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Novel Etoposide Analogue Modulates Expression of Angiogenesis Associated microRNAs and Regulates Cell Proliferation by Targeting STAT3 in Breast Cancer

Fig 5

Caspase-9 assay.

(A and B) Apoalert Caspase-9 fluorescent assay showing the apoptotic inducing ability of Etoposide or C-10 separately and in combination with miR-15, 16, 17 and 221. Results represent mean ± SD of three independent experiments. * represents p-value < 0.05, ** represents p-value < 0.01 and *** represents p-value < 0.001.

Fig 5

doi: https://doi.org/10.1371/journal.pone.0142006.g005