Published March 10, 2019 | Version v1
Journal article Open

AN ASSESSMENT OF OCULAR ETIOLOGICAL FACTORS, COMPLICATIONS AND MANIFESTATION AMONG RESTLESS TOXIC EPIDERMAL NECROLYSIS/ STEVENS-JOHNSON SYNDROME PATIENTS

Description

Objective: The objective of the study was to explain the ocular demonstrations of Stevens-Johnson Syndrome/Toxic epidermal necrolysis among restless patients at a tertiary care Hospital.

Methods: This research study was conducted at Sir Ganga Ram Hospital, Lahore (February to December 2017), patients were detected with Stevens-Johnson Syndrome/Toxic epidermal necrosis. The information was assembled for these patients regarding age, gender, causes and ocular results. To analyses data statically, SPSS was employed.

Results: Total patients selected for this study were 87. The number of male patients was 48 (55.2%). The age bracket for these patients was between 1 month to 84 years. The mean age was (33.2 ± 22.2) years. Idiopathic, non-steroidal inflammatory drugs and anti-epileptics were the common reasons. These reasons were observed in 20 (23%) and 11 (12.6%) respectively. Because of minor conjunctival adhesions, glass Roding was carried out in 16 (18.4%) patients. Moreover, ocular involvement was observed in 45 (51.7%), genital-mucosal involvement was observed in 27 (31.0%) and mucosal participation was observed in 34 (96.6%) patients.

Conclusion: There was a common ocular demonstration of different extremity. The most obvious cause was drugs.

Keywords: Stevens-Johnson Syndrome, Toxic Epidermal Necrolysis, Ocular Manifestations, Etiology.

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