Results 11 to 20 of about 84,773 (249)

Viral Hepatitis and Rapid Diagnostic Test Based Screening for HBsAg in HIV-infected Patients in Rural Tanzania. [PDF]

, 2013
\ud \ud Co-infection with hepatitis B virus (HBV) is highly prevalent in people living with HIV in Sub-Saharan Africa. Screening for HBV surface antigen (HBsAg) before initiation of combination antiretroviral therapy (cART) is recommended. However, it is
AM Geretti, AP Kourtis, AS Lok, Bernadeta Msongole, BH Tess, Bruno Verhasselt, Christoph Hatz, CJ Hoffmann, CJ Hoffmann, CL Thio, D Nash, E Mossdorf, E Stahel, ED Chan, Emilio Letang, F Randrianirina, Fabian C. Franzeck, Geoffrey Mwaigomole, GV Matthews, J Davies, J Jaroszewicz, J Li, L Martin-Carbonero, L Stabinski, Lars Henning, M Nyirenda, MA Thompson, Manuel Battegay, Marcel Tanner, Marian Hamisi, MC Kew, Omary Abdul, PM Bossuyt, R Weber, Ramadhani Ngwale, TEMS de Vries–Sluijs, TJ Nagu   +36 more
core   +20 more sources

Tenofovir Alafenamide Fumarate Reduces Virological Replication in HBeAg-Negative Patients With Normal Alanine Aminotransferase: A 48-Week Randomised Controlled Trial. [PDF]

J Viral Hepat
ABSTRACT The optimal strategy for chronic hepatitis B virus (HBV) infected patients with negative hepatitis B e‐antigen (HBeAg) and normal alanine aminotransferase (ALT) remains uncertain. This study aimed to evaluate the safety and efficacy of tenofovir alafenamide fumarate (TAF) treatment in this patient population.
Luo Q, Xu W, Zhang Y, Li X, Lai J, Li J, Zheng X, Deng H, Chen L, Zhu X, Xie C, Peng L.   +11 more
europepmc   +2 more sources

SERUM HSP 70 LEVELS OF CHRONIC HEPATITIS B PATIENTS ARE SUBSTANTIALLY CORRELATED WITH HBsAg [PDF]

Euromediterranean Biomedical Journal, 2020
Heat-shock protein 70 (HSP70) is a stress-induced protein that demonstrates the anti-apoptosis response that ensures the survival of cells. The aim of this study is to investigate the significant correlation of serum HSP70 levels in chronic hepatitis B ...
Awaz Saadi
doaj   +1 more source

Characteristics analysis of HBV serological markers of NAT reactive blood donors under different HBsAg status

Zhongguo shuxue zazhi, 2023
Objective To investigate the characteristics of HBV serological markers of NAT reactive blood donors under different HBsAg status. Methods NAT reactive samples, with HBsAg-, HBsAg+ /retest - and HBsAg+ by single reagent were collected from September 2021
Dequn NI, Tingting WANG, Ting WANG, Mingrui LI, Weiya CUI, Xin XIE, Qing HE, Suping LI   +7 more
doaj   +1 more source

The role of Recombinant interleukin-2 in the treatment of patients with chronic hepatitis B.

Инфекция и иммунитет, 2023
Dysregulated immune response occurring in chronic hepatitis B prevents the virus elimination and contributes to progression of the infectious process.
Anastasiya F. Novikova, Larisa L. Popova, Dmitrii Yu. Konstantinov   +2 more
doaj   +1 more source

Efficient conjugation of anti-HBsAg antibody to modified core-shell magnetic nanoparticles (Fe3O4@SiO2/NH2) [PDF]

BioImpacts, 2021
Introduction: Further development of magnetic-based detection techniques could be of significant use in increasing the sensitivity of detection and quantification of hepatitis B virus (HBV) infection.
Shahram Parvaneh, Fatemeh Khademi, Gisya Abdi, Abdolhamid Alizadeh, Ali Mostafaie   +4 more
doaj   +1 more source

High Prevalence of Active HDV Infection Among HBsAg-Positive Patients in Urban and Rural Areas in Gabon: A Cross-Sectional Retrospective Study. [PDF]

Health Sci Rep
ABSTRACT Background HDV, a defective virus dependent on hepatitis B for assembly, can lead to severe liver diseases and an increased risk of progressing to complications such as hepatocellular carcinoma. Given the high prevalence of HDV in Gabon, especially in central Africa, understanding the epidemiology and associated risks is crucial.
Bivigou-Mboumba B, Bignoumba M, Moussavou-Boundzanga P, Missoni Manga EL, Gafou A, Mouanga Ndzime Y, Wora DM, Akombi LF, Olembi JLZ, Ndjila RMB, Bisseye C, Mouinga Ondeme A, Onanga R, Pineau P.   +13 more
europepmc   +2 more sources

Performance Evaluation of an Improved HBsAg Assay (HBsAg NEXT) for the Detection of HBsAg Levels

Journal of Laboratory Physicians, 2023
Abstract Objectives Detection of hepatitis B surface antigen (HBsAg) plays an important role in the screening and diagnosis of hepatitis B virus (HBV) infections. There is a need of highly sensitive assays with an improved lower limit of detection (LoD).
Ekta Gupta, Arjun Bhugra, Jasmine Samal, Arvind Khodare, Keshaw Singh, Aayushi Rastogi, Manoj Kumar Sharma   +6 more
openaire   +2 more sources

Mitochondrial stress in advanced fibrosis and cirrhosis associated with chronic hepatitis B, chronic hepatitis C, or nonalcoholic steatohepatitis

Hepatology, EarlyView., 2022
Adaptive mitochondrial mechanisms allow mitochondrial resilience and prevent the worsening of fibrosis, while deregulation of these mechanisms promotes the progression from no/minimal‐mild (F0‐F2) fibrosis to advanced fibrosis and cirrhosis (F3‐F4). Abstract Background and Aims Hepatitis B virus (HBV) infection causes oxidative stress (OS) and alters ...
Dimitri Loureiro, Issam Tout, Stéphanie Narguet, Cheikh Mohamed Bed, Morgane Roinard, Ahmad Sleiman, Nathalie Boyer, Nathalie Pons‐Kerjean, Corinne Castelnau, Nathalie Giuly, Dorothy Tonui, Vassili Soumelis, Jamel El Benna, Patrick Soussan, Richard Moreau, Valérie Paradis, Abdellah Mansouri, Tarik Asselah   +17 more
wiley   +1 more source

A Systematic Review and Model-Based Meta-Analysis of Pegylated-Interferon-α-Induced HBsAg Loss in Chronic Hepatitis B Virus Infection. [PDF]

CPT Pharmacometrics Syst Pharmacol
ABSTRACT Pegylated‐interferon‐α (Peg‐IFNα) is a treatment option for chronic hepatitis B virus (HBV) infection. To quantify treatment response variability, we conducted a model‐based meta‐analysis (MBMA) of hepatitis B surface antigen (HBsAg) loss, defined as a binary outcome based on HBsAg levels falling below the limit of detection, with Peg‐IFNα ...
Hanan NJ, Zierhut ML, Nader A, Mahajan A, Kaur A, Kumar K, Dixon SA, Das J, Magee M, Theodore D, Gielen V.   +10 more
europepmc   +2 more sources