The neural mechanisms of many symptoms associated with migraine have yet to be elucidated. New research suggests that a non-image-forming retinal pathway and signals from the dura mater contribute to photophobia in patients with migraine. More research is needed to understand the mechanisms behind other migraine-associated symptoms such as nausea and osmophobia.
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Olesen, J. A neural pathway for photophobia in migraine. Nat Rev Neurol 6, 241–242 (2010). https://doi.org/10.1038/nrneurol.2010.50
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DOI: https://doi.org/10.1038/nrneurol.2010.50