Results 21 to 30 of about 2,137,213 (424)

miR-625-5p promotes proliferation and invasion of lung adenocarcinoma by targeting PRKACA [PDF]

Zhongguo aizheng zazhi, 2021
Background and purpose: Lung adenocarcinoma is a subtype of non-small cell lung cancer. Although much progress has been made in the diagnosis and treatment of lung adenocarcinoma, the clinical prognosis and overall survival of advanced lung  ...
HU Yaqiong , BAI Jun , CHEN Lin , CHEN Xinlu , ZHANG Liping , ZHOU Dandan , WANG Yu , YIN Chonggao , LI Hongli , LIU Yuqing
doaj   +1 more source

Single-cell RNA sequencing demonstrates the molecular and cellular reprogramming of metastatic lung adenocarcinoma

Nature Communications, 2020
Advanced metastatic cancer poses utmost clinical challenges and may present molecular and cellular features distinct from an early-stage cancer. Herein, we present single-cell transcriptome profiling of metastatic lung adenocarcinoma, the most prevalent ...
N. Kim, H. Kim, K. Lee, Yourae Hong, J. Cho, J. Choi, Jung-Il Lee, Y. Suh, B. Ku, Hye Hyeon Eum, Soyean Choi, Yoon-La Choi, Je-Gun Joung, W. Park, H. Jung, Jong-Mu Sun, Se-Hoon Lee, J. Ahn, Keunchil Park, M. Ahn, Hae-Ock Lee   +20 more
semanticscholar   +1 more source

Decoding the multicellular ecosystem of lung adenocarcinoma manifested as pulmonary subsolid nodules by single-cell RNA sequencing

Science Advances, 2021
Lung adenocarcinoma manifesting as radiological subsolid nodules has distinct cell composition within its tumor microenvironment. Lung adenocarcinomas (LUAD) that radiologically display as subsolid nodules (SSNs) exhibit more indolent biological behavior
Xudong Xing, Fan Yang, Qi Huang, Haifa Guo, Jiawei Li, M. Qiu, F. Bai, Jun Wang   +7 more
semanticscholar   +1 more source

Follistatin is a novel biomarker for lung adenocarcinoma in humans. [PDF]

PLoS ONE, 2014
Follistatin (FST), a single chain glycoprotein, is originally isolated from follicular fluid of ovary. Previous studies have revealed that serum FST served as a biomarker for pregnancy and ovarian mucinous tumor.
Fangfang Chen, Ping Ren, Ye Feng, Haiyan Liu, Yang Sun, Zhonghui Liu, Jingyan Ge, Xueling Cui   +7 more
doaj   +1 more source

Hepatoid adenocarcinoma of the lung [PDF]

QJM, 2016
Learning Point for Clinicians Hepatoid adenocarcinoma of lung is a rare type of lung cancer which is defined as an α-fetoprotein—producing primary carcinoma with morphological features similar to hepatocellular carcinoma. Establishing the diagnosis of HAL is worthwhile because of the potential for altered management. A 79-year-old Chinese male smoker
F.-Y. Yin, J.-G. Chu, Guo-Xiang Li, Guoqing Qian   +3 more
openaire   +3 more sources

Expression of LDL receptor-related proteins (LRPs) in common solid malignancies correlates with patient survival [PDF]

, 2017
LDL receptor-related proteins (LRPs) are transmembrane receptors involved in endocytosis, cell-signaling, and trafficking of other cellular proteins. Considerable work has focused on LRPs in the fields of vascular biology and neurobiology.
Gilder, Andrew S., Gonias, Steven L., Karimi-Mostowfi, Nicki, Mantuano, Elisabetta, Murray, Sarah S.   +4 more
core   +12 more sources

Deciphering cell lineage specification of human lung adenocarcinoma with single-cell RNA sequencing

Nature Communications, 2021
Lung adenocarcinomas (LUAD) arise from precancerous lesions such as atypical adenomatous hyperplasia, which progress into adenocarcinoma in situ and minimally invasive adenocarcinoma, then finally into invasive adenocarcinoma.
Zhoufeng Wang, Zhe Li, K. Zhou, Chengdi Wang, Lili Jiang, Li Zhang, Ying Yang, Wenxin Luo, Wenlian Qiao, Gang Wang, Yinyun Ni, S. Dai, Tingting Guo, G. Ji, Minjie Xu, Yiying Liu, Zhixi Su, G. Che, Wei-min Li   +18 more
semanticscholar   +1 more source

PD-L1 lncRNA splice isoform promotes lung adenocarcinoma progression via enhancing c-Myc activity

Genome Biology, 2021
Background Although using a blockade of programmed death-ligand 1 (PD-L1) to enhance T cell immune responses shows great promise in tumor immunotherapy, the immune-checkpoint inhibition strategy is limited for patients with solid tumors.
Shuang Qu, Zichen Jiao, Geng Lu, B. Yao, Ting Wang, Weiwei Rong, Jiahan Xu, T. Fan, Xinlei Sun, Rong-jiao Yang, Jun Wang, Yongzhong Yao, Guifang Xu, Xin Yan, Tao Wang, Hongwei Liang, Ke Zen   +16 more
semanticscholar   +1 more source

Massive malignant pleural effusion due to lung adenocarcinoma in 13-year-old boy [PDF]

, 2016
A 13-year-old boy with no risk factors for lung cancer presented with a massive left-sided pleural effusion and a mediastinal shift on chest radiography and computed tomography. A chest tube drained bloody pleural fluid with an exudative pattern.
Afghani, R., Azarhoush, R., Hajimohammadi, A., Kazemi-Nejad, V., Rezapour Esfahani, M., Yari, B.   +5 more
core   +1 more source

Innate Immune Landscape in Early Lung Adenocarcinoma by Paired Single-Cell Analyses

Cell, 2017
Andrew M Leader, Camille Bigenwald, Andrew Chow   +2 more
exaly   +2 more sources