Results 31 to 40 of about 455,483 (353)

A krónikus szívelégtelenség epidemiológiája, a kezelési lehetőségek, a bisoprolol helye a terápiás palettán [PDF]

, 2013
The prevalence of chronic heart failure in Hungary is 1.6% in the adult population, but it occurs in 15-20% of subjects over 80 years of age. The base of treatment of heart failure is the blockade of the neuro-hormonal system, which includes the use of ...
Nagy, Viktor
core   +1 more source

Circulating plasma concentrations of angiotensin-converting enzyme 2 in men and women with heart failure and effects of renin–angiotensin–aldosterone inhibitors

European Heart Journal, 2020
Aims The current pandemic coronavirus SARS-CoV-2 infects a wide age group but predominantly elderly individuals, especially men and those with cardiovascular disease. Recent reports suggest an association with use of renin–angiotensin–aldosterone system (
I. Sama, Alice Ravera, B. Santema, H. van Goor, J. T. ter Maaten, J. Cleland, M. Rienstra, A. Friedrich, N. Samani, L. Ng, K. Dickstein, C. Lang, G. Filippatos, S. Anker, P. Ponikowski, M. Metra, D. V. van Veldhuisen, A. Voors   +17 more
semanticscholar   +1 more source

Isolation of Bat Sarbecoviruses, Japan

Emerging Infectious Diseases, 2022
Surveillance of bat betacoronaviruses is crucial for understanding their spillover potential. We isolated bat sarbecoviruses from Rhinolophus cornutus bats in multiple locations in Japan. These viruses grew efficiently in cells expressing R.
Shin Murakami, Tomoya Kitamura, Hiromichi Matsugo, Haruhiko Kamiki, Ken Oyabu, Wataru Sekine, Akiko Takenaka-Uema, Yuko Sakai-Tagawa, Yoshihiro Kawaoka, Taisuke Horimoto   +9 more
doaj   +1 more source

Significant correlation of angiotensin converting enzyme and glycoprotein IIIa genes polymorphisms with unexplained recurrent pregnancy loss in north of Iran [PDF]

, 2016
Background: Spontaneous abortion is considered as the most complex problem during pregnancy. Thrombophilia is resumed as a cause of recurrent pregnancy loss (RPL). Glycoprotein IIIa (GPIIIa) gene is involved in thrombosis and abortion.
Farazmandfar, T., Fazelnia, S., Hashemi-Soteh, S.M.B.   +2 more
core   +1 more source

Lethality of SARS-CoV-2 infection in K18 human angiotensin-converting enzyme 2 transgenic mice

Nature Communications, 2020
Vaccine and antiviral development against SARS-CoV-2 infection or COVID-19 disease would benefit from validated small animal models. Here, we show that transgenic mice expressing human angiotensin-converting enzyme 2 (hACE2) by the human cytokeratin 18 ...
Fatai S. Oladunni, Jun-Gyu Park, P. Pino, O. Gonzalez, A. Akhter, Anna Allué-Guardia, Angélica M. Olmo-Fontánez, S. Gautam, Andreu Garcia-Vilanova, C. Ye, Kevin Chiem, Colwyn A. Headley, V. Dwivedi, Laura M. Parodi, K. Alfson, Hilary M Staples, A. Schami, J. García, Alison Whigham, R. N. Platt, M. Gazi, Jesse C Martinez, Colin Chuba, S. Earley, Oscar H Rodriguez, S. Mdaki, Katrina N. Kavelish, Renee Escalona, C. Hallam, Corbett Christie, J. Patterson, T. Anderson, R. Carrion, E. Dick, Shannan Hall-Ursone, L. Schlesinger, X. Alvarez, D. Kaushal, L. Giavedoni, J. Turner, L. Martínez-Sobrido, J. Torrelles   +41 more
semanticscholar   +1 more source

Antecedent Administration of Angiotensin‐Converting Enzyme Inhibitors or Angiotensin II Receptor Antagonists and Survival After Hospitalization for COVID‐19 Syndrome

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) utilizes the angiotensin‐converting enzyme‐2 (ACE‐2) receptor to enter human cells.
Alberto Palazzuoli, Massimo Mancone, Gaetano M. De Ferrari, Giovanni Forleo, Gioel G. Secco, Gaetano M. Ruocco, Fabrizio D'Ascenzo, Silvia Monticone, Anita Paggi, Marco Vicenzi, Anna G. Palazzo, Maurizio Landolina, Erika Taravelli, Guido Tavazzi, Francesco Blasi, Fabio Infusino, Francesco Fedele, Francesco G. De Rosa, Michael Emmett, Jeffrey M. Schussler, Kristen M. Tecson, Peter A. McCullough   +21 more
doaj   +1 more source

Supplementary data for “Comparisons of Staphylococcus aureus infection and other outcomes between users of angiotensin-converting-enzyme inhibitors and angiotensin II receptor blockers: lessons for COVID-19 from a nationwide cohort study” [PDF]

, 2020
Additional information regarding study design, baseline cohort characteristics, and results of sensitivity ...
Bidulka, Patrick, Iwagami, Masao, Tomlinson, Laurie A., Wong, Angel Y.S.   +3 more
core   +1 more source

Association of Use of Angiotensin-Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers With Testing Positive for Coronavirus Disease 2019 (COVID-19).

JAMA cardiology, 2020
Importance The role of angiotensin-converting enzyme inhibitors (ACEI) and angiotensin II receptor blockers (ARB) in the setting of the coronavirus disease 2019 (COVID-19) pandemic is hotly debated.
N. Mehta, A. Kalra, A. Nowacki, Scott Anjewierden, Zheyi Han, Pavan Bhat, A. Carmona-Rubio, M. Jacob, G. Procop, S. Harrington, A. Milinovich, L. Svensson, L. Jehi, James B. Young, M. Chung   +14 more
semanticscholar   +1 more source

Immunohistochemical expression of intrarenal renin angiotensin system components in response to tempol in rats fed a high salt diet [PDF]

, 2017
AIM:To determine the effect of tempol in normal rats fed high salt on arterial pressure and the balance between antagonist components of the renal renin-angiotensin system.METHODS:Sprague-Dawley rats were fed with 8% NaCl high-salt (HS) or 0.4% NaCl ...
Cao, Gabriel Fernando, Choi, Marcelo Roberto, Della Penna, Silvana Lorena, Fernandez, Belisario Enrique, Gorzalczany, Susana Beatriz, Kouyoumdzian, Nicolás Martín, Roson, Maria Ines, Toblli, Jorge Eduardo   +7 more
core   +1 more source

Association of Angiotensin-Converting Enzyme Inhibitor or Angiotensin Receptor Blocker Use With COVID-19 Diagnosis and Mortality.

Journal of the American Medical Association (JAMA), 2020
Importance It has been hypothesized that angiotensin-converting enzyme inhibitors (ACEIs)/angiotensin receptor blockers (ARBs) may make patients more susceptible to coronavirus disease 2019 (COVID-19) and to worse outcomes through upregulation of the ...
E. Fosbøl, J. Butt, L. Østergaard, C. Andersson, C. Selmer, K. Kragholm, M. Schou, M. Phelps, G. Gislason, T. Gerds, C. Torp‐Pedersen, L. Køber   +11 more
semanticscholar   +1 more source