Results 71 to 80 of about 1,201,752 (348)

Pancreatic Ductal Adenocarcinoma: Epidemiology and Risk Factors

Diagnostics, 2021
The number of new cases of pancreatic ductal adenocarcinoma is increasing with a cumulative total of 495,773 cases worldwide, making it the fourteenth most common malignancy.
J. Ushio, A. Kanno, Eriko Ikeda, Kozue Ando, Hiroki Nagai, Tetsurou Miwata, Yuki Kawasaki, Y. Tada, Kensuke Yokoyama, Norikatsu Numao, K. Tamada, A. Lefor, H. Yamamoto   +12 more
semanticscholar   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, Volume 20, Issue 6, Page 1591-1611, June 2026.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Primary pancreatic peripheral T‐cell lymphoma‐not otherwise specified mimicking acute pancreatitis: A case report and review of literature

Clinical Case Reports
Key Clinical Message Primary pancreatic lymphoma is a rare disease that can mimic acute pancreatitis. Since the prognosis and approaches differ, clinicians should differentiate it from other pancreatic diseases, especially autoimmune pancreatitis and ...
Fatemeh Zarimeidani, Rahem Rahmati, Elahe Meftah, Maryam Soheilipour   +3 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Urachal Adenocarcinoma

The Annals of African Surgery, 2013
Urachal adenocarcinoma is a rare tumor and represents 0.17–0.34% of all bladder tumors. Most of the reported cases are in western literature and to the best of our knowledge this is the first case report of urachal adenocarcinoma in sub-Saharan Africa ...
s nguku, Twahirwa N, rukaria p, Etabale J, Githae F, Tharao M.   +3 more
doaj  

PD-L1 expression in squamous-cell carcinoma and adenocarcinoma of the lung

Radiology and Oncology, 2017
With introduction of immunotherapy (IT) into the treatment of advanced non-small-cell lung cancer (NSCLC), a need for predictive biomarker became apparent. Programmed death ligand 1 (PD-L1) protein expression is most widely explored predictive marker for
Janzic Urska, Kern Izidor, Janzic Andrej, Cavka Luka, Cufer Tanja   +4 more
doaj   +1 more source

Small Bowel Adenocarcinoma Presenting with Brain Metastasis

Turkish Journal of Colorectal Disease, 2020
Although the small bowel (SB) comprises majority of the length of alimentary tract and its surface mucosal area, adenocarcinoma of SB is rare in comparison to other gastrointestinal malignancies.
Isra Al Jorani, Özgen Işık
doaj   +1 more source

Dry Small Pleural Dissemination of Adenocarcinoma of the Lung Preoperatively Detected by PET/CT: A Report of Two Cases [PDF]

, 2008
Dry pleural dissemination in non-small cell lung cancer, defined as solid pleural metastasis of lung cancer without pleural eff usion, is a condition occurring in T4 lung cancer.
Aoe, Motoi, Date, Hiroshi, Okutani, Daisuke, Oto, Takahiro, Sano, Yoshifumi, Toyooka, Shinichi, Yamane, Masaomi   +6 more
core   +1 more source

Cell death-based treatment of lung adenocarcinoma

Cell Death and Disease, 2018
The most common type of lung cancer is adenocarcinoma (ADC), comprising around 40% of all lung cancer cases. In spite of achievements in understanding the pathogenesis of this disease and the development of new approaches in its treatment, unfortunately,
T. Denisenko, I. Budkevich, B. Zhivotovsky   +2 more
semanticscholar   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, Volume 20, Issue 6, Page 1494-1512, June 2026.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source