Results 31 to 40 of about 672,479 (309)
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Combination of gastric atrophy, reflux symptoms and histological subtype indicates two distinct aetiologies of gatric cardia cancer. [PDF]
, 2008 <b>INTRODUCTION</b> Atrophic gastritis is a risk factor for non-cardia gastric cancer, and gastro-oesophageal reflux disease (GORD) for oesophageal adenocarcinoma.
Didevar, R. +11 more
core +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
PD-L1 expression in squamous-cell carcinoma and adenocarcinoma of the lung
Radiology and Oncology, 2017 With introduction of immunotherapy (IT) into the treatment of advanced non-small-cell lung cancer (NSCLC), a need for predictive biomarker became apparent. Programmed death ligand 1 (PD-L1) protein expression is most widely explored predictive marker for
Janzic Urska +4 more
doaj +1 more source
Small Bowel Adenocarcinoma Presenting with Brain Metastasis
Turkish Journal of Colorectal Disease, 2020 Although the small bowel (SB) comprises majority of the length of alimentary tract and its surface mucosal area, adenocarcinoma of SB is rare in comparison to other gastrointestinal malignancies.
Isra Al Jorani, Özgen Işık
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
The Annals of African Surgery, 2013 Urachal adenocarcinoma is a rare tumor and represents 0.17–0.34% of all bladder tumors. Most of the reported cases are in western literature and to the best of our knowledge this is the first case report of urachal adenocarcinoma in sub-Saharan Africa ...
s nguku +3 more
doaj
Lung adenocarcinoma with mixed solid and crazy‐paving appearances
Clinical Case Reports, 2021 “Crazy paving” on CT images refers to the superimposition of ground‐glass opacity and linear pattern resembling irregularly shaped paving stones. Initially, “crazy paving” was described as a pathognomonic sign of alveolar proteinosis.
Roqiah Fatmawati Abdul Kadir +3 more
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Turkish Journal of Colorectal Disease, 2020 Aim:Acute appendicitis is the most common cause of emergency abdominal surgery in the world. Although the etiology of appendicitis is still not fully known, possible causes include lumen obstruction.
Ufuk Uylaş +4 more
doaj +1 more source