Your privacy, your choice

We use essential cookies to make sure the site can function. We also use optional cookies for advertising, personalisation of content, usage analysis, and social media.

By accepting optional cookies, you consent to the processing of your personal data - including transfers to third parties. Some third parties are outside of the European Economic Area, with varying standards of data protection.

See our privacy policy for more information on the use of your personal data.

for further information and to change your choices.
Skip to main content
Download PDF

Correction: Aloe-emodin inhibits African swine fever virus replication by promoting apoptosis via regulating NF-κB signaling pathway

Virology Journal volume 22, Article number: 60 (2025) Cite this article

The Original Article was published on 19 July 2023

Correction to: Virology Journal (2023) 20:158 https://doi.org/10.1186/s12985-023-02126-8

In this article [1], Fig(s) 4 and 5 appeared incorrectly and have now been corrected in the original publication. For completeness and transparency, both the incorrect and correct versions are displayed below.

Incorrect Figs. 4 and 5

Fig. 4
figure a

Ae inhibits the NF-κB signaling pathway activated by ASFV infection. The expression level of (A) MyD88 protein, (B) phospho-NF-κB p65 protein, and (C) pIκB protein in the ASFV-infected group, ASFV-infected group treated with BAY11-7082 or Ae was detected by western blot. The expression of tubulin was used as a positive control. qPCR was used to detect the changes of (D) IL-1β mRNA levels and (E) IL-8 mRNA levels in the ASFV-infected group, ASFV-infected group treated with BAY11-7082, or Ae at different time points. The mRNA level of GAPDH was used as a positive control. All control cells were normal cultured PAMs. The results of three independent experiments (mean ± SD) were represented by one data. Significant differences that were compared to the control group were indicated by * (P < 0.05), ** (P < 0.01) and *** (P < 0.001)

Full size image
Fig. 5
figure b

Ae promotes apoptosis by inhibiting the NF-κB signaling pathway. (A) The apoptosis of PAMs in the ASFV infection group, BAY11-7082 or Ae-treated ASFV infection group was detected by flow cytometry, and the apoptosis of induced cells was detected at 3, 12 and 48 h after treatment. Untreated cells served as negative controls. The expression level of (B) Bcl-2 protein, (C) cleaved-caspase3 protein, and (D) Bax protein in the ASFV infection group, BAY11-7082 or Ae-treated ASFV infection group was detected by western blot. All control cells were normal cultured PAMs. The tubulin expression was used as a positive control

Full size image

Correct Figs. 4 and 5

Fig. 4
figure 1

Ae inhibits the NF-κB signaling pathway activated by ASFV infection. A The expression level ofMyD88 protein, phospho-NF-κB p65 protein, and pIκB protein in the ASFV-infected group, ASFV-infected group treated with BAY11-7082 or Ae was detected by western blot. The expression of tubulin was used as a positive control. qPCR was used to detect the changes of B IL-1β mRNA levels and C IL-8 mRNA levels in the ASFV-infected group, ASFV-infected group treated with BAY11-7082, or Ae at different time points. The mRNA level of GAPDH was used as a positive control. All control cells were normal cultured PAMs. The results of three independent experiments (mean ± SD) were represented by one data. Significant differences that were compared to the control group were indicated by * (P < 0.05), ** (P < 0.01) and *** (P < 0.001)

Full size image
Fig. 5
figure 2

Ae promotes apoptosis by inhibiting the NF-κB signaling pathway. A The apoptosis of PAMs in the ASFV infection group, BAY11-7082 or Ae-treated ASFV infection group was detected by flow cytometry, and the apoptosis of induced cells was detected at 3, 12 and 48 h after treatment. Untreated cells served as negative controls. The expression level of B Bcl-2 protein, cleaved-caspase3 protein, and Bax protein in the ASFV infection group, BAY11-7082 or Ae-treated ASFV infection group was detected by western blot. All control cells were normal cultured PAMs. The tubulin expression was used as a positive control

Full size image

Reference

  1. Luo Y, Yang Y, Wang W, et al. Aloe-emodin inhibits African swine fever virus replication by promoting apoptosis via regulating NF-κB signaling pathway. Virol J. 2023;20:158. https://doi.org/10.1186/s12985-023-02126-8.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Key Laboratory of Zoonosis Prevention and Control of Guangdong Province, College of Veterinary Medicine, South China Agricultural University, Guangzhou, 510462, China

    Yizhuo Luo, Yunlong Yang, Wenru Wang, Qi Gao, Ting Gong, Yongzhi Feng, Dongdong Wu, Xiaoyu Zheng, Guihong Zhang & Heng Wang

  2. African Swine Fever Regional Laboratory of China (Guangzhou), Guangzhou, 510642, China

    Yizhuo Luo, Yunlong Yang, Qi Gao, Guihong Zhang & Heng Wang

  3. Key Laboratory of Animal Vaccine Development, Ministry of Agriculture and Rural Affairs, Guangzhou, PR China

    Yizhuo Luo, Guihong Zhang & Heng Wang

  4. Maoming Branch, Guangdong Laboratory for Lingnan Modern Agriculture, Maoming, 525000, China

    Qi Gao, Yongzhi Feng, Xiaoyu Zheng, Guihong Zhang & Heng Wang

  5. Research Center for African Swine Fever Prevention and Control, South China Agricultural University, Guangzhou, 510642, China

    Ting Gong, Dongdong Wu, Guihong Zhang & Heng Wang

Authors
  1. Yizhuo Luo
    View author publications

    You can also search for this author inPubMed Google Scholar

  2. Yunlong Yang
    View author publications

    You can also search for this author inPubMed Google Scholar

  3. Wenru Wang
    View author publications

    You can also search for this author inPubMed Google Scholar

  4. Qi Gao
    View author publications

    You can also search for this author inPubMed Google Scholar

  5. Ting Gong
    View author publications

    You can also search for this author inPubMed Google Scholar

  6. Yongzhi Feng
    View author publications

    You can also search for this author inPubMed Google Scholar

  7. Dongdong Wu
    View author publications

    You can also search for this author inPubMed Google Scholar

  8. Xiaoyu Zheng
    View author publications

    You can also search for this author inPubMed Google Scholar

  9. Guihong Zhang
    View author publications

    You can also search for this author inPubMed Google Scholar

  10. Heng Wang
    View author publications

    You can also search for this author inPubMed Google Scholar

Corresponding author

Correspondence to Heng Wang.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Luo, Y., Yang, Y., Wang, W. et al. Correction: Aloe-emodin inhibits African swine fever virus replication by promoting apoptosis via regulating NF-κB signaling pathway. Virol J 22, 60 (2025). https://doi.org/10.1186/s12985-025-02676-z

Download citation

  • Published:

  • DOI: https://doi.org/10.1186/s12985-025-02676-z

Virology Journal

ISSN: 1743-422X