Results 11 to 20 of about 140,654 (50)

Harnessing PTEN’s Growth Potential in Neuronal Development and Disease

Neuroscience Insights, 2020
PTEN is a powerful regulator of neuronal growth. It globally suppresses axon extension and branching during both nervous system development and regeneration, by antagonizing growth-promoting PI3K/PI(3,4,5)P 3 signaling.
Joachim Fuchs, Britta J. Eickholt, George Leondaritis   +2 more
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Does Sex/Gender Play a Role in Placebo and Nocebo Effects? Conflicting Evidence From Clinical Trials and Experimental Studies

Frontiers in Neuroscience, 2019
Sex has been speculated to be a predictor of the placebo and nocebo effect for many years, but whether this holds true or not has rarely been investigated.
Paul Enck, Sibylle Klosterhalfen
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Perinatal exposure to glufosinate ammonium herbicide impairs neurogenesis and neuroblast migration through cytoskeleton destabilization

Frontiers in Cellular Neuroscience, 2016
Neurogenesis, a process of generating functional neurons from neural precursors, occurs throughout life in restricted brain regions such as the subventricular zone (SVZ).
Ameziane Herzine, Anthony Laugeray, Justyne Feat, Arnaud Menuet, Valérie Quesniaux, Olivier Richard, Jacques Pichon, Céline Montecot-Dubourg, Olivier Perche, Olivier Perche, Stéphane Mortaud   +10 more
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The Impact of Hippocampal Sex Hormones Receptors in Modulation of Depressive-Like Behavior Following Chronic Anabolic Androgenic Steroids and Exercise Protocols in Rats

Frontiers in Behavioral Neuroscience, 2019
The aim of this study was to evaluate alterations in depressive-like behaviors in rats following chronic administration of a supraphysiological dose of anabolic androgenic steroids (AASs) as well as exposure to a prolonged exercise protocol.
Dragica Selakovic, Jovana Joksimovic, Nemanja Jovicic, Slobodanka Mitrovic, Vladimir Mihailovic, Jelena Katanic, Dragan Milovanovic, Suzana Pantovic, Natasa Mijailovic, Gvozden Rosic   +9 more
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Neuroanatomy and function of human sexual behavior: A neglected or unknown issue?

Brain and Behavior, 2019
Introduction Sexual desire, arousal, and orgasm are mediated by complex, yet still not fully understood, interactions of the somatic and autonomic nervous systems operating at the central and peripheral levels.
Rocco S. Calabrò, Alberto Cacciola, Daniele Bruschetta, Demetrio Milardi, Fabrizio Quattrini, Francesca Sciarrone, Gianluca laRosa, Placido Bramanti, Giuseppe Anastasi   +8 more
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Alpha-synuclein mutations impair axonal regeneration in models of Parkinson´s disease

Frontiers in Aging Neuroscience, 2014
The dopaminergic (DAergic) nigrostriatal tract has an intrinsic regenerative capacity which can be impaired in Parkinson’s disease (PD). Alpha-synuclein (aSyn) is a major pathogenic component in PD but its impact on DAergic axonal regeneration is largely
Lars eTönges, Lars eTönges, Eva eSzegö, Patrizia eHause, Kim Ann Saal, Lars eTatenhorst, Jan Christoph Koch, Zara ed`Hedouville, Sebastian eKügler, Sebastian eKügler, Christoph eDohm, Christoph eDohm, Mathias eBähr, Mathias eBähr, Paul eLingor, Paul eLingor   +15 more
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Therapeutic Potential of a Prolyl Hydroxylase Inhibitor FG-4592 for Parkinson’s Diseases in Vitro and in Vivo: Regulation of Redox Biology and Mitochondrial Function

Frontiers in Aging Neuroscience, 2018
As the main transcription factor that regulates the cellular responses to hypoxia, Hypoxia-inducible factor-1α (HIF-1α) plays an important role in the pathogenesis of Parkinson’s disease (PD).
Xuan Li, Xin-Xin Cui, Ya-Jing Chen, Ting-Ting Wu, Huaxi Xu, Huiyong Yin, Huiyong Yin, Huiyong Yin, Yun-Cheng Wu   +8 more
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Application of Ferulic Acid for Alzheimer’s Disease: Combination of Text Mining and Experimental Validation

Frontiers in Neuroinformatics, 2018
Alzheimer’s disease (AD) is an increasing concern in human health. Despite significant research, highly effective drugs to treat AD are lacking. The present study describes the text mining process to identify drug candidates from a traditional Chinese ...
Guilin Meng, Guilin Meng, Xiulin Meng, Xiaoye Ma, Gengping Zhang, Xiaolin Hu, Aiping Jin, Yanxin Zhao, Xueyuan Liu   +8 more
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MicroRNAs in Hearing Disorders: Their Regulation by Oxidative Stress, Inflammation and Antioxidants

Frontiers in Cellular Neuroscience, 2017
MicroRNAs (miRs) are small non-coding single-stranded RNAs that bind to their complimentary sequences in the 3′-untranslated regions (3′-UTRs) of the target mRNAs that prevent their translation into the corresponding proteins.
Kedar N. Prasad, Stephen C. Bondy
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The Aerobic and Cognitive Exercise Study (ACES) for Community-Dwelling Older Adults With or At-Risk for Mild Cognitive Impairment (MCI): Neuropsychological, Neurobiological and Neuroimaging Outcomes of a Randomized Clinical Trial

Frontiers in Aging Neuroscience, 2018
Prior research has found that cognitive benefits of physical exercise and brain health in older adults may be enhanced when mental exercise is interactive simultaneously, as in exergaming.
Cay Anderson-Hanley, Nicole M. Barcelos, Earl A. Zimmerman, Robert W. Gillen, Mina Dunnam, Brian D. Cohen, Vadim Yerokhin, Kenneth E. Miller, David J. Hayes, Paul J. Arciero, Molly Maloney, Arthur F. Kramer   +11 more
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