Results 11 to 20 of about 13,346,118 (274)

Hereditary Prostate Cancer: Genes Related, Target Therapy and Prevention

International Journal of Molecular Sciences, 2021
Prostate cancer (PCa) is globally the second most diagnosed cancer type and the most common cause of cancer-related deaths in men. Family history of PCa, hereditary breast and ovarian cancer (HBOC) and Lynch syndromes (LS), are among the most important ...
M. Vietri, Giovanna D’Elia, Gemma Caliendo, M. Resse, A. Casamassimi, L. Passariello, Luisa Albanese, M. Cioffi, A. Molinari   +8 more
semanticscholar   +1 more source

A systematic review of clinical studies on hereditary factors in pelvic organ prolapse

International Urogynecology Journal, 2012
Introduction and hypothesisThere is growing evidence that pelvic organ prolapse (POP) is at least partly caused by underlying hereditary risk factors.
S. Lince, L. V. van Kempen, M. Vierhout, K. Kluivers   +3 more
semanticscholar   +1 more source

Identification of a Comprehensive Spectrum of Genetic Factors for Hereditary Breast Cancer in a Chinese Population by Next-Generation Sequencing

PLoS ONE, 2015
The genetic etiology of hereditary breast cancer has not been fully elucidated. Although germline mutations of high-penetrance genes such as BRCA1/2 are implicated in development of hereditary breast cancers, at least half of all breast cancer families ...
Xiaochen Yang, Jiong Wu, Jin‐song Lu, Guangyu Liu, G. Di, Can-ming Chen, Yifeng Hou, Menghong Sun, Wentao Yang, Xiaojin Xu, Ying Zhao, Xin Hu, Da-Qiang Li, Z. Cao, Xiaoyan Zhou, Xiao-yan Huang, Zhe-bin Liu, Huan Chen, Yanzi Gu, Y. Chi, Xiangang Yan, Q. Han, Z. Shen, Z. Shao, Zhen Hu   +24 more
semanticscholar   +1 more source

Hereditary Factor X (Stuart-Prower Factor) Deficiency [PDF]

Medical Journal Armed Forces India, 2008
Inherited deficiency of Factor X was first reported way back in mid 1950s by workers who were studying patients with a haemorrhagic disease resembling factor VII deficiency. It is also known by the surnames of the patients who were first found to manifest the defect (Stuart and Prower).
P K, Gupta, H, Kumar, S, Kumar
openaire   +2 more sources

Epidemiology of colorectal cancer: incidence, mortality, survival, and risk factors

Gastroenterology Review, 2019
According to GLOBOCAN 2018 data, colorectal cancer (CRC) is the third most deadly and fourth most commonly diagnosed cancer in the world. Nearly 2 million new cases and about 1 million deaths are expected in 2018.
Prashanth Rawla, T. Sunkara, Adam Barsouk   +2 more
semanticscholar   +1 more source

Risk of angioedema following invasive or surgical procedures in HAE type I and II : the natural history [PDF]

, 2013
Background: Hereditary angioedema (HAE), caused by deficiency in C1-inhibitor (C1-INH), leads to unpredictable edema of subcutaneous tissues with potentially fatal complications.
Aygören-Pürsün, Emel, Klingebiel, Thomas, Kreuz, Wolfhart, Martinez Saguer, Inmaculada, Schwabe, Dirk   +4 more
core   +1 more source

Guidelines for the management of hereditary colorectal cancer from the British Society of Gastroenterology (BSG)/Association of Coloproctology of Great Britain and Ireland (ACPGBI)/United Kingdom Cancer Genetics Group (UKCGG)

Gut, 2019
Heritable factors account for approximately 35% of colorectal cancer (CRC) risk, and almost 30% of the population in the UK have a family history of CRC.
K. Monahan, Nicola Bradshaw, Sunil Dolwani, B. Desouza, Malcolm G. Dunlop, J. East, Mohammad Ilyas, A. Kaur, F. Lalloo, A. Latchford, M. D. Rutter, I. Tomlinson, Huw J W Thomas, James Hill   +13 more
semanticscholar   +1 more source

WAO guideline for the management of hereditary angioedema [PDF]

, 2012
Hereditary Angioedema (HAE) is a rare disease and for this reason proper diagnosis and appropriate therapy are often unknown or not available for physicians and other health care providers.
Aygören-Pürsün, Emel, Bork, Konrad, Bowen, Tom, Boysen, Henrik B., Craig, Timothy, Farkas, Henriette, Grumach, Anete, Katelaris, Constance H., Lockey, Richard, Longhurst, Hilary, Lumry, William, Magerl, Markus, Martinez-Saguer, Immaculada, Maurer, Marcus, Nast, Alexander, Pawankar, Ruby, Ritchie, Bruce, Zuraw, Bruce   +17 more
core   +1 more source

The roles of endoglin gene in cerebrovascular diseases. [PDF]

, 2017
Endoglin (ENG, also known as CD105) is a transforming growth factor β (TGFβ) associated receptor and is required for both vasculogenesis and angiogenesis.
Ma, Li, Su, Hua, Zhang, Rui, Zhu, Wan
core   +2 more sources

Multi-gene panel testing for hereditary cancer predisposition in unsolved high-risk breast and ovarian cancer patients. [PDF]

, 2017
PurposeMany women with an elevated risk of hereditary breast and ovarian cancer have previously tested negative for pathogenic mutations in BRCA1 and BRCA2. Among them, a subset has hereditary susceptibility to cancer and requires further testing.
Adams, Sophie B, Chan, Salina, Crawford, Beth, Gil, Elad, Leitner, Ofri, Ryan, Lauren, Sittler, Taylor, van 't Veer, Laura, van den Akker, Jeroen   +8 more
core   +1 more source