An investigation of the progression from Barrett's esophagus to adenocarcinoma [PDF]
Barrett's esophagus is a metaplasia of the epithelium of the lower esophagus from a normal squamous appearance to a columnar appearance more typically found in the stomach. It is normally caused by prolonged gastric reflux. While Barrett's esophagus is
Palmese, Scott Joseph
core +1 more source
The molecular basis for ethnic variation and histological subtype differences in prostate cancer. [PDF]
Prostate cancer is a common malignancy among men in Western countries. Recently the morbidity and mortality of prostate cancer increase dramatically in several oriental countries including China.
Goldstein, Andrew S +2 more
core +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Lung cancer stands as the most prevalent and deadliest type of cancer, with adenocarcinoma being the most common subtype. Computed Tomography (CT) is widely used for detecting tumours and their phenotype characteristics, for an early and accurate ...
Margarida Gouveia +4 more
doaj +1 more source
Multisystem Langerhans cell histiocytosis coexisting with metastasizing adenocarcinoma of the lung: A case report [PDF]
Introduction. Langerhans cell histiocytosis (LCH) is an uncommon disease of unknown etiology characterized by uncontrolled proliferation and infiltration of various organs by Langerhans cells. Case report. We presented a 54-year-old man, heavy smoker,
Lovrenski Aleksandra +6 more
doaj +1 more source
Metastasis of Colon Adenocarcinoma to Maxillary Gingiva and Palate [PDF]
Introduction: Colon adenocarcinoma is one of the foremost causes of cancer mortality. Oral metastasis of colon adenocarcinoma is, however, rare and indicates an end-stage disease process.
Zohreh Dalirsani +2 more
doaj +1 more source
Pathologist-level classification of histologic patterns on resected lung adenocarcinoma slides with deep neural networks [PDF]
Classification of histologic patterns in lung adenocarcinoma is critical for determining tumor grade and treatment for patients. However, this task is often challenging due to the heterogeneous nature of lung adenocarcinoma and the subjective criteria ...
Jason Wei +5 more
semanticscholar +1 more source
Deciphering cell lineage specification of human lung adenocarcinoma with single-cell RNA sequencing
Lung adenocarcinomas (LUAD) arise from precancerous lesions such as atypical adenomatous hyperplasia, which progress into adenocarcinoma in situ and minimally invasive adenocarcinoma, then finally into invasive adenocarcinoma.
Zhoufeng Wang +18 more
semanticscholar +1 more source
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Excisional treatment in women with cervical adenocarcinoma in situ (AIS): a prospective randomised controlled noninferiority trial to compare AIS persistence/recurrence after loop electrosurgical excision procedure with cold knife cone biopsy: protocol for a pilot study [PDF]
Introduction: Adenocarcinoma in situ (AIS) of the uterine cervix is the precursor to invasive endocervical adenocarcinoma. An excisional biopsy such as a cold knife cone biopsy (CKC) should be performed to exclude invasive adenocarcinoma.
Anderson, Lyndal +15 more
core +2 more sources

