Hyperuricemia and hypertension

Rapicka Dorota, Fabian-Danielewska Anna. Hyperuricemia and hypertension. Journal of Education, Health and Sport. 2019;9(7):233-239. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.3269865

http://ojs.ukw.edu.pl/index.php/johs/article/view/7124

https://pbn.nauka.gov.pl/sedno-webapp/works/917534

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© The Authors 2019;

This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland

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Received: 20.06.2019. Revised: 25.06.2019. Accepted: 05.07.2019.

Hyperuricemia and hypertension

Dorota Rapicka¹, Anna Fabian-Danielewska^1,2

1. NZOZ Przychodnia Medycyny Rodzinnej, ul. Kadłubka 10-11, Szczecin

2. Pomeranian Medical University in Szczecin, PhD study at the Faculty of Medicine

Summary

Hiperuricemia is associated mostly with gout and urolithiasis. However, it is now known that it affects a number of other health problems. It plays an important role in the development of hypertension, metabolic syndrome and other cardiovascular diseases. In addition, the relationship between hyperuricemia and obesity, hyperlipidemia, stroke and vascular dementia, renal disease, obstructive sleep apnea and insulin resistance has been proven. Increased serum uric acid is a risk factor for cardiovascular disease and contributes to increased mortality in patients with ischemic heart disease. The preferred drugs for the treatment of hypertension with increased uric acid concentration are calcium channel blockers (urinary properties) and losartan. From diuretics aldosterone antagonists are prefered. Other blockers of the angiotensin receptor should be avoided because they reduce the excretion of uric acid by the kidneys. B-blockers, thiazide and loop diuretics, ACE inhibitors are also inadvisable.

Key words: hyperuricemia; uric acid; gout; hypertension; metabolic syndrome; cardiovascular diseases