Results 71 to 80 of about 672,479 (309)
Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong +6 morewiley +1 more sourceTumor-associated microbiome features of metastatic colorectal cancer and clinical implications
Frontiers in OncologyBackgroundColon microbiome composition contributes to the pathogenesis of colorectal cancer (CRC) and prognosis. We analyzed 16S rRNA sequencing data from tumor samples of patients with metastatic CRC and determined the clinical implications.Materials ...Ho Jung An, Ho Jung An, Mira A. Partha, HoJoon Lee, Billy T. Lau, Dmitri S. Pavlichin, Alison Almeda, Anna C. Hooker, Giwon Shin, Hanlee P. Ji, Hanlee P. Ji +10 moredoaj +1 more sourceProstate adenocarcinoma
, 2005 Slide shows a 20X image of prostate adenocarcinoma, Gleason grade 3, Score 6 infiltrating between benign prostate glands.core Detection and Quantification of MicroRNAs in Esophageal Adenocarcinoma
, 2018 MicroRNAs (miRNAs) are a class of small, noncoding RNAs that have been emerging as novel regulators in esophageal adenocarcinoma. Their role has been established in various aspects of esophageal adenocarcinoma including carcinogenesis, progression ...Islam, F, Lam, AK, Amin, Moein, Gopalan, Vinod, Lam, Alfred, Moein Amin, Farhadul Islam, Amin, M, Islam, Md. Farhadul, Vinod Gopalan, Gopalan, V, Alfred K. Lam +11 morecore +1 more sourceDocetaxel versus active symptom control for refractory oesophagogastric adenocarcinoma (COUGAR-02) : an open-label, phase 3 randomised controlled trial [PDF]
, 2013 Background:
Second-line chemotherapy for patients with oesophagogastric adenocarcinoma refractory to platinum and fluoropyrimidines has not shown benefits in health-related quality of life (HRQoL). We assessed whether the addition of docetaxel to active Cliona C Kirwan (10530920), Burnett, Alan K., Carmichael, Amtul, Neal, Richard D, Mallon, Elizabeth, Greenhalf, W, Faria, Claudia C., Wen, Patrick Y, Murray, G, Hickish, T, Dommett, R., Berendsen, A, Fareeda Coxon, Greenhalf, William, Torchia, Jonathon, Patricia Fairbrother (10530899), Harvey, J, Evans, A, de Wit, Niek, Janowitz, T., Dunkel, Ira J, Martin, Paul, Waters, Justin S., Skene, Anthony, Roques, Tom, Camilla Zimmermann, Wildiers, Hans, Benson, JR, A Goyal (7752236), Grech, Angela, Voruganti, Teja, Bridgewater, J. A., Wilkinson, Clare, Kefford, Richard, Whitlock, J., Eatock, M, Wataya, Takafumi, Holcombe, Chris, Trimboli, R.M., Walker, J, Wardle, Jane, Barakzai, Muhammad Abrar, Morden, James, S Michael Crawford, Evans, J, Horgan, K, Falk, S., Madhusudan, S., Watson, E., Benson, John R, J. S. Waters (7644221), Ford, Hugo E R, Palmer, DH, Kilburn, L, McIntosh, SA, Jones, Gail, Neoptolemos, JP, CC Kirwan (7752239), Hiom, S, Reeve, B.B., Colver, Graham B, Franceschi, Enrico, Wender, R, Chan, Jennifer A, Rueda, Oscar M., K. Morris (7644206), Peake, M, Kim, Seung-Ki, Sisler, J, SMaRT (Symptom Management Research Trials) Oncology-3 Team, D. Cunningham (2534575), Hauser, Peter, Stephen Taplin, Friis, Lone, Horgan, Kieran, Sussman, J, Kyte, Derek, Taplin, Stephen, Hiom, S., Hills, Robert K, Ross, Paul J., Charlotte Rawcliffe, Van Meter, Timothy E., Soto-Perez-de-Celis, E., Emery, Jon, Cunningham, D., Strother, Douglas, RI Cutress (7705409), Mitchell, Geoffrey, Cox, T, Cox, Trevor, Archer, Caroline, Anthoney, DA, Raghavan Vidya (10530911), Evans, Anthony G., Glas, N.A. de, Warren, Katherine E, Nicolson, Marianne, Evans, Anthony, Hongeng, Suradej, MacDonald, Tobey J, Currow, DC, Ellis, Ian O., Rees, Robert C., Anthony Evans, Schueller, Ulrich, Morgan, Yvonne G, Hunter, Ann, Greenhalf, W., Wadd, N., Hukin, Juliette, Burnett, Alan K, Hawkins, Cynthia E, Mason, R., Harrison, M, Kirwan, C, Benn, K., Hortobágyi, Tibor, Cutress, Ramsey I, Aapro, MS, William Greenhalf, Bridgewater, JA, Ball, Graham R., Taplin, S., Aapro, Matti S., Kirkwood, John M., Lorigan, Paul; id_orcid, Wardle, J., Peter Vedsted, S. Madhusudan (6554321), Wadsley, J, Benn, Karen, Chan, Stephen Y.T., Wadd, N, Grassi, L., Eva Grunfeld, Cook, Natalie; id_orcid, Nanson, Gemma, McAdam, Karen, Judkins, Alexander R., Georgios Lyratzopoulos, Propper, D., Phillips, Joanna, A. Lopes (7644197), Haworth, Kellie B, Kilburn, Lucy, Ramsey I. Cutress (12375363), Sharpe, Michael, Dodson, Andrew, Cunningham, D., Marshall, Andrea, Ho, King Ching, Eatock, Martin, Cheung, Kwok-Leung, Zimmermann, C, Ford, H. E., Blazeby, Jane M, Bognár, Laszló, Valle, J, Roque, Lucia, Lee, Sandra J., Campbell, Fiona, Lyratzopoulos, Georgios, JS Vaidya (7752254), Gourley, C, Cunningham, David, Richard Wender, Dodson, A, Johnston, Donna, Wadd, Nick, Costello, E, Ponti, A., Neal, Richard D., Gupta, S, Rawcliffe, Charlotte L., Srinivasan Madhusudan, Evans, Abigail, Cardoso, Maria-Joao, Van Meter, Timothy E, Hills, Robert K., Wasan, H., Dive, C, Wender, R., Palmer, Daniel H, Mason, R, Dive, Caroline, Neoptolemos, John, Lyratzopoulos, G, Harvey, James, Hunter, D., Fangusaro, Jason R., Lafay-Cousin, Lucie, Ross, P., Calvert, Melanie, Abernethy, AP, Fangusaro, Jason R, Ozolins, Mara, Anthoney, Alan, Armstrong, Sarah J., Palmer, Daniel H., Ross, PJ, Jabado, Nada, Marshall, A. (Andrea), Costello, Eithne, S Potter (7655408), Propper, D, Mata-Mbemba, Daddy, Association Of Breast Surgery Surgical Gap Analysis Working Group, Sisler, J., Sussman, Jonathan, Evans, Jeff, Niek de Wit, Jeremy Whelan, James Harvey (6581414), Colver, Graham B., Korc-Grodzicki, B, Sibbering, M, Korc-Grodzicki, B., Kaur, Geetinder, Zimmerman, C, Wall, Lucy, Pippa Corrie, Cheang, M, Amit Goyal (2678353), Corrie, Pippa, Earle, Craig, Grunfeld, E, Michael Peake, Perkins, William, Emery, J., de Glas, Nienke Aafke, Peake, Michael, Will P. Steward (7644224), Robertson, John, Shaw, Victoria, Middleton, G., Tamrazi, Benita, Macleod, U, Judkins, Alexander R, Cox, T., Long, Georgina V, Ng, Ho-keung, Walker, Jane, Beare, S, Hiom, Sara, Trevor Cox, JR Benson (7752260), Kaur, G., Biganzoli, L., Hunter, D, Hamilton, W, P. J. Ross (7644218), Vezina, Gilbert, Silcocks, P, Peake, M., Brain, EGC, Nicolaides, Theodore, Association of Breast Surgery Surgical Gap Analysis Working Group (7752266), Naisbitt, Dean, John P Neoptolemos, Blazeby, J. M., Una Macleod, Neoptolemos, J.P., Russell, Nigel H, Middleton, G, Xu, Bing, Grimwade, David, Waters, JS, Smith, Ian, Crawford, SM, Cardoso, M.J., Zielenska, Maria, Sin-Chan, Patrick, Mitchell, G., Middleton, Gary W., Voruganti, T, Steward, WP, Dowsett, Mitch, Gupta, S., AR Carmichael (7752248), SA McIntosh (7752233), Amtul R. Carmichael (16671834), Backen, Alison C., Wasan, Harpreet, Ross, R. Paul, Iveson, Tim, Whelan, J, Bowen, David, Jeff Sisler, Symeonides, Stefan, Ross, Paul J, Chan, Tiffany Sin Yu, Dunn, J. A., Zimmermann, Camilla, Seifert, B, Bliss, Judith M, Carret, Anne-Sophie, Campbell, F., Eisenstat, David D., Kirwan, Cliona C., Cheang, Maggie, Cook, Natalie, Tihan, Tarik, Roland, M., Shaw, Victoria E, Coxon, Fareeda Y., Symeonides, S, Ross, P, Macleod, Una, Baskin, Berivan, Wender, Richard, Garcia-Alonso, A, de Wit, N, Patel, Poulam M, Coxon, Fareeda Y, Backen, AC, Voruganti, T., Ascierto, Paolo A., Lyratzopoulos, G., Morden, J, Ascierto, Paolo A, McMullin, Mary Frances, Clark, Richard E, Flaherty, Keith T., McIntosh, Stuart A., Steward, W, Russell, Roslin, Goyal, Amit, Kunkler, I.H., Fahey, T, Anthoney, D Alan, Vaidya, Jayant S., Vidya, Raghaven, R Vidya (7752251), Tsang, Janice, Richard D Neal, Banerji, J, Smith, I, Grunfeld, E., Valle, J.W., Jonathan Wadsley, Eisenstat, David D, Basch, Ethan, Ra, Young-Shin, Carmichael, Amtul R., Mitchell, G, Maclead, U, Whitlock, James, John R Benson (16266674), Schüller, Ulrich, Wilcox, M, Stuart A. McIntosh (5693006), J Harvey (7752242), Lok, Jennie, Sisler, Jeff, Nakamura, Hideo, Sara Hiom, Anthoney, A, Neoptolemos, John P, Jon Emery, Pimentel, José, Marotti, L, Berendsen, A., Klekner, Almos, Maraveyas, Anthony, Jayant S. Vaidya (14979294), Bliss, JM, Weller, D., Duus, EM, Biganzoli, Laura, Rubin, G., Middleton, Gary, Malcolm Reed (4465876), Martin, P, Rachel Dommett, Fryer, Chris, Emery, J, Steward, William, D. A. Anthoney (7644212), Srinivasan, Narayanan, Cunningham, D, Amtul R Carmichael (16266668), Crawford, S. Michael, Vidya, Raghavan, David Weller, Albrecht, Steffen, Mansoor, W., Kirwan, Cliona, Teja Voruganti, Friend, J, Roland, M, Banerji, Jane, Iveson, T, Gary Middleton, Dirks, Peter, Soto-Perez-de-Celis, E, Grundy, Richard G., Mueller, Sabine, Birks, Diane, Fearon, KC, Francis, A, Coxon, Fareeda, Fairbrother, Patricia, Maraveyas, A, Marotti, Lorenza, Mason, Robert, Ford, Hugo, Cook, N., Dommett, Rachel, Nicolson, M, Luigi Grassi, Whelan, Jeremy, Potter, S, Hansen, CH, Rutka, James T., McIntosh, Stuart, Dowsett, M, Garami, Miklos, Beare, Sandy, Poussaint, Tina Y, Seifert, Bohumil, Hickish, Tamas, Miller, Paul S J, Lulla, Rishi R, Falk, S., Yan, Y, Goyal, A, de Glas, NA, Jackson, R., Cutress, Ramsey, Sidhu, K, Montpetit, Alexandre, Sumit Gupta, Hamilton, Willie, Craig Earle, Cardoso, M-J, Earle, C, Sharpe, M, Propper, David, Schadendorf, Dirk, Ross, Paul, Caldas, Carlos, Cliona C. Kirwan (3934682), Annette Berendsen, Wilcox, Maggie, Rawcliffe, C., Kunkler, IH, Letourneau, Louis, Gupta, Sumit, Moseley, Paul M., C. Rees (7644227), Brain, Etienne G.C., Colloca, Giuseppe, Wilkinson, CE, Rutkowski, Stefan, Weller, David, Valle, Juan W, Morgan, Paul S, Neoptolemos, J, Silcocks, Paul, Michaud, Jean, J. W. Valle (7644191), Rees, C, Janowitz, Tobias, M. Duggan (7644209), Walter, Fiona, Anthoney, D. Alan, David Propper, Shaw, VE, Warmuth-Metz, Monika, Larbcharoensub, Noppadol, Rawcliffe, Charlotte, A Francis (7752245), Garcia-Alonso, Angel, Soto-Perez-de-Celis, Enrique, Hennig, Michael, Dunham, Christopher P, Marshall, A., Evans, A., Benn, K, Murray, Gordon, Wilkinson, C., Richard Jackson, Juan W Valle, Trimboli, Rubina M., Reed, Malcolm W.R., David Hunter, Daniel H Palmer, Eila Watson, Robertson, J, Holcombe, C, Reed, Malcolm, Waters, Justin S, Duggan, Marian, Douek, M, Shaw, Victoria E., Fahey, T., Cutress, RI, Neal, RD, Fiona Campbell, Falk, S, Sussman, J., Grassi, Luigi, Pietsch, Torsten, Ghaneh, Paula, Wildiers, H., Archer, C, Lu, Jian-Qiang, Hammond, Robert, Carmichael, Amtul R, Williams, Hywel C, Whitlock, J, Wildiers, H, Wilkinson, C, Costello, E., Jackson, R, Vaidya, Jayant S, Berendsen, Annette, Hauschild, Axel, Fults, Daniel, Lopes, A, Battisti, Nicole Matteo Luca, Duggan, M, Agarwal, Devika, Victoria E Shaw, Madhusudan, Srinivasan, Swinson, D., Aapro, M.S., Armstrong, Sarah J, P Fairbrother (7752257), Foreman, Nick, Lorigan, Paul, C. Dive (7594496), Kareclas, Paula, Yip, Stephen, Vidya, R, Tsang, J, Prados, Michael D, Ponti, A, H. Wasan (7644194), Hansen, Christian Holm, Nanson, G, Chau, I., Bath-Hextall, Fiona, Williams, Hywel C., A. C. Backen (7644200), Robert Mason, Grundy, Richard G, Dummer, Reinhard, Dunn, Janet A., Shelley Potter (3405653), Rutka, James T, Shaw, V, Kunkler, Ian H., Dunham, Christopher P., Falk, Stephen, Coxon, F. Y., COUGAR-02 Investigators, Jane Wardle, Brandes, Alba A, Somers, Gino R, Grassi, L, Dommett, R, Corrie, P, Ponti, Antonio, Crawford, S Michael, Mallon, E, Scheineman, Katrin, Whelan, J., Zelcer, Shayna, Bouffet, Eric, Kirwan, CC, Kirwan, Cliona; id_orcid, Valle, Juan W., Seifert, B., Swinson, Daniel, Fairbrother, P, Clare Wilkinson, Tom Fahey, Shaw, V.E., Fahey, Tom, Hunter, David, Wadsley, J., Huang, Annie, Picard, Daniel, Gourley, Charlie, Martin Roland, Cheung, K.L., Adele Francis (16196210), Somers, Gino R., Rao, Arvind, Faria, Claudia C, Fyfe, D., McCartney, Amelia, Brain, E.G.C., Erker, Craig, Hamilton, W., Russell, Nigel H., Wasan, H, Fleming, Adam J., Campbell, F, Fyfe, David, Harrison, Mark, Clark, Richard E., Sibbering, Mark, Kareclas, P., Neal, R.D., Cheung, K-L, Lulla, Rishi R., Ghaneh, P., Greg Rubin, Knapper, Steve, Morris, Karen, Goldman, Stewart, James Whitlock, Ramsay, David A, Benson, John, Fiona Walter, Calvert, M., Maclead, U., Blazeby, Jane M., McArthur, Grant, Colloca, G., Vaidya, Jayant, Ghaneh, P, Wadsley, Jonathan, Kell, Jonathan, Kirwan, Cliona C, Jaspan, Tim, Miller, Paul S.J., Ramsay, David A., Vaidya, JS, Valle, JW, Nick Wadd, Liu, Dong-Xu, Chau, Ian, Stephens, Derek, P. Corrie (3534860), Walter, F, Reed, MWR, Corrie, P., Liu, Karen, Kyte, D., Long, Georgina V., Malcolm W. R. Reed (8115854), Rawcliffe, R, Reeve, Bryce B, Roques, T, Wall, L, Reed, Malcolm W R, Jonathan Sussman, Baskin, Berivan,, Rawcliffe, C, Potter, Shelley, Abdel-Fatah, Tarek M.A., Tamas Hickish, Bliss, Judith M., Rees, Charlotte, Geoffrey Mitchell, Eithne Costello, Ramsey I Cutress (10530917), Hickish, Tamas F., Marotti, L., Zimmerman, C., Vedsted, Peter, Madhusudan, S., A. Maraveyas (7644215), Roland, Martin, Wardle, J, Robinson, Angus, Morgan, Yvonne G., Backen, Alison C, Fried, Iris, Willie Hamilton, Bohumil Seifert, J. A. Bridgewater (7644233), Stuart A McIntosh (10530905), Neoptolemos, John P., Paul Ross, Wadsley, J., Middleton, G. W., Lopes, Andre, Middleton, Gary W, John R. Benson (15213625), Palmer, D.H., Weller, D, Khwaja, Asim, D. H. Palmer (7644203), Robert, Caroline, Harpreet Wasan, Anus, Robinson A, Pockley, Alan G., Wilkinson, C.E., Steward, Will P., Taylor, Michael D., Stephen Falk, Vedsted, P, Colloca, G, McCartney, A., Battisti, NML, O'Day, Steven, Patel, Poulam M., Valle, Juan, Walter, F., Temel, JS, Green, Andrew R., Flaherty, Keith T, Earle, C., Toledano, Helen, McIntosh, Stuart A; id_orcid, MWR Reed (7752263), Rubin, Greg, Bader, Gary D, Jayant S Vaidya (16266671), Hawkins, Cynthia E., Mansoor, Wasat, Vedsted, P., Steward, Will P, Sidhu, Kally, Fleming, Adam J, David Cunningham, de Wit, N., Rubin, G, Srinivasan, Madhusudan, Dunn, Janet A, Lee, Sandra J, S. Beare (7644230), Crawford, S.M., McAdam, K, Watson, Eila, Korc-Grodzicki, Beatriz, Grunfeld, Eva, Bridgewater, John A, Naisbitt, D, Taplin, S, Battisti, N.M.L., Watson, E, Skene, A, Tsang, J., Wilson, Beverly, Carmichael, AR, Jackson, Richard, McIntosh, Stuart A, Bader, Gary D., Kirkwood, John M, Francis, Adele, Mackensen, Andreas, Paula Ghaneh, Sirachainan, Nongnuch, Chan, Jennifer A., Bridgewater, John A., Biganzoli, L, Eggermont, Alexander M M, Coxon, F., de Wit, NJ, Morris, K, Trimboli, RM, Coxon, F, Madhusudan, S, Basch, E., McCartney, A, Taylor, Michael D, Mansoor, Was, Dunn, J, Anthoney, D, Marshall, A, Waters, J, Janowitz, T, Fyfe, D, Ford, H, Bridgewater, J, Chau, I, Robinson, A, Swinson, D, Kareclas, P, Cook, N, Palmer, D, Blazeby, J, Eisenstat D D, Nicolaides T, Bouffet E, Fryer C, Van Meter T E, Fleming A J, Wataya T, Fangusaro J R, Phillips J, Fults D, Johnston D, Albrecht S, Lulla R R, Pimentel J, Hammond R, Ng H -K, Hawkins C E, Picard D, Toledano H, Kim S -K, Yip S, Somers G R, Lafay-Cousin L, Ra Y -S, Dirks P, Zelcer S, Dunham C, Zielenska M, Wilson B, Taylor M D, Judkins A R, Letourneau, Roque L, Birks D, Ramsay D A, Faria C C, Tihan T, Lu J -Q, Rutkowski S, Nakamura H, Strother D, Fried I, Chan J A, Scheineman K, Sirachainan N, Barakzai M A, Bognár L, Rutka J T, Warmuth-Metz M, Foreman N, Jabado N, Hongeng S, Ho K C, Bader G D, Chan T S Y, Sin-Chan P, Larbcharoensub N, Pietsch T, Carret A -S, Grundy R G, Baskin B, Schüller U, Torchia J, Stephens D, Hukin J, Montpetit A, Huang A, Michaud J +845 morecore +2 more sourcesSignificance of High-Mobility Group A Protein 2 Expression in Pancreatic Ductal Adenocarcinoma and Ampullary Adenocarcinoma
, 2023 BACKGROUND/AIMS: Pancreatic and ampullary adenocarcinoma (AAC) are quite resistant to chemotherapy with high metastasis potential. Our study aimed to interpret high-mobility group A protein 2 (HMGA2) expression in benign and precursor pancreatic lesions ...Demir, Lütfiye, Oflas, Damla, Ertuğrul Çolak, Funda Canaz, Çolak, Ertuğrul, Damla Oflas, İlter Özer, Lütfiye Demir, Özer, İlter, Canaz, Funda +9 morecore +1 more sourceEpigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun +9 morewiley +1 more sourceEGFR Mutation Detection in Whole Slide Images of Non‐Small Cell Lung Cancers Using a Two‐Stage Deep Transfer Learning Approach
Cancer MedicineBackground Lung cancer (LC) is the leading cause of cancer death worldwide. Non‐small cell lung cancer is the most frequent and includes adenocarcinoma and squamous cell carcinoma. Currently, LC treatment is based on tumor molecular profiling.Michele Zanoletti, Filippo Ugolini, Laila El Bachiri, Valeria Pasini, Marco Laurino, Francesco De Logu, Eleonora Melissa, Carolina Marchi, Maria Colombino, Daniela Massi, Guido Rindi, Camilla Eva Comin, Giuseppe Palmieri, Antonio Cossu +13 moredoaj +1 more sourceThe HPV cellular transactivator Brn-3a can be used to predict cervical adenocarcinoma and squamous carcinoma precancer lesions in the developed and developing worlds [PDF]
, 2009 The cellular transactivator Brn-3a has previously been shown to be expressed at elevated levels in the cervix of women with squamous cell carcinoma of the cervix (SCC) and to activate the expression of HPV E6 mRNA.Ndisang, D., Ashfaq Khan, Sindos, M., Lorenzato, F., Khan, A., Latchman, David S., Singer, A., Felipe Lorenzato, David S. Latchman, Daniel Ndisang, Michael Sindos, Albert Singer +11 morecore +1 more source
