Abstract:
Restriction mapping is a process by which sites along an unsequenced DNA molecule are located through measurement of the distance between them. The authors consider a mod...Show MoreMetadata
Abstract:
Restriction mapping is a process by which sites along an unsequenced DNA molecule are located through measurement of the distance between them. The authors consider a model for handling errors in restriction maps in which the error in measurement is modeled by using a normal distribution. Minimum message length techniques are applied to evaluate the relative merit of competing solutions to a restriction mapping problem. This is simplified, for cases where the cost of the model is equivalent, to a maximum likelihood criterion, which is used to rank multiple solutions by considering each arrangement as a different hypothesis.<>
Published in: [1993] Proceedings of the Twenty-sixth Hawaii International Conference on System Sciences
Date of Conference: 08-08 January 1993
Date Added to IEEE Xplore: 09 July 2003
Print ISBN:0-8186-3230-5