Results 31 to 40 of about 77,902 (291)

教師教學過程中心流體驗之研究 The Study on the Flow Experience of the Teacher While in Teaching

open access: yesShizi Peiyu Yu Jiaoshi Zhuanye Fazhan Qikan, 2015
本研究以Csikszentmihalyi 所提出的心流體驗為要,探究教師教學過程中心流體驗之感受經歷、影響教師心流體驗要素與心流體驗對於教師教學上之助益,並對6 位教師進行深度訪談,期望對教師教學過程中心流體驗之感受有深入之瞭解。本研究歸出並非每一位教師於課堂教學時皆能深刻感受到心流體驗;班級學生秩序常規影 響教師心流體驗之感受;校長巡堂通常被視為一種干擾,不利教師心流體驗之發展;友善且資源充足之工作環境有助於教師感受心流體驗;心流體驗有助於教師教學品質之提昇 ...
方淑儀 Shu-I Fang
doaj   +1 more source

青銀世代之數位遊戲使用認知與趨避衝突:語意聯想測驗之內容分析 Cognitive Differences and ApproachAvoidance Conflict in Digital Gaming Across Generations: Content Analysis of Taiwanese Individuals’ Responses on the Word Association Test

open access: yesJournal of Research in Education Sciences
青銀世代對數位遊戲的使用動機具差異性,而數位遊戲的開發或設計往往無法為所有年齡層量身定做,例如長者對於規則太複雜、時間太緊湊的遊戲設計有負面的認知,但年輕人反而追求遊戲的效率。此外,過去探討不同世代數位遊戲設計及功能評估的研究,大多為受試者自陳、觀察和訪談方法蒐集主動意識層面的資料,較少透過語意聯想這類的結果探究。 據此,本研究欲以數位遊戲認知的語意聯想測驗(Word Association Test, WAT)蒐集多元的資料以探討世代間之異同。本研究以便利取樣招募178位不同年齡層的對象 ...
劉智淇 Chih-Chi Liu   +1 more
doaj   +1 more source

大學生健康老化多元創意教學課程之成效研究:從健康覺察到行動 Effects of Multiple-Creative Teaching Strategies in a Healthy Aging Course for College Students: From Health Self-Awareness to Action

open access: yesJournal of Research in Education Sciences, 2019
本研究運用行為改變的跨理論模式和健康自我管理計畫方法,再融入代間學習的策略發展成健康老化多元創意課程,並評量此課程的立即學習成效和延宕效果。研究對象為選修老化相關課程之大學生 35 人。本研究採質量並重的混合研究方法,運用單組前測、後測及後後測的研究設計之量化分析,以及透過課程觀察紀錄和學生反思報告之質性資料分析來記錄學習歷程與成效。研究結果發現,健康老化多元創意教學對學生健康老化知識、態度和健康行為的學習影響皆具有正面顯著的影響,且經過 1 年後,不論知識、態度或行為,其正面成效 不僅持續 ...
陳毓璟 Stephanie Yu-Ching Chen
doaj   +1 more source

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi   +26 more
wiley   +1 more source

The relationship between social media usage and loneliness among younger and older adults: the moderating effect of shyness

open access: yesBMC Psychology
Does social media alleviate or exacerbate loneliness? Past research has shown mixed results regarding the relationship between social media usage and loneliness among younger and older adults.
Ya-Ling Wang, Yi-Jia Chen, Chih-Chi Liu
doaj   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini   +10 more
wiley   +1 more source

Modeling User Participation in Facebook Live by Applying the Mediating Role of Social Presence

open access: yesInformation, 2023
The rapid development of mobile Internet technology has brought about the flourishing growth of social media live streaming. This study employs social presence theory as the primary framework to investigate the impact of Facebook Live’s features of ...
Yimin Lum, Chen-Wei Chang
doaj   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan   +10 more
wiley   +1 more source

透過社會運動學習:萬華社區大學講師陳情行動歷程之框架理論分析 Learning Through Social Movement: A Study of the Application of Framing Theory in a Petition Process Initiated by Instructors of Wanhua Community College

open access: yes臺灣教育社會學研究, 2013
本研究採質性研究方法,順著萬華社區大學(後稱社大)講師陳情行動進程,釐清講師們如何透過框架理論操作持續賦予教育局負面評鑑結果另類新意,並藉由擬訂因應策略喚起參與動機,抗議教育局評鑑不公,爭取程序正義。研究發現,社大講師參與陳情行動的主因並非公共理由,而是教育局的污名化評鑑結果與其正向認同與情感落差過大;加上教育局撤銷或接管社大耳語不斷,他校支持者又將社大運作機制結構性問題搬上檯面,更讓講師認定此事出於教育局不公,進而激發其不滿情緒和參與動力。此外,本研究也發現陳情行動的參與 ...
徐敏雄 Min-Hsiung Hsu
doaj   +1 more source

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

open access: yesMolecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim   +8 more
wiley   +1 more source

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