Results 41 to 50 of about 700,882 (308)

Cancer metastasis of an unknown primary location into a postoperative kelody scar after a mine blast wound of the neck

open access: yesPatologìâ
The connection between military trauma and cancer is not sufficiently studied. We present a clinical observation of metastasis of cancer of unknown primary localization into a keloid scar of the neck, which occurred after surgical treatment of a wound ...
O. O. Kovalyov   +4 more
doaj   +1 more source

Introduction: Esophageal Adenocarcinoma: Updates of Current Status

open access: yes, 2018
Esophageal and esophagogastric adenocarcinoma is highly prevalent in the Western populations and is a major cause of cancer-related morbidity and mortality worldwide. The incidence of esophageal adenocarcinoma is rapidly rising in the Western populations.
Lam, AK, Alfred K. Lam
core   +1 more source

A CASE REPORT OF PAPILLARY ADENOCARCINOMA IN SUBLINGUAL REGION: ULTRASTRUCTURAL AND HISTOCHEMICAL STUDY [PDF]

open access: yes, 1989
A rare case of papillary adenocarcinoma located in the sublingual region is presented. This case was initially considered to be a hemangioma and then the tentative clinical diagnosis was thyroglossal duct cyst at the time of the operation under general ...
Koji, KINO   +7 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Target Therapy for Esophageal Adenocarcinoma

open access: yes, 2018
Adenocarcinoma of the esophagus is a deadly disease and median survival of patients with metastatic disease is around 1 year only. There is an unmet need to personalize treatment by identifying molecular targets and respective target therapy in ...
Lam, KO   +3 more
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Urachal Adenocarcinoma

open access: yesThe Annals of African Surgery, 2013
Urachal adenocarcinoma is a rare tumor and represents 0.17–0.34% of all bladder tumors. Most of the reported cases are in western literature and to the best of our knowledge this is the first case report of urachal adenocarcinoma in sub-Saharan Africa ...
s nguku   +3 more
doaj  

Epigenetics: DNA Methylation Analysis in Esophageal Adenocarcinoma

open access: yes, 2018
The aberrant DNA methylation has been noted to occur at promoter of tumor suppressor, cell adhesion, DNA repair, and other growth regulating genes during the progression of nonneoplastic esophageal mucosa to Barrett esophagus to esophageal adenocarcinoma.
Johnny C. Tang   +7 more
core   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Comparative study of imaging and pathology of primary mucinous adenocarcinoma with different imaging manifestations

open access: yesThe Clinical Respiratory Journal
Background Pulmonary mucinous adenocarcinoma is a special type of lung cancer. Its imaging manifestations are diverse, which brings challenges to clinical diagnosis. However, its formation mechanism is unclear. Objective The objective of this study is to
Jun Han   +9 more
doaj   +1 more source

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