Results 21 to 30 of about 857,514 (313)

Polycystic kidney disease [PDF]

Nature Reviews Disease Primers, 2018
Cystic kidneys are common causes of end-stage renal disease, both in children and in adults. Autosomal dominant polycystic kidney disease (ADPKD) and autosomal recessive polycystic kidney disease (ARPKD) are cilia-related disorders and the two main forms of monogenic cystic kidney diseases.
Bergmann, C., Guay-Woodford, L.M., Harris, P.C., Horie, S., Peters, D.J.M., Torres, V.E.   +5 more
openaire   +5 more sources

Regulation of connective tissue growth factor expression by miR-133b for the treatment of renal interstitial fibrosis in aged mice with unilateral ureteral obstruction

Stem Cell Research & Therapy, 2021
Introduction Renal interstitial fibrosis, an important pathological feature of kidney aging and chronic renal failure, is regulated by mesenchymal stem cells (MSCs).
Dan Cao, Yuan Wang, Yingjie Zhang, Yinping Zhang, Qi Huang, Zhong Yin, Guangyan Cai, Xiangmei Chen, Xuefeng Sun   +8 more
doaj   +1 more source

Chronic kidney disease [PDF]

Nature Reviews Disease Primers, 2017
Chronic kidney disease (CKD) is defined by persistent urine abnormalities, structural abnormalities or impaired excretory renal function suggestive of a loss of functional nephrons. The majority of patients with CKD are at risk of accelerated cardiovascular disease and death.
Romagnani, Paola, Remuzzi, Giuseppe, Glassock, Richard, Levin, Adeera, Jager, Kitty J., Tonelli, Marcello, Massy, Ziad, Wanner, Christoph, Anders, Hans-Joachim   +8 more
openaire   +2 more sources

Evaluation of factors related to depression in peritoneal dialysis patients: a multicenter cross-sectional study

Renal Replacement Therapy, 2023
Background End-stage renal disease (ESRD) is serious global public health challenge in many developing countries. Treatment of ESRD is carried out through renal replacement therapy like peritoneal dialysis (PD).
Sepehr Bazazzadeh, Mohammad Reza Sharbafchi, Maryam Kazemi Naeini, Sayed Mohsen Hosseini, Abdolamir Atapour, Mojgan Mortazavi   +5 more
doaj   +1 more source

Efficacy and Safety of Daprodustat Vs rhEPO for Anemia in Patients With Chronic Kidney Disease: A Meta-Analysis and Trial Sequential Analysis

Frontiers in Pharmacology, 2022
Introduction: Daprodustat, a novel hypoxia-inducible factor prolyl-hydroxylase inhibitor (HIF-PHI), its efficacy and safety remain unclear. Thus, we conducted this meta-analysis aiming at investigating its efficacy and safety on the treatment of patients
Zhangning Fu, Zhangning Fu, Xiaodong Geng, Xiaodong Geng, Kun Chi, Kun Chi, Chengcheng Song, Chengcheng Song, Di Wu, Chao Liu, Chao Liu, Quan Hong, Quan Hong   +12 more
doaj   +1 more source

Kidney disease in Paraguay [PDF]

Kidney International, 2005
Paraguay is a landlocked country located in South America with a total population of 5,884,491. Most of the population (95%) is mestizo, a mixture of Spanish and American/Indian races. The total number of indigenous people in the country has increased from 38,703 in 1981 to 85,674 in 2002.
Francisco Vicente Santa Cruz, Susana Barreto, Maria Magdalena Mayor, Walter E. Cabrera, Diana Baez   +4 more
openaire   +3 more sources

Validity and applicability of the global leadership initiative on malnutrition criteria in non-dialysis patients with chronic kidney disease

Frontiers in Nutrition
IntroductionThere are no standardized assessment criteria for selecting nutritional risk screening tools or indicators to assess reduced muscle mass (RMM) in the Global Leadership Initiative on Malnutrition (GLIM) criteria.
Hui Huang, Hui Huang, Qian Wang, Yayong Luo, Yayong Luo, Zhengchun Tang, Zhengchun Tang, Fang Liu, Fang Liu, Ruimin Zhang, Ruimin Zhang, Guangyan Cai, Jing Huang, Li Zhang, Li Zeng, Xueying Cao, Jian Yang, Yong Wang, Keyun Wang, Yaqing Li, Qihu Li, Qihu Li, Xiangmei Chen, Xiangmei Chen, Zheyi Dong   +24 more
doaj   +1 more source

Association between sarcopenia and frailty in elderly patients with chronic kidney disease

Journal of Cachexia, Sarcopenia and Muscle, 2023
Background Frailty and sarcopenia are prevalent in chronic kidney disease (CKD) populations and could increase the risk for adverse health outcomes.
Che Wang, Xinru Guo, Xieguanxuan Xu, Shuang Liang, Wenling Wang, Fanglei Zhu, Siyang Wang, Jie Wu, Li Zhang, Xuefeng Sun, Xiangmei Chen, Guangyan Cai, The Chinese observational prospective study of ageing population with chronic kidney disease (C‐OPTION)   +12 more
doaj   +1 more source

Ferroptosis and kidney disease

Nefrología (English Edition), 2020
Cell death is a finely regulated process occurring through different pathways. Regulated cell death, either through apoptosis or regulated necrosis offers the possibility of therapeutic intervention. Necroptosis and ferroptosis are among the best studied forms of regulated necrosis in the context of kidney disease.
Alberto Ortiz, Julio M. Martinez-Moreno, Miguel Fontecha-Barriuso, Ana Belen Sanz, Diego Martin-Sanchez, Melania Guerrero-Hue, Maria Dolores Sanchez-Niño, Juan Antonio Moreno, Adrian M. Ramos   +8 more
openaire   +4 more sources

Myeloperoxidase in kidney disease [PDF]

Kidney International, 2003
In glomerular and tubulointerstitial disease, polymorphonuclear- and monocyte-derived reactive oxygen species may contribute to oxidative modification of proteins, lipids, and nucleic acids. In part, the processes instigated by reactive oxygen species parallel events that lead to the development of atherosclerosis. Myeloperoxidase (MPO), a heme protein
Ernst Malle, Thomas Buch, Thomas Buch, Hermann Josef Grone, Hermann Josef Grone   +4 more
openaire   +2 more sources