://doi.org/10.1038/nrneurol.2010.123

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  • DOI: https://doi.org/10.1038/nrneurol.2010.123

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