Results 21 to 30 of about 56,255 (180)

Stenting versus endarterectomy for treatment of carotid-artery stenosis.

New England Journal of Medicine, 2010
BACKGROUND Carotid-artery stenting and carotid endarterectomy are both options for treating carotid-artery stenosis, an important cause of stroke. METHODS We randomly assigned patients with symptomatic or asymptomatic carotid stenosis to undergo ...
T. Brott, R. Hobson, G. Howard
semanticscholar   +1 more source

Protected carotid-artery stenting versus endarterectomy in high-risk patients.

New England Journal of Medicine, 2004
BACKGROUND Carotid endarterectomy is more effective than medical management in the prevention of stroke in patients with severe symptomatic or asymptomatic atherosclerotic carotid-artery stenosis. Stenting with the use of an emboli-protection device is a
J. Yadav, M. Wholey, R. Kuntz, P. Fayad, B. Katzen, G. Mishkel, T. Bajwa, P. Whitlow, N. Strickman, M. Jaff, J. Popma, David B Snead, D. Cutlip, B. Firth, K. Ouriel   +14 more
semanticscholar   +1 more source

Endarterectomy for asymptomatic carotid artery stenosis

British medical journal, 1995
Reasonable doubt justifies randomisation European and North American clinicians have always differed in their management of carotid artery disease.1 Carotid endarterectomy is one of the commonest vascular procedures in North America, with over 360 ...
C. Irvine, R. Baird, P. Lamont, A. Davies   +3 more
semanticscholar   +1 more source

Pulmonary endarterectomy in the management of chronic thromboembolic pulmonary hypertension

European Respiratory Review, 2017
Chronic thromboembolic pulmonary hypertension (CTEPH) is a type of pulmonary hypertension, resulting from fibrotic transformation of pulmonary artery clots causing chronic obstruction in macroscopic pulmonary arteries and associated vascular remodelling ...
D. Jenkins, M. Madani, E. Fadel, A. D'Armini, E. Mayer   +4 more
semanticscholar   +1 more source

Long-Term Results of Stenting versus Endarterectomy for Carotid-Artery Stenosis.

New England Journal of Medicine, 2016
BACKGROUND In the Carotid Revascularization Endarterectomy versus Stenting Trial, we found no significant difference between the stenting group and the endarterectomy group with respect to the primary composite end point of stroke, myocardial infarction,
T. Brott, G. Howard, G. Roubin, J. Meschia, A. Mackey, W. Brooks, W. Moore, M. Hill, V. Mantese, W. Clark, C. Timaran, D. Heck, P. Leimgruber, A. Sheffet, V. Howard, S. Chaturvedi, B. Lal, Jenifer H. Voeks, R. Hobson   +18 more
semanticscholar   +1 more source

Dynamic Risk Stratification of Patient Long-Term Outcome After Pulmonary Endarterectomy: Results From the United Kingdom National Cohort

Circulation, 2016
Background— Chronic thromboembolic pulmonary hypertension results from incomplete resolution of pulmonary emboli. Pulmonary endarterectomy (PEA) is potentially curative, but residual pulmonary hypertension following surgery is common and its impact on ...
J. Cannon, L. Su, D. Kiely, K. Page, M. Toshner, E. Swietlik, C. Treacy, A. Ponnaberanam, R. Condliffe, K. Sheares, D. Taboada, J. Dunning, S. Tsui, C. Ng, D. Gopalan, N. Screaton, C. Elliot, S. Gibbs, L. Howard, P. Corris, J. Lordan, Martin Johnson, A. Peacock, R. Mackenzie-Ross, B. Schreiber, G. Coghlan, K. Dimopoulos, S. Wort, S. Gaine, S. Moledina, D. Jenkins, J. Pepke-Zaba   +31 more
semanticscholar   +1 more source

Changes in retinal flow density measured by optical coherence tomography angiography in patients with carotid artery stenosis after carotid endarterectomy

Scientific Reports, 2018
The aim of the study presented here was to evaluate retinal and optic nerve head (ONH) perfusion in patients with severe asymptomatic carotid artery stenosis (CAS) compared with healthy controls and to analyze the impact of carotid endarterectomy using ...
L. Lahme, E. Marchiori, Giuseppe Panuccio, P. Nelis, Friederike Schubert, N. Mihailovic, G. Torsello, N. Eter, M. Alnawaiseh   +8 more
semanticscholar   +1 more source

Carotid Endarterectomy and Carotid Artery Stenting in the US Medicare Population, 1999-2014

Journal of the American Medical Association (JAMA), 2017
Importance Carotid endarterectomy and carotid artery stenting are the leading approaches to revascularization for carotid stenosis, yet contemporary data on trends in rates and outcomes are limited. Objective To describe US national trends in performance
J. Lichtman, Michael R. Jones, Erica C. Leifheit, A. Sheffet, G. Howard, B. Lal, V. Howard, Yun Wang, J. Curtis, T. Brott   +9 more
semanticscholar   +1 more source

Macrophage HM13/SPP Enhances Foamy Macrophage Formation and Atherogenesis

Advanced Science, EarlyView.
Previous research suggests that AIP may prevent atherogenic foamy macrophage formation. This study reveals that AIP, via its chaperone interaction with AHR, inhibits p38‐c‐JUN‐mediated transactivation of HM13, which encodes the ERAD protease HM13/SPP. HM13/SPP promotes foamy macrophage formation in addition to atherogenesis and plaque foamy macrophage ...
Yu Cao, Qirong Xie, Qiang Zheng, Jingping Zhang, Mengyu Yao, Zhongyong Du, Lujun Zhang, Tianyang Hu, Yunli Zhao, Jianlin Du, Yongyong Li, Yuxing Feng, ND Melgiri, Xiaodong Zhao, Rongzhong Huang, Yang Sun   +15 more
wiley   +1 more source

Carotid endarterectomy for symptomatic carotid stenosis.

Cochrane Database of Systematic Reviews, 2017
BACKGROUND Severe narrowing (stenosis) of the carotid artery is an important cause of stroke. Surgical treatment (carotid endarterectomy) may reduce the risk of stroke, but carries a risk of operative complications.
K. Rerkasem, P. Rothwell
semanticscholar   +1 more source