Results 11 to 20 of about 13,789 (243)

Efficacy and safety outcomes for acute ischemic stroke patients treated with intravenous infusion of tirofiban after emergent carotid artery stenting [PDF]

Clinical Neuroradiology, 2023
Introduction Emergent stenting of the extracranial internal carotid artery (ICA) in stroke patients requires antiplatelet therapy to prevent in-stent thrombosis with a higher risk of intracranial haemorrhage.
Berlis, Ansgar, Ertl, Michael, Garayzade, Rana, Maurer, Christoph J., Müller, Gernot, Schiele, Stefan, Schneider, Hauke   +6 more
core   +2 more sources

Association of tirofiban treatment with outcomes following endovascular therapy in cardioembolic stroke: insights from the RESCUE BT randomized trial

European Journal of Medical Research, 2023
Background and purpose The efficacy and safety of tirofiban in endovascular therapy for cardioembolic ischemic stroke patients remain controversial.
Benbing Rong, Zhangbao Guo, Lijie Gao, Yuan Yang, Wenjie Zi, Zhongming Qiu, Fengli Li, Zhiyu Lv, Ying luo, Renliang Meng, Yang Xie, Ting Long, Shujiang Zhang, Jinshan Jiang, Jinfeng Tian, Jingling Zhao, Hongliang Zeng, Zhengzhou Yuan   +17 more
doaj   +2 more sources

Influence of tirofiban on stroke outcome after mechanical thrombectomy in acute vertebrobasilar artery occlusion

BMC Neurology, 2022
Background Even undergoing mechanical thrombectomy (MT), patients with acute vertebrobasilar artery occlusion (AVBAO) still have a high rate of mortality.
Xiding Pan, Mengyi Xu, Yuxiang Fei, Shiteng Lin, Yapeng Lin, Jianjun Zou, Jie Yang   +6 more
doaj   +2 more sources

Safety and efficacy of low-dose and long-course tirofiban in large hemispheric infarction

Frontiers in Neurology, 2022
BackgroundThe clinical efficacy and safety of tirofiban in the treatment of large hemispheric infarction (LHI) remain controversial.MethodsThis study prospectively enrolled patients with acute LHI who were admitted to Putuo Hospital affiliated with ...
Yinqin Hu, Qian Xiao, Zhizhen Shi, Yangbo Hou, Zhen Chen, Jiwei Cheng, Guoyi Li   +6 more
doaj   +2 more sources

Cost-effectiveness of tirofiban for acute ischemic stroke without large or medium-sized vessel occlusion: A Markov modelling analysis from the Chinese and United States perspectives.

PLoS ONE
BackgroundThe RESCUE BT2 trial recently showcased the efficacy of tirofiban in treating acute ischemic stroke (AIS) without large or medium-sized vessel occlusion.
Li Wang, Yuhong Zeng, Limei Zhou, Ping Xu, Xianbin Guo, Yu Xie, Junxiu Cai, Min Pan, Jie Tang, Qingtao Gong, Rong Su, Yan Liu, Yake Lou   +12 more
doaj   +2 more sources

Subtyping treatment response of tirofiban in acute ischemic stroke based on neuroimaging features

Clinical and Translational Science, 2023
In a previously published clinical trial, we demonstrated that tirofiban was effective and safe in acute ischemic stroke (AIS) patients who did not undergo early recanalization treatments.
Bin Han, Xu Man, Jian Ding, Yuzhu Li, Xintao Tian, Xuelian Zhu, Jiang Yu, Jinping Sun   +7 more
doaj   +2 more sources

Tirofiban combined with Aspirin in the Treatment of Acute Penetrating Artery Territory Infarction (STRATEGY): protocol for a multicentre, randomised controlled trial

Stroke and Vascular Neurology, 2023
Background Perforating artery territorial infarction (PAI) caused by branch atheromatous disease (BAD) is prone to recurrence and early progression without an effective and well-documented antiplatelet treatment regimen.
Liping Liu, Yongjun Wang, Yilong Wang, Xingquan Zhao, Xiaoling Liao, Weiqi Chen, Yuesong Pan, Hui Qu, Shuo Feng, Yicong Wang   +9 more
doaj   +2 more sources

Safety and Efficacy of Tirofiban During Intravenous Thrombolysis Bridging to Mechanical Thrombectomy for Acute Ischemic Stroke Patients: A Meta-Analysis

Frontiers in Neurology, 2022
IntroductionThe safety and efficacy of tirofiban in intravenous thrombolysis (IVT) bridging to mechanical thrombectomy in patients with acute ischemic stroke (AIS) is unknown.
Wei Li, Wei Li, Wei Li, Guohui Lin, Zaixing Xiao, Zaixing Xiao, Yichuan Zhang, Yichuan Zhang, Bin Li, Bin Li, Yu Zhou, Yu Zhou, Erqing Chai, Erqing Chai   +13 more
doaj   +2 more sources

Case report: reuse of tirofiban leads to very severe thrombocytopenia

Frontiers in Cardiovascular Medicine, 2023
BackgroundTelofiban is a class of small molecule non-peptide tyrosine derivatives containing RGD sequences. It is the only platelet surface glycoprotein (GP) IIb/IIIa receptor antagonist (GPI) currently marketed in China.
Yuqing Li, Jiuchun Qiu, Yi Gao, Guangping Li   +3 more
doaj   +2 more sources

The safety and efficacy of intra-arterial low-dose tirofiban administration during endovascular therapy in patients with large ischemic core volume

Scientific Reports
This study aimed to evaluate the safety and efficacy of intra-arterial (IA) administration of low- dose tirofiban during endovascular therapy in patients with large ischemic core volumes on initial brain CT. Patients were divided into two groups based on
Kwang-Chun Cho, Nak-Hoon Son, So Hyeon Gwon, Jin Wook Choi, Woo Sang Jung   +4 more
doaj   +2 more sources