Results 31 to 40 of about 460,880 (412)

An Analytic Method to Determine the Optimal Time for the Induction Phase of Anesthesia [PDF]

open access: yesAxioms 12 (2023), no. 9, Art. 867, 15pp, 2023
We obtain an analytical solution for the time-optimal control problem in the induction phase of anesthesia. Our solution is shown to align numerically with the results obtained from the conventional shooting method. The induction phase of anesthesia relies on a pharmacokinetic/pharmacodynamic (PK/PD) model proposed by Bailey and Haddad in 2005 to ...
arxiv   +1 more source

Propofol EC50 for inducing loss of consciousness in patients under combined epidural-general anesthesia or general anesthesia alone: a randomized double-blind study

open access: yesFrontiers in Medicine, 2023
BackgroundCombined epidural-general anesthesia (GA + EA) has been recommended as a preferred technique for both thoracic and abdominal surgery. The epidural anesthesia on the general anesthetic (GA) requirements has not been well investigated. Therefore,
Jiangling Wang   +8 more
doaj   +1 more source

Lipid Emulsion for Treating Local Anesthetic Systemic Toxicity

open access: yesInternational Journal of Medical Sciences, 2018
Lipid emulsion has been shown to be an effective treatment for systemic toxicity induced by local anesthetics, which is reflected in case reports. A systemic review and meta-analysis confirm the efficacy of this treatment.
S. Ok, Jeong-Min Hong, S. Lee, J. Sohn
semanticscholar   +1 more source

Monosynaptic Functional Connectivity in Cerebral Cortex During Wakefulness and Under Graded Levels of Anesthesia [PDF]

open access: yes, 2012
The balance between excitation and inhibition is considered to be of significant importance for neural computation and cognitive function. Excitatory and inhibitory functional connectivity in intact cortical neuronal networks in wakefulness and graded ...
Diba, Kamran   +4 more
core   +3 more sources

Local Anesthetics [PDF]

open access: yesJournal of Industrial & Engineering Chemistry, 1920
n ...
openaire   +4 more sources

Features and mechanisms of propofol-induced protein kinase C (PKC) translocation and activation in living cells

open access: yesFrontiers in Pharmacology, 2023
Background and purpose: In this study, we aimed to elucidate the action mechanisms of propofol, particularly those underlying propofol-induced protein kinase C (PKC) translocation.Experimental approach: Various PKCs fused with green fluorescent protein ...
Soma Noguchi   +15 more
doaj   +1 more source

Local Anesthetic-Induced Neurotoxicity

open access: yesInternational Journal of Molecular Sciences, 2016
This review summarizes current knowledge concerning incidence, risk factors, and mechanisms of perioperative nerve injury, with focus on local anesthetic-induced neurotoxicity.
M. Verlinde   +5 more
semanticscholar   +1 more source

Sympathomimetic anesthetics [PDF]

open access: yesCanadian Anaesthetists’ Society Journal, 1973
The characteristic anaesthetic and other pharmacological properties of phencyclidine, ketamine, dexoxadrol and etoxadrol and the structure-activity relationship of these compounds have been described. Their possible mode of action is discussed in reference to the central depressant actions of the sympathomimetic amines.
openaire   +3 more sources

Common anesthetic molecules prefer to partition in liquid disorder phase domain in a composite multicomponent membrane [PDF]

open access: yesPhys. Rev. E 98, 012409 (2018), 2018
Despite a vast clinical application of anesthetics, the molecular level of understanding of general anesthesia is far from our reach. Using atomistic molecular dynamics simulation, we study the effects of common anesthetics: ethanol, chloroform and methanol in the fully hydrated symmetric multicomponent lipid bilayer membrane comprising of an ...
arxiv   +1 more source

L’UTILISATION DE L’HUILE DE CLOU DE GIROFLE COMME ANESTHÉSIQUE POUR LES SMOLTS DE SAUMON ATLANTIQUE (SALMO SALAR L.) ET COMPARAISON DE SES EFFETS AVEC CEUX DU 2-PHENOXYETHANOL.

open access: yesKnowledge and Management of Aquatic Ecosystems, 2002
Cette étude révèle que l’huile de clou de girofle est un bon anesthésique pour les smolts de saumon atlantique, plus performant que le 2-phénoxyéthanol car agissant pour de plus faibles concentrations.
CHANSEAU M.   +3 more
doaj   +1 more source

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