Results 51 to 60 of about 1,201,752 (348)

MAP17 predicts sensitivity to platinum-based therapy, EGFR inhibitors and the proteasome inhibitor bortezomib in lung adenocarcinoma [PDF]

, 2018
Background The high incidence and mortality of lung tumours is a major health problem. Therefore, the identification both of biomarkers predicting efficacy for therapies in use and of novel efficacious therapeutic agents is crucial to increase patient ...
Carnero Moya, Amancio, Ferrer, Irene, García Heredia, José Manuel, Molina Pinelo, Sonia, Pérez, Marco, Quintanal Villalonga, Álvaro Diego   +5 more
core   +1 more source

Detection of liver metastases in patients with pancreatic adenocarcinoma: MRI versus CT. [PDF]

Batna Journal of Medical Sciences
Introduction. Detection of liver metastases is important to guide therapeutic management of pancreatic cancer. Data suggest that magnetic resonance imaging (MRI) is more sensitive than computed tomography (CT) for the diagnosis of liver metastases ...
Walid TIBERMACINE, Mohamed Redha SAKER, Raouf MENOURA, Redha BOUZINOUNA, Abdelaziz AMMARI, Mustapha BOUMENDJEL, Sana Hazar TACHOUR   +6 more
doaj   +1 more source

MicroRNA co-expression networks exhibit increased complexity in pancreatic ductal compared to Vater’s papilla adenocarcinoma [PDF]

, 2017
iRNA expression abnormalities in adenocarcinoma arising from pancreatic ductal system (PDAC) and Vater’s papilla (PVAC) could be associated with distinctive pathologic features and clinical cancer behaviours.
Andriulli, Angelo, Biagini, Tommaso, Capocefalo, Daniele, Carella, Massimo, Copetti, Massimiliano, De Bonis, Antonio, Di Sebastiano, Pierluigi, Francesco Di Mola, Fabio, Fusilli, Caterina, Maiello, Evaristo, Mastrodonato, Nicola, Mazza, Tommaso, Pazienza, Valerio, Piepoli, Ada, Tavano, Francesca   +14 more
core   +1 more source

Features of lymph node metastasis depending on intratumoral heterogeneity of non-small cell lung cancer in patients with different morphological changes in the bronchial epithelium

Сибирский онкологический журнал, 2022
The aim of the study: to examine the relationship between the morphological diversity of non-small cell lung cancer and the frequency of lymph node metastasis in groups of patients with different epithelial conditions in the bronchi adjacent to the tumor.
M. V. Zavyalova, D. M. Loos, D. S. Pismenny, A. A. Durova, E. S. Andryukhova, E. O. Rodionov, S. V. Miller, S. A. Tuzikov, O. V. Pankova, L. A. Tashireva, S. V. Vtorushin, V. M. Perelmuter   +11 more
doaj   +1 more source

Genomic characterization of human brain metastases identifies drivers of metastatic lung adenocarcinoma

Nature Genetics, 2020
Brain metastases from lung adenocarcinoma (BM-LUAD) frequently cause patient mortality. To identify genomic alterations that promote brain metastases, we performed whole-exome sequencing of 73 BM-LUAD cases.
D. Shih, D. Shih, Naema Nayyar, Ivanna V. Bihun, Ivanna V. Bihun, I. Dagogo-Jack, C. Gill, C. Gill, Elisa Aquilanti, Elisa Aquilanti, Mia S Bertalan, Alexander Kaplan, M. D’Andrea, U. Chukwueke, F. M. Ippen, Christopher A. Alvarez-Breckenridge, Nicholas D. Camarda, Matthew Lastrapes, D. McCabe, D. McCabe, Benjamin M Kuter, B. Kaufman, B. Kaufman, M. Strickland, J. Martinez-Gutierrez, J. Martinez-Gutierrez, Deepika Nagabhushan, Magali De Sauvage, Michael D. White, Brandyn Castro, Kaitlin Hoang, Andrew Kaneb, Emily Batchelor, S. Paek, S. H. Park, M. Martinez-Lage, A. Berghoff, Parker Merrill, E. Gerstner, T. Batchelor, M. Frosch, Ryan P. Frazier, D. Borger, A. Iafrate, B. Johnson, S. Santagata, S. Santagata, M. Preusser, D. Cahill, S. Carter, P. Brastianos, P. Brastianos   +51 more
semanticscholar   +1 more source

Uncovering Adrenal Incidentalomas – the role of imaging methods in diagnostic process

Journal of Education, Health and Sport
Introduction and purpose An adrenal incidentaloma is any lesion found unexpectedly during an imaging study performed for an unrelated reason. The detection rate of incidental adrenal tumors is steadily increasing.
Małgorzata Matuszek, Magdalena Woźniak, Wiktor Biłat   +2 more
doaj   +1 more source

A rare clinical case of a patient with mixed neuroendocrine-non-neuroendocrine neoplasms of the ampulla of vater

Сибирский онкологический журнал, 2023
Background. Neuroendocrine tumors are rare neoplasias accounting for 1 % of all digestive malignancies. In 2010, mixed neuroendocrine-non-neuroendocrine neoplasms (MiNENs) were classified by the World Health Organization This type of tumor is extremely ...
E. S. Drozdov, M. Yu. Grishchenko, V. I. Kharitonkin, N. I. Lyan, O. Yu. Borodin, E. A. Fesik, A. G. Korotkevich   +6 more
doaj   +1 more source

Treatment utilization and outcomes in elderly patients with locally advanced esophageal carcinoma: A review of the National Cancer Database [PDF]

, 2017
For elderly patients with locally advanced esophageal cancer, therapeutic approaches and outcomes in a modern cohort are not well characterized. Patients ≥70 years old with clinical stage II and III esophageal cancer diagnosed between 1998 and 2012 were ...
Bradley, Jeffrey D, Kozower, Benjamin, Lockhart, A. Craig, Meyers, Bryan F, Parikh, Parag J, Perkins, Stephanie M, Puri, Varun, Roach, Michael C, Robinson, Cliff G, Samson, Pamela P, Vlacich, Gregory   +10 more
core   +2 more sources

Virtual microdissection identifies distinct tumor- and stroma-specific subtypes of pancreatic ductal adenocarcinoma

Nature Genetics, 2015
Pancreatic ductal adenocarcinoma (PDAC) remains a lethal disease with a 5-year survival rate of 4%. A key hallmark of PDAC is extensive stromal involvement, which makes capturing precise tumor-specific molecular information difficult.
Richard A Moffitt, Raoud Marayati, Elizabeth L Flate, Keith E. Volmar, S. G. H. Loeza, K. Hoadley, N. Rashid, Lindsay A. Williams, Samuel C. Eaton, Alexander H. Chung, Jadwiga K Smyla, Judy M. Anderson, Hong Jin Kim, D. Bentrem, M. Talamonti, C. Iacobuzio-Donahue, Michael A. Hollingsworth, Jen Jen Yeh   +17 more
semanticscholar   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source