Results 21 to 30 of about 13,789 (243)

Safety and Efficacy of Tirofiban in Severe Ischemic Stroke Patients Undergoing Mechanical Thrombectomy

Journal of Cardiovascular Development and Disease, 2022
Tirofiban has recently shown encouraging efficacy and safety among acute ischemic stroke (AIS) patients with mechanical thrombectomy (MT). However, the benefits of tirofiban varied among studies depending on the patient’s condition, which was often not ...
Lingxin Cai, Tingting Wang, Aiqing Chen, Chenhan Ling, Jing Xu, Cong Qian, Gao Chen   +6 more
doaj   +2 more sources

Efficacy and Safety of Tirofiban in Clinical Patients With Acute Ischemic Stroke

Frontiers in Neurology, 2022
BackgroundIntravenous thrombolysis and endovascular thrombectomy have been approved for acute ischemic stroke (AIS). However, only a minority of patients received these treatments in China.
Bin Han, Teng Ma, Zhendong Liu, Yiqun Wu, Weiwei Tan, Shaoyang Sun, Xuemei Li, Changyan Shao, Duyong Tang, Jinping Sun, Jinping Sun, Jinping Sun   +11 more
doaj   +2 more sources

Clinical safety and possible efficacy of tirofiban in combination with intravenous thrombolysis by recombinant tissue plasminogen activator for early treatment of capsular warning syndrome (CWS)

Frontiers in Neuroscience, 2022
The purpose of this study was to assess the efficacy and safety of the combination of tirofiban with intravenous thrombolysis (IVT) in treating patients with capsular warning syndrome (CWS) who failed to respond to the treatment of intravenous ...
Yunzhu Liu, Shiyong Li, Dongdong Hao, Zhongping Zhang, Yongxin Yi, Jiayang Fang, Weizhi Lin, Min Zhang   +7 more
doaj   +2 more sources

Comparison of safety and efficacy after emergency stenting in patients exhibiting intracranial atherosclerotic stenosis associated with large-vessel occlusion with and without intravenous infusion of tirofiban [PDF]

Cardiovascular and Interventional Radiology, 2023
Purpose Intracranial rescue stent angioplasty is a bailout strategy for acute stroke patients in cases of unsuccessful endovascular thrombectomy due to underlying atherosclerotic stenosis.
Berlis, Ansgar, Ertl, Michael, Garayzade, Rana, Maurer, Christoph J., Müller, Gernot, Schiele, Stefan, Schneider, Hauke   +6 more
core   +2 more sources

Association of Tirofiban With Functional Outcomes After Thrombectomy in Acute Ischemic Stroke Due to Intracranial Atherosclerotic Disease

Neurology, 2023
Background and Objective To investigate the efficacy and safety of IV infusion of tirofiban before endovascular thrombectomy for patients with large vessel occlusion due to intracranial atherosclerotic disease.
Hongfei Sang, D. Xie, Yan Tian, Thanh N. Nguyen, J. Saver, R. Nogueira, Jun-Zuo Wu, C. Long, Zhen-Biao Tian, Zhizhou Hu, Tao Wang, Rongzong Li, Yingbing Ke, Xiurong Zhu, Daizhou Peng, Mingze Chang, Lingfei Li, J. Ruan, Deping Wu, W. Zi, Qingwu Yang, Fengli Li, Zhongming Qiu   +22 more
semanticscholar   +1 more source

Tirofiban for Stroke without Large or Medium-Sized Vessel Occlusion.

New England Journal of Medicine, 2023
BACKGROUND The effects of the glycoprotein IIb/IIIa receptor inhibitor tirofiban in patients with acute ischemic stroke but who have no evidence of complete occlusion of large or medium-sized vessels have not been extensively studied.
W. Zi, Jiaxing Song, W. Kong, Jiacheng Huang, Chang-Yu Guo, Wencheng He, Yinquan Yu, Bo Zhang, Wanjie Geng, Xiaolin Tan, Yaoyu Tian, Zongtao Liu, Minghua Cao, Daoyou Cheng, Bowen Li, Wenguo Huang, Junsheng Liu, Pengfei Wang, Zhou Yu, Hao Liang, Shuang Yang, Mingshan Tang, Wen-hua Liu, Xianjun Huang, Shugai Liu, Yufeng Tang, Youlin Wu, Linzhi Yao, Zhu Shi, Pengcheng He, Haojin Zhao, Zhuo Chen, Jun Luo, Y. Wan, Qiang Shi, Mao-Tao Wang, D. Yang, X. Chen, Fang Huang, Jin-hua Mu, Hao Li, Zhimin Li, Jingbang Zheng, Shunli Xie, Tieying Cai, Yuqi Peng, Weihua Xie, Zhongming Qiu, Chang Liu, C. Yue, Linyu Li, Yan Tian, Dahong Yang, J. Miao, Jie Yang, Jinrong Hu, R. Nogueira, Duolao Wang, J. Saver, Fengli Li, Qingwu Yang   +60 more
semanticscholar   +1 more source

Effect of Intravenous Tirofiban vs Placebo Before Endovascular Thrombectomy on Functional Outcomes in Large Vessel Occlusion Stroke: The RESCUE BT Randomized Clinical Trial.

Journal of the American Medical Association (JAMA), 2022
Importance Tirofiban is a highly selective nonpeptide antagonist of glycoprotein IIb/IIIa receptor, which reversibly inhibits platelet aggregation.
Zhongming Qiu, Fengli Li, Hongfei Sang, W. Luo, Shuai Liu, Wen-hua Liu, Zhangbao Guo, Huagang Li, Dong Sun, Wenguo Huang, Min Zhang, Min Zhang, Weipeng Dai, Peiyang Zhou, Wei Deng, Zhiming Zhou, Xianjun Huang, Bo Lei, Jinglun Li, Zhengzhou Yuan, Bo Song, J. Miao, Shudong Liu, Zhe-zhi Jin, Guoyong Zeng, Hongliang Zeng, Junjie Yuan, C. Wen, Yang Yu, Guangxiong Yuan, Jun-Zuo Wu, Chen Long, Jun Luo, Zhen-Biao Tian, C. Zheng, Zhizhou Hu, Shouchun Wang, Tao Wang, Li Qi, Rongzong Li, Y. Wan, Yingbing Ke, Youlin Wu, Xiurong Zhu, W. Kong, Jiacheng Huang, Daizhou Peng, Mingze Chang, Hanming Ge, Zhonghua Shi, Zhizhong Yan, Jie Du, Yingchun Jin, Dongsheng Ju, Chuming Huang, Yifan Hong, Tianzhu Liu, Wenlong Zhao, Jian Wang, Bo Zheng, Li Wang, Shugai Liu, Xiaojun Luo, Shiwei Luo, Xinwei Xu, Jinrong Hu, J. Pu, Shengli Chen, Yaxuan Sun, Shun‐cai Jiang, Liping Wei, Xinmin Fu, Yongjie Bai, Shunyu Yang, Wei Hu, Guling Zhang, Chen-hui Pan, Shuai Zhang, Yan Wang, W. Cao, Shi-quan Yang, Jun Zhang, F. Guo, Hongbin Wen, Jinhua Zhang, Jiaxing Song, C. Yue, Linyu Li, Deping Wu, Yan Tian, Jie Yang, M. Lu, J. Saver, R. Nogueira, W. Zi, Qingwu Yang   +95 more
semanticscholar   +1 more source

Preoperative and intraoperative tirofiban during endovascular thrombectomy in large vessel occlusion stroke due to large artery atherosclerosis. [PDF]

Eur J Neurol
Background and purpose The aim of this study is to investigate the efficacy and safety of preoperative versus intraoperative tirofiban in patients with large vessel occlusion (LVO) due to large artery atherosclerosis (LAA).
Sun Z, Huang S, Li W, Yang Y, Wu Y, Ma X, Nie X, Jin W, Liu C, Li X, Xu Y, Dong J, Liao Y, Sun B, Han W, Zhao Q, Chi H, Wang Y, Liu L, Zhang M.   +19 more
europepmc   +2 more sources

Comparison of the effect of ticagrelor combined with tirofiban versus clopidogrel combined with tirofiban on inflammation response and prognosis of patients with unstable angina pectoris in long term follow‐up

Kaohsiung Journal of Medical Sciences, 2021
To investigate the effect of ticagrelor combined with tirofiban versus clopidogrel combined with tirofiban on inflammation response and prognosis of patients with unstable angina pectoris (UA).
Li Deng, Hai‐Zhen Jia, Mao‐Chun Li, Wei Zhu   +3 more
doaj   +1 more source

Tirofiban-induced thrombocytopenia

Annals medicus, 2023
Tirofiban is a small non-peptide ligand-mimetic Glycoprotein (GP) IIb/IIIa inhibitor which can reversibly bind to the arginine-glycine-aspartic acid (RGD) recognition site of GP IIb/IIIa to prevent platelet aggregation.
Jun Wang, Dongna Zou
semanticscholar   +1 more source