Results 11 to 20 of about 1,201,752 (348)
Nivolumab plus chemotherapy versus chemotherapy as first-line treatment for advanced gastric cancer/gastroesophageal junction cancer/oesophageal adenocarcinoma (CheckMate 649): a multicentre, randomised, open-label, phase 3 trial
The Lancet, 2021 Summary Background First-line chemotherapy for advanced/metastatic human epidermal growth factor receptor 2 (HER2)-negative gastric/gastroesophageal junction (GEJ) adenocarcinoma results in median overall survival (OS) Y. Janjigian, K. Shitara, M. Moehler, M. Garrido, P. Salman, L. Shen, L. Wyrwicz, K. Yamaguchi, T. Skoczylas, A. Bragagnoli, Tianshu Liu, M. Schenker, P. Yánez, M. Tehfé, R. Kowalyszyn, M. Karamouzis, R. Brugés, T. Zander, R. Pazo-Cid, E. Hitre, K. Feeney, J. Cleary, V. Poulart, D. Cullen, M. Lei, H. Xiao, K. Kondo, Mingshun Li, J. Ajani +28 moresemanticscholar +1 more sourceZolbetuximab plus CAPOX in CLDN18.2-positive gastric or gastroesophageal junction adenocarcinoma: the randomized, phase 3 GLOW trial
Nature Medicine, 2023 In the randomized, double-blind, phase 3 GLOW trial, capecitabine and oxaliplatin combined with zolbetuximab, a monoclonal antibody that targets CLDN18.2, significantly improved progression-free survival and overall survival in patients with CLDN18.2 ...M. Shah, K. Shitara, J. Ajani, Y. Bang, P. Enzinger, D. Ilson, F. Lordick, E. Van Cutsem, J. Gallego Plazas, Jing Huang, L. Shen, S. Oh, P. Sunpaweravong, Hwoei Fen Soo Hoo, H. Turk, Mok Oh, J. Park, Diarmuid Moran, Pranob P. Bhattacharya, A. Arozullah, Ruifeng Xu +20 moresemanticscholar +1 more sourceLung adenocarcinoma promotion by air pollutants
Nature, 2023 A complete understanding of how exposure to environmental substances promotes cancer formation is lacking. More than 70 years ago, tumorigenesis was proposed to occur in a two-step process: an initiating step that induces mutations in healthy cells ...William Hill, Emilia L. Lim, C. Weeden, Claudia Lee, M. Augustine, Kezhong Chen, F. Kuan, F. Marongiu, E. J. Evans, D. Moore, F. S. Rodrigues, O. Pich, B. Bakker, H. Cha, R. Myers, F. van Maldegem, J. Boumelha, S. Veeriah, A. Rowan, C. Naceur-Lombardelli, T. Karasaki, Monica Sivakumar, Swapnanil De, D. Caswell, Ai Nagano, James R. M. Black, Carlos Martínez-Ruiz, M. Ryu, Ryan D. Huff, Shijian Li, M. Favé, Alastair Magness, A. Suárez‐Bonnet, S. Priestnall, M. Lüchtenborg, K. Lavelle, Joanna Pethick, Steven I Hardy, F. McRonald, Meng-Hung Lin, Clara I. Troccoli, Moumita Ghosh, Y. Miller, D. Merrick, R. Keith, M. Al Bakir, Chris Bailey, M. Hill, L. Saal, Yilun Chen, A. George, C. Abbosh, N. Kanu, Se-Hoon Lee, N. Mcgranahan, C. Berg, P. Sasieni, R. Houlston, C. Turnbull, Stephen Lam, P. Awadalla, E. Grönroos, J. Downward, T. Jacks, C. Carlsten, I. Malanchi, A. Hackshaw, K. Litchfield, Jason F. Amrita Apostolos Azmina Keng Mohamad Mohammed F Lester Bajaj Nakas Sodha-Ramdeen Ang Tufail Chowdh, Jason Lester, A. Bajaj, A. Nakas, Azmina Sodha-Ramdeen, K. Ang, M. Tufail, M. F. Chowdhry, M. Scotland, R. Boyles, S. Rathinam, Claire Wilson, Domenic Marrone, S. Dulloo, D. Fennell, Gurdeep Matharu, J. Shaw, Joan Riley, L. Primrose, E. Boleti, Heather Cheyne, Mohammed Khalil, S. Richardson, Tracey Cruickshank, Gillian Price, K. Kerr, S. Benafif, Kayleigh Gilbert, B. Naidu, Akshay J. Patel, A. Osman, Christer Lacson, G. Langman, Helen Shackleford, M. Djearaman, S. Kadiri, Gary Middleton, Angela E. Leek, Jack Davies Hodgkinson, Nicola Totten, A. Montero, E. Smith, E. Fontaine, F. Granato, H. Doran, Juliette Novasio, K. Rammohan, L. Joseph, P. Bishop, R. Shah, Stuart Moss, Vijay Joshi, P. Crosbie, F. Gomes, Kate Brown, M. Carter, A. Chaturvedi, L. Priest, P. Oliveira, C. Lindsay, F. Blackhall, M. Krebs, Y. Summers, A. Clipson, J. Tugwood, Alastair Kerr, D. Rothwell, E. Kilgour, C. Dive, H. Aerts, R. Schwarz, Tom L. Kaufmann, G. Wilson, R. Rosenthal, P. van Loo, Nicolai J. Birkbak, Z. Szallasi, Judit Kisistók, M. Sokač, Roberto Salgado, M. Dióssy, J. Demeulemeester, Abigail Bunkum, A. Stewart, A. Frankell, A. Karamani, A. Toncheva, A. Huebner, B. Chain, B. Campbell, Carla Castignani, C. Puttick, Corentin Richard, C. Hiley, D. Pearce, D. Karagianni, D. Biswas, D. Levi, Elena Hoxha, E. L. Cadieux, E. Colliver, E. Nye, F. Gálvez-Cancino, Foteini Athanasopoulou, F. Gimeno-Valiente, G. Kassiotis, Georgia Stavrou, Gerasimos Mastrokalos, Haoran Zhai, H. Lowe, Ignacio Matos, J. Goldman, J. Reading, Javier Herrero, J. Rane, J. Nicod, J. Lam, J. Hartley, K. Peggs, Katey S. S. Enfield, Kayalvizhi Selvaraju, K. Thol, K. Ng, K. Dijkstra, Kristiana Grigoriadis, K. Thakkar, L. Ensell, Mansi Shah, Mar Durán, Maria Litovchenko, M. W. Sunderland, M. Dietzen, Michelle M. Leung, M. Escudero, Mihaela Angelova, M. Tanić, O. Chervova, O. Lucas, O. Al-Sawaf, Paulina Prymas, P. Hobson, Piotr Pawlik, R. Stone, R. Bentham, R. Hynds, R. Vendramin, S. Saghafinia, Saioa López, Samuel Gamble, S. Ung, S. Quezada, S. Vanloo, Simone Zaccaria, S. Hessey, S. Ward, S. Boeing, Stephan Beck, S. Bola, Tamara Denner, T. Marafioti, Thanos P. Mourikis, T. Watkins, V. Spanswick, Vittorio Barbè, Wei-Ting Lu, Wing-Kin Liu, Yin Wu, Yutaka Naito, Z. Ramsden, C. Veiga, G. Royle, C. Collins-Fekete, F. Fraioli, P. Ashford, T. Clark, Martin D. Forster, Siow-Ming Lee, E. Borg, M. Falzon, D. Papadatos-Pastos, James Wilson, T. Ahmad, A. Procter, Asia Ahmed, Magali N. Taylor, A. Nair, D. Lawrence, D. Patrini, N. Navani, R. Thakrar, S. Janes, E. M. Hoogenboom, Fleur Monk, James W. Holding, Junaid Choudhary, Kunal Bhakhri, M. Scarci, M. Hayward, N. Panagiotopoulos, Pat Gorman, R. Khiroya, R. Stephens, Y. Wong, S. Bandula, A. Sharp, Sean Smith, N. Gower, H. Dhanda, Kitty Chan, Camilla Pilotti, R. Leslie, Anca-Ioana Grapa, Hanyun Zhang, K. AbdulJabbar, Xiaoxi Pan, Yinyin Yuan, D. Chuter, M. Mackenzie, S. Chee, A. Alzetani, J. Cave, Lydia Scarlett, J. Richards, Papawadee Ingram, S. Austin, Eric Lim, P. De Sousa, S. Jordan, A. Rice, H. Raubenheimer, H. Bhayani, L. Ambrose, A. Devaraj, Hema Chavan, S. Begum, S. Buderi, Daniel Kaniu, Mpho Malima, S. Booth, A. Nicholson, Nádia Fernandes, P. Shah, C. Proli, M. Hewish, S. Danson, M. Shackcloth, Lily Robinson, P. Russell, K. Blyth, C. Dick, J. Le Quesne, A. Kirk, M. Asif, R. Bilancia, N. Kostoulas, Mathew Thomas, J. DeGregori, M. Jamal-Hanjani, C. Swanton +326 moresemanticscholar +1 more sourcePancreatic Adenocarcinoma, Version 2.2021, NCCN Clinical Practice Guidelines in Oncology.
The Journal of the National Comprehensive Cancer Network, 2021 Pancreatic cancer is the fourth leading cause of cancer-related death among men and women in the United States. A major challenge in treatment remains patients' advanced disease at diagnosis.M. Tempero, M. Malafa, M. Al-Hawary, S. Behrman, A. Benson, D. Cardin, E. Chiorean, V. Chung, B. Czito, M. Del Chiaro, M. Dillhoff, T. Donahue, E. Dotan, C. Ferrone, C. Fountzilas, J. Hardacre, W. Hawkins, Kelsey A Klute, A. Ko, J. Kunstman, N. Loconte, A. Lowy, C. Moravek, E. Nakakura, A. Narang, Jorge V. Obando, Patricio M. Polanco, S. Reddy, M. Reyngold, C. Scaife, Jeanne Shen, C. Vollmer, R. Wolff, B. Wolpin, B. Lynn, Giby V. George +35 moresemanticscholar +1 more sourceAdenocarcinoma of the lung [PDF]
Thorax, 1969 The clinical and histological features of 53 cases of adenocarcinoma of the lung are presented. In more than one-third of the patients the tumour was a solitary nodule, raising the possibility that it might be a metastatic focus. Although histological features may suggest an origin from such sources as the kidney, uterus, ovary or bowel, nearly all ...J R, Hinds, G C, Hitchcockopenaire +2 more sourcesAdenocarcinoma of the cervix [PDF]
Cancer, 2002 The current study examines 1) the sensitivity of detection of invasive adenocarcinoma of the cervix in a routine cervical screening service, and 2) the frequency in smears of cytologic criteria previously found to be useful in diagnosis.Data on women with diagnoses of adenocarcinoma of the cervix accessioned at the Western Australian Cervical Cytology ...Meike, Schoolland, Stephen, Allpress, Gregory F, Sterrett +2 moreopenaire +2 more sourcesA human lung tumor microenvironment interactome identifies clinically relevant cell-type cross-talk. [PDF]
, 2020 BackgroundTumors comprise a complex microenvironment of interacting malignant and stromal cell types. Much of our understanding of the tumor microenvironment comes from in vitro studies isolating the interactions between malignant cells and a single ...Azizi, Armon, Bejnood, Alborz, Bouchard, Gina, Diehn, Maximilian, Feng, Weiguo, Forgó, Erna, Gentles, Andrew J, Hoang, Chuong D, Hui, Angela Bik-Yu, Jeong, Youngtae, Knowles, David A, Kuong, Amanda, Nair, Ramesh V, Nair, Viswam S, Plevritis, Sylvia K, van de Rijn, Matt, Varma, Sushama, West, Rob, Xu, Yue, Yu, Alice +19 morecore +4 more sourcesMultiple Omics Analysis of the Role of RBM10 Gene Instability in Immune Regulation and Drug Sensitivity in Patients with Lung Adenocarcinoma (LUAD)
Biomedicines, 2023 Objective: The RNA-binding protein RBM10 can regulate apoptosis during the proliferation and migration of pancreatic cancer, endometrial cancer, and osteosarcoma cells; however, the molecular mechanism underlying lung adenocarcinoma is rarely reported ...Liusheng Wu, Qi Liu, X-J Ruan, Xinyu Luan, Yanfeng Zhong, Jixian Liu, Jun Yan, Xiaoqiang Li +7 moresemanticscholar +1 more source
