Results 1 to 10 of about 1,201,752 (348)

Hmga2 is dispensable for pancreatic cancer development, metastasis, and therapy resistance. [PDF]

, 2018
Expression of the chromatin-associated protein HMGA2 correlates with progression, metastasis and therapy resistance in pancreatic ductal adenocarcinoma (PDAC). Hmga2 has also been identified as a marker of a transient subpopulation of PDAC cells that has
Chiou, Shin-Heng, Dorsch, Madeleine, Grüner, Barbara M, Koong, Albert C, Kozak, Margaret M, Kusch, Eva, Naranjo, Santiago, Winslow, Monte M   +7 more
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Tumor-associated microbiome features of metastatic colorectal cancer and clinical implications

Frontiers in Oncology
BackgroundColon microbiome composition contributes to the pathogenesis of colorectal cancer (CRC) and prognosis. We analyzed 16S rRNA sequencing data from tumor samples of patients with metastatic CRC and determined the clinical implications.Materials ...
Ho Jung An, Ho Jung An, Mira A. Partha, HoJoon Lee, Billy T. Lau, Dmitri S. Pavlichin, Alison Almeda, Anna C. Hooker, Giwon Shin, Hanlee P. Ji, Hanlee P. Ji   +10 more
doaj   +1 more source

Malignant Transformation in Tailgut Cyst Presenting as Retrorectal Adenosquamous Carcinoma: A Case Report [PDF]

Journal of Clinical and Diagnostic Research
Tailgut cysts are rare congenital retrorectal lesions that can rarely undergo malignant transformation. Occurring predominantly in middle-aged females, these lesions are mostly asymptomatic, with rare symptoms arising mostly in association with ...
Dipkana Das, Raya Banerjee, Durgaprasad Nanda, Namrata Maity   +3 more
doaj   +1 more source

Analysis of the Clinicopathologic Characteristics of Lung Adenocarcinoma With CTNNB1 Mutation

Frontiers in Genetics, 2020
IntroductionLung adenocarcinoma with CTNNB1 mutation is relatively uncommon, and its clinicopathologic characteristics, disease course, and prognosis have not been well-studied.MethodsA total of 564 lung adenocarcinoma patients were enrolled in this ...
Chao Zhou, Chao Zhou, Wentao Li, Jinchen Shao, Jikai Zhao, Chang Chen   +5 more
doaj   +1 more source

Surgical approaches to adenocarcinoma of the gastroesophageal junction: the Siewert II conundrum. [PDF]

, 2017
BACKGROUND: The Siewert classification system for gastroesophageal junction adenocarcinoma has provided morphological and topographical information to help guide surgical decision-making.
Berger, Adam C., Brown, Andrew M., Giugliano, Danica N., Palazzo, Francesco, Pucci, Michael J.   +4 more
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FGFR1 Cooperates with EGFR in Lung Cancer Oncogenesis, and Their Combined Inhibition Shows Improved Efficacy [PDF]

, 2019
Introduction: There is substantial evidence for the onco- genic effects of fi broblast growth factor receptor 1 (FGFR1) in many types of cancer, including lung cancer, but the role of this receptor has not been addressed speci fi cally in lung ...
Carnero Moya, Amancio, Cirauqui, Cristina, Conde, Esther, Enguita, Ana Belén, Ferrer, Irene, Marrugal, Ángela, Molina Pinelo, Sonia, Ojeda Márquez, Laura, Paz Ares, Luis, Ponce Aix, Santiago, Quintanal Villalonga, Álvaro Diego, Suárez, Rocío   +11 more
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EGFR Mutation Detection in Whole Slide Images of Non‐Small Cell Lung Cancers Using a Two‐Stage Deep Transfer Learning Approach

Cancer Medicine
Background Lung cancer (LC) is the leading cause of cancer death worldwide. Non‐small cell lung cancer is the most frequent and includes adenocarcinoma and squamous cell carcinoma. Currently, LC treatment is based on tumor molecular profiling.
Michele Zanoletti, Filippo Ugolini, Laila El Bachiri, Valeria Pasini, Marco Laurino, Francesco De Logu, Eleonora Melissa, Carolina Marchi, Maria Colombino, Daniela Massi, Guido Rindi, Camilla Eva Comin, Giuseppe Palmieri, Antonio Cossu   +13 more
doaj   +1 more source

Prognostic significance of tumor budding in endometrial cancer: clinicopathological insights [PDF]

Korean Journal of Clinical Oncology
Purpose Endometrial cancer is one of the most common gynecological cancers worldwide, with rising incidence rates. Despite therapeutic advances, it remains a significant cause of cancer-related deaths. Tumor budding (TB), characterized by single cells or
Ashi Dubey, Sana Ahuja, Sufian Zaheer
doaj   +1 more source

Colon adenocarcinoma diagnosis in human samples by multicontrast nonlinear optical microscopy of hematoxylin and eosin stained histological sections [PDF]

, 2014
Combined multimodal nonlinear optical (NLO) microscopies were used to detect and quantify morphological changes associated with stroma and epithelial transformation in colon cancer.
Adur, Javier Fernando, Bianchi, Mariana, Carvalho, Hernandes Faustino, Casco, Victor Hugo, Cesar, Carlos L., Izaguirre, María Fernanda, Pelegati, Vitor B., Viale, Silvia   +7 more
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Proteins associated with pancreatic cancer survival in patients with resectable pancreatic ductal adenocarcinoma. [PDF]

, 2015
Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal disease with a dismal prognosis. However, while most patients die within the first year of diagnosis, very rarely, a few patients can survive for >10 years.
Brentnall, Teresa A, Chen, Ru, Crispin, David A, Dawson, David W, de Wilde, Roeland F, Lai, Lisa A, Lay, Anna R, Maitra, Anirban, May, Damon H, McIntosh, Martin W, Ottenhof, Niki A, Pan, Sheng, Simeone, Diane M, Waghray, Meghna, Wang, Shouli, Wolfgang, Christopher L   +15 more
core   +1 more source