Results 61 to 70 of about 672,479 (309)

GWAS meta-analysis of 16 790 patients with Barrett\u2019s oesophagus and oesophageal adenocarcinoma identifies 16 novel genetic risk loci and provides insights into disease aetiology beyond the single marker level

, 2022
: Objective Oesophageal cancer (EC) is the sixth leading cause of cancer-related deaths. Oesophageal adenocarcinoma (EA), with Barrett\u2019s oesophagus (BE) as a precursor lesion, is the most prevalent EC subtype in the Western world. This study aims to
Thieme, Rene, Maj, Carlo, Gehlen, Jan, Yogesh Vashist, Ines Gockel, M\ufcller, Michaela, H\uf6lscher, Arnulf H., Weism\ufcller, Josef, Rösch, Thomas, May, Sandra, Gerges, Christian, Messmann, Helmut, Arne Dietrich, B\uf6hmer, Anne C., Barrett's and Esophageal Adenocarcinoma Consortium (BEACON), Ebigbo, Alanna, Daniel Reim, Christiane J Bruns, Ong, Jue-Sheng, Jue-Sheng Ong, David Ellinghaus, Lang, Hauke, Dani Dakkak, Laura Chegwidden, Vaughan, Thomas L., Julian Reingruber, Sandra May, Weismüller, Josef, Franke, Andre, Vieth, Michael, Ellinghaus, David, Thomas L Vaughan, Görg, Siegfried, Ian Tomlinson, Dominik Heider, Hohaus, Michael, Jennis Kandler, null null, Hölscher, Arnulf H, Speller, Jan, Udo Benner, Whiteman, David C., Hoffmeister, Albrecht, Prenen, Hans, Alanna Ebigbo, Lordick, Florian, Chegwidden, Laura, Vaughan, Thomas L, Bruns, Christiane J., Dommermuth, Jens, Schmidt, Carsten, Schr\uf6der, Julia, Florian Lordick, Borisov, Oleg, G\uf6rg, Siegfried, Fuchs, Claudia, Kandler, Jennis, Andreas Mayr, David C Whiteman, Andrea May, Nöthen, Markus M, Dakkak, Dani, Rene Thieme, Janusz Jankowski, Stuart MacGregor, Matthew F Buas, Müller, Michaela, Tomlinson, Ian, Jan Gehlen, N\uf6then, Markus M., Bruns, Christiane J, Michael Vieth, Schumacher, Brigitte, Lothar Veits, Puya Gharahkhani, Lyros, Orestis, Böhmer, Anne C, Michaela Müller, Helmut Messmann, Horst Neuhaus, Jankowski, Janusz, Julia Schröder, Grimminger, Peter P, Thomas Schmidt, Christian Gerges, Thrift, Aaron P., Jan Speller, Dietrich, Arne, Kreuser, Nicole, Arnulf H Hölscher, Sara Galavotti, Reim, Daniel, Wissinowski, Thaddäus T, Aaron P Thrift, Neuhaus, Horst, Gockel, Ines, Rebecca Claire Fitzgerald, Palles, Claire, Hillmer, Axel M., Orestis Lyros, Josef Weismüller, May, Andrea, Claudia Fuchs, Matthias Mehdorn, Benner, Udo, Esophageal Adenocarcinoma Genetics Consortium (EAGLE), Marino Venerito, Nicole Kreuser, Schmidt, Thomas, Grimminger, Peter P., Thaddäus T Wissinowski, Vashist, Yogesh, Whiteman, David C, Schröder, Julia, Venerito, Marino, Heider, Dominik, Wissinowski, Thadd\ue4us T., Thomas Rösch, Johannes Schumacher, Thrift, Aaron P, Oleg Borisov, Carsten Schmidt, Anne C Böhmer, Peter P Grimminger, Stocker, Gertraud, Brigitte Schumacher, Hillmer, Axel M, Jens Dommermuth, Hess, Timo, Claire Palles, Mehdorn, Matthias, R\uf6sch, Thomas, Gharahkhani, Puya, Jing Dong, Veits, Lothar, Buas, Matthew F, Timo Hess, Reingruber, Julian, Hauke Lang, Markus M Nöthen, Hakan Alakus, Michael Hohaus, Galavotti, Sara, Andre Franke, Schumacher, Johannes, Axel M Hillmer, Wellcome Trust Case Control Consortium 2 (WTCCC2), Albrecht Hoffmeister, Mayr, Andreas, Carlo Maj, Alakus, Hakan, MacGregor, Stuart, Siegfried Görg, Dong, Jing, Gertraud Stocker, Buas, Matthew F., Fitzgerald, Rebecca Claire   +156 more
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Isolation of Streptococcus bovis in a Patient with Undiagnosed Colon Cancer. A Case Report

Medisur, 2014
One of the bacterial agents commonly associated with colorectal cancer is Streptococcus bovis. Twenty five to 80 % of patients with Streptococcus bovis bacteremia develop colorectal tumors and the incidence of colonic neoplasia associated with S.
Ledys Pérez Morales, Jorge Emilio Barletta del Castillo, Odette Quiñones Cherta   +2 more
doaj  

Adenocarcinoma of the cervix [PDF]

Cancer, 2002
The current study examines 1) the sensitivity of detection of invasive adenocarcinoma of the cervix in a routine cervical screening service, and 2) the frequency in smears of cytologic criteria previously found to be useful in diagnosis.Data on women with diagnoses of adenocarcinoma of the cervix accessioned at the Western Australian Cervical Cytology ...
Meike, Schoolland, Stephen, Allpress, Gregory F, Sterrett   +2 more
openaire   +2 more sources

RNA Interference-Mediated Gene Silencing in Esophageal Adenocarcinoma

, 2018
RNA interference (RNAi) is a normal physiological mechanism in which a short effector antisense RNA molecule regulates target gene expression. It is a powerful tool to silence a particular gene of interest in a sequence-specific manner and can be used to
Islam, F, Lam, AK, Gopalan, Vinod, Lam, Alfred, Farhadul Islam, Islam, Md. Farhadul, Vinod Gopalan, Gopalan, V, Alfred K. Lam   +8 more
core   +1 more source

Prospective, open, multi-centre phase I/II trial to assess safety and efficacy of neoadjuvant radiochemotherapy with docetaxel and oxaliplatin in patients with adenocarcinoma of the oesophagogastric junction [PDF]

, 2013
Background: This phase I/II-trial assessed the dose-limiting toxicities (DLT) and maximum tolerated dose (MTD) of neoadjuvant radiochemotherapy (RCT) with docetaxel and oxaliplatin in patients with locally advanced adenocarcinoma of the oesophagogastric ...
Klautke, Gunther, Galle, Peter R., Brenner, Baruch, Arnold, Dirk, Roessler, Hans-Peter, Thomaidis, Thomas, Schimanski, Carl Christoph, Schmidberger, Heinz, Rödel, Claus, Gockel, Ines, Möhler, Markus, Trarbach, Tanja, Lang, Hauke   +12 more
core   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Analysis of the Clinicopathologic Characteristics of Lung Adenocarcinoma With CTNNB1 Mutation

Frontiers in Genetics, 2020
IntroductionLung adenocarcinoma with CTNNB1 mutation is relatively uncommon, and its clinicopathologic characteristics, disease course, and prognosis have not been well-studied.MethodsA total of 564 lung adenocarcinoma patients were enrolled in this ...
Chao Zhou, Chao Zhou, Wentao Li, Jinchen Shao, Jikai Zhao, Chang Chen   +5 more
doaj   +1 more source

Chemotherapy for Esophageal Adenocarcinoma

, 2018
Esophageal and esophagogastric junction adenocarcinoma is a distinct entity from esophageal squamous cell carcinoma with respect to etiology and biology despite sharing the same anatomical location. While most international treatment guidelines recommend
Lam, KO, Dora L. W. Kwong, Ka-On Lam, Kwong, DLW   +3 more
core   +1 more source

A CASE REPORT OF PAPILLARY ADENOCARCINOMA IN SUBLINGUAL REGION: ULTRASTRUCTURAL AND HISTOCHEMICAL STUDY [PDF]

, 1989
A rare case of papillary adenocarcinoma located in the sublingual region is presented. This case was initially considered to be a hemangioma and then the tentative clinical diagnosis was thyroglossal duct cyst at the time of the operation under general ...
Koji, KINO, Nobuyuki, TANAKA, Hiroyasu, MIYAMOTO, Kuo, Jeng HSIEH, Teruo, AMAGASA, Shigetoshi, SHIODA, Toshiyuki, IZUMO, Kenji, HASHIMOTO   +7 more
core   +1 more source