Results 11 to 20 of about 29,325 (273)

Effects of palonosetron and ondansetron on preventing nausea and vomiting after laparoscopic surgery

Journal of International Medical Research, 2018
Background This meta-analysis was performed to evaluate the efficacy and safety of palonosetron and ondansetron in preventing postoperative nausea and vomiting (PONV) in patients undergoing laparoscopic surgery with general anesthesia.
Qili Liu, Chengmao Zhou, Zeqing Bao, Yu Zhu   +3 more
doaj   +2 more sources

Randomised, placebo‐controlled trial and meta‐analysis show benefit of ondansetron for irritable bowel syndrome with diarrhoea: The TRITON trial

Alimentary Pharmacology and Therapeutics, 2023
Ondansetron may be beneficial in irritable bowel syndrome with diarrhoea (IBS‐D).
D. Gunn, Rabia Topan, Lorna Barnard, R. Fried, I. Holloway, Richard Brindle, M. Corsetti, M. Scott, A. Farmer, K. Kapur, David S Sanders, M. Eugenicos, Nigel Trudgill, P. Whorwell, J. Mclaughlin, A. Akbar, L. Houghton, P. Dinning, Qasim Aziz, A. Ford, A. Farrin, R. Spiller   +21 more
semanticscholar   +1 more source

Development of a Generic Physiologically‐Based Pharmacokinetic Model for Lactation and Prediction of Maternal and Infant Exposure to Ondansetron via Breast Milk

Clinical pharmacology and therapy, 2022
Ondansetron is commonly used in breastfeeding mothers to treat nausea and vomiting. There is limited information in humans regarding safety of ondansetron exposure to nursing infants and no adequate study looking at ondansetron pharmacokinetics during ...
Kathleen M. Job, A. Dallmann, S. Parry, G. Saade, D. Haas, B. Hughes, P. Berens, Jia-Yu Chen, Christina Fu, Kelsey Humphrey, Christoph P. Hornik, Stephen Balevic, K. Zimmerman, K. Watt   +13 more
semanticscholar   +1 more source

Comparison of Pregnancy Outcomes of Patients Treated With Ondansetron vs Alternative Antiemetic Medications in a Multinational, Population-Based Cohort

JAMA Network Open, 2021
Key Points Question What is the association between ondansetron exposure during pregnancy and the risk of adverse fetal outcomes? Findings In this meta-analysis of cohort studies of 456 963 pregnancies in 3 countries, treatment with ondansetron was not ...
C. Dormuth, B. Winquist, Anat Fisher, Fangyun Wu, P. Reynier, S. Suissa, Matthew Dahl, Zhihai Ma, Xinya Lu, Jianguo Zhang, C. Raymond, K. Filion, R. Platt, C. Moriello, J. Paterson   +14 more
semanticscholar   +1 more source

Mapping Interictal activity in epilepsy using a hidden Markov model: A magnetoencephalography study

Human Brain Mapping, Volume 44, Issue 1, Page 66-81, January 2023., 2023
In this study, we use hidden Markov modeling (HMM) to create a unique statistical model of interictal brain activity for 10 pediatric epilepsy patients. This data‐driven model produces an output unique to each patient, and is used to localize the epileptogenic area(s).
Zelekha A. Seedat, Lukas Rier, Lauren E. Gascoyne, Harry Cook, Mark W. Woolrich, Andrew J. Quinn, Timothy P. L. Roberts, Paul L. Furlong, Caren Armstrong, Kelly St. Pier, Karen J. Mullinger, Eric D. Marsh, Matthew J. Brookes, William Gaetz   +13 more
wiley   +1 more source

Selective Laser Sintering 3D Printing of Orally Disintegrating Printlets Containing Ondansetron

Pharmaceutics, 2020
The aim of this work was to explore the feasibility of using selective laser sintering (SLS) 3D printing (3DP) to fabricate orodispersable printlets (ODPs) containing ondansetron.
Nour Allahham, Fabrizio Fina, Carmen Marcuta, Lilia Kraschew, W. Mohr, S. Gaisford, A. Basit, A. Goyanes   +7 more
semanticscholar   +1 more source

Early Postoperative Ondansetron Exposure is Associated with Reduced 90-Day Mortality in Patients Undergoing Cardiac Surgery

Frontiers in Surgery, 2022
BackgroundOndansetron is a widely used anti-emetic for the prevention and treatment of nausea and vomiting for patients in critical care. Recent retrospective cohort studies suggest the potential beneficial effects of ondansetron in critically ill ...
Dexin Xiong, Chao Xiong
doaj   +1 more source

Oral ondansetron administration in emergency departments to children with gastroenteritis: an economic analysis. [PDF]

PLoS Medicine, 2010
BACKGROUND: The use of antiemetics for children with vomiting is one of the most controversial decisions in the treatment of gastroenteritis in developed countries. Ondansetron, a selective serotonin receptor antagonist, has been found to be effective in
Stephen B Freedman, Michael J Steiner, Kevin J Chan   +2 more
doaj   +1 more source

The effect of ondansetron administration 20 minutes prior to spinal anaesthesia on haemodynamic status in patients undergoing elective caesarean section: A comparison between two different doses

Indian Journal of Anaesthesia, 2020
Background and Aims: Spinal anaesthesia is currently the most common method used for managing patients undergoing elective caesarean sections. Recent meta-analyses have been supporting the use of 5-HT3 antagonists, like ondansetron, to attenuate ...
Walid Samarah, Subhi M. Alghanem, Isam K. Bsisu, Z. Rahman, Hasan Guzu, Basil N Abufares   +5 more
semanticscholar   +1 more source

Effect of Fluoxetine and Paroxetine on Intestinal Motility in Presence of Ondansetron in ex-vivo Model

Life and Science, 2020
Objective: To understand the effects of fluoxetine and paroxetine with ondansetron on the intestinal motility of rabbit ileum. Study Design: Observational study.
Ayesha Afzal, Ammara Khan, Khalida Ajmal, Abeera Sikandar, Saima Rafiqu, Rashida Farooqi, Bushra Tayyaba Khan, Iffat Ara   +7 more
doaj   +1 more source