Results 11 to 20 of about 857,514 (313)

Progress of small ubiquitin-related modifiers in kidney diseases

open access: yesChinese Medical Journal, 2019
. Objective:. Small ubiquitin-related modifiers (SUMOs) are a group of post-translational modification proteins extensively expressed in eukaryotes. Abnormal SUMOylation can lead to the development of various diseases.
Ou Li   +6 more
doaj   +1 more source

The PI3K-Akt-mTOR pathway mediates renal pericyte-myofibroblast transition by enhancing glycolysis through HKII

open access: yesJournal of Translational Medicine, 2023
Background Pericyte-myofibroblast transition (PMT) has been confirmed to contribute to renal fibrosis in several kidney diseases, and transforming growth factor-β1 (TGF-β1) is a well-known cytokine that drives PMT.
Liangmei Chen   +13 more
doaj   +1 more source

Insulin-Like Growth Factor Binding Proteins in Kidney Disease

open access: yesFrontiers in Pharmacology, 2021
The seven members of the insulin-like growth factor (IGF) binding protein family (IGFBPs) were initially considered to be the regulatory proteins of IGFs in the blood circulation, mainly as the subsequent reserve for bidirectional regulation of IGF ...
Shuqiang Wang   +4 more
doaj   +1 more source

On kidney disease [PDF]

open access: yesTransactions of the Royal Academy of Medicine in Ireland, 1917
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openaire   +2 more sources

Macrophage polarization in innate immune responses contributing to pathogenesis of chronic kidney disease

open access: yesBMC Nephrology, 2020
Chronic kidney disease (CKD) is characterized by inflammation, injury and fibrosis. Dysregulated innate immune responses mediated by macrophages play critical roles in progressive renal injury. The differentiation and polarization of macrophages into pro-
Hewang Lee   +4 more
doaj   +1 more source

Chronic kidney disease [PDF]

open access: yesThe Lancet, 2021
Chronic kidney disease is a progressive disease with no cure and high morbidity and mortality that occurs commonly in the general adult population, especially in people with diabetes and hypertension. Preservation of kidney function can improve outcomes and can be achieved through non-pharmacological strategies (eg, dietary and lifestyle adjustments ...
Kalantar-Zadeh, Kamyar   +4 more
openaire   +4 more sources

Better pulmonary function is associated with greater handgrip strength in a healthy Chinese Han population

open access: yesBMC Pulmonary Medicine, 2020
Background Handgrip strength (HGS) has been widely studied in clinical and epidemiological settings, but the relationship between HGS and pulmonary function is still controversial.
Liangmei Chen   +17 more
doaj   +1 more source

Porphyria and kidney diseases [PDF]

open access: yesClinical Kidney Journal, 2018
The kidneys, after the bone marrow and liver, are third in terms of the amounts of haem synthesized daily. Haem is incorporated into haemoproteins that are critical to renal physiology. In turn, disturbances in haem metabolism interfere with renal physiology and are tightly interrelated with kidney diseases.
Eric Thervet   +7 more
openaire   +4 more sources

Severity of Acute Kidney Injury and its Effect on Outcome in Patients of Dengue Virus Infection

open access: yesPakistan Journal of Medical Research, 2021
Background: Dengue fever is a mosquito borne viral illness that has endangered a vast population of tropical and sub-tropical areas. Dengue has multi-system involvement including liver, hematological, respiratory and central nervous systems. Spectrum of
Muhammad Tanzeel Abbasi   +5 more
doaj   +2 more sources

Clinical features of acute kidney injury in patients with nephrotic syndrome and minimal change disease: a retrospective, cross-sectional study

open access: yesChinese Medical Journal, 2021
. Background:. Minimal change nephropathy (MCD) is a common pathological type of nephrotic syndrome and is often associated with acute kidney injury (AKI).
Shu-Peng Lin   +9 more
doaj   +1 more source

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