THE REACTION OF O-METHYLISOUREA WITH BOVINE PANCREATIC RIBONUCLEASE
Werner A. Klee, Frederic M. Richards
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Kinetic and thermodynamic analysis of the conformational folding process of SS‐reduced bovine pancreatic ribonuclease A using a selenoxide reagent with high oxidizing ability [PDF]
Kenta Arai+2 more
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Production of ovine Pancreatic Ribonuclease and investigation of enzyme characteristics [PDF]
Introduction Obviously, the recent decades strategy in cancer therapy, anticancer drug discovery and drug improvement is to characterize, distinguish and validate the most promising cancer-related molecular targets to which new drugs can be designed. The
mahsa Zabetian+3 more
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Ribonucleases as potential therapeutic agents [PDF]
Objective Due to high cytotoxicity effect, ribonucleases (RNases) are known as pharmacological agents with therapeutic potential. The high potential of these enzymes in the destruction of RNA strand and their other substrates and subsequently, cell ...
Masoume Vakili-Azghandi+3 more
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Extraction and Chromatography of Mouse and Bovine Pancreatic Ribonucleases
Sherman R. Dickman+2 more
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Engineering and production of recombinant bovine pancreatic ribonuclease enzyme (RNase A) as a potential therapeutic [PDF]
Objective Immunotoxins are one of the most promising ways in therapeutic fields, specially cancer therapy which have a unique toxin-antibody structure, and kill the cancer cell by passing through the cell membrane and entering the target cell.
Masoume Vakili-Azghandi+3 more
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PEGylated gold nanoparticles-ribonuclease induced oxidative stress and apoptosis in colorectal cancer cells [PDF]
Introduction: Currently, drug-induced reactive oxygen species (ROS) mediating apoptosis pathway have extensively been investigated in designing effective strategies for colorectal cancer (CRC) chemotherapy.
Mostafa Akbarzadeh Khiavi+7 more
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Bovine Pancreatic RNase A: An Insight into the Mechanism of Antitumor Activity In Vitro and In Vivo
In this investigation, we extensively studied the mechanism of antitumor activity of bovine pancreatic RNase A. Using confocal microscopy, we show that after RNase A penetration into HeLa and B16 cells, a part of the enzyme remains unbound with the ...
Islam Saber Ead Mohamed+6 more
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A Comparative Study of the Structures of Bovine and Ovine Pancreatic Ribonucleases
Christian B. Anfinsen+3 more
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Oxidative protein folding involves the formation of disulfide bonds and the regeneration of native structure (N) from the fully reduced and unfolded protein (R).
Mahesh Narayan
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