Results 31 to 40 of about 106,556 (213)

A Well-Conserved Archaeal B-Family Polymerase Functions as an Extender in Translesion Synthesis

mBio, 2022
B-family DNA polymerases (PolBs) of different groups are widespread in Archaea, and different PolBs often coexist in the same organism. Many of these PolB enzymes remain to be investigated.
Xu Feng, Baochang Zhang, Zhe Gao, Ruyi Xu, Xiaotong Liu, Sonoko Ishino, Mingxia Feng, Yulong Shen, Yoshizumi Ishino, Qunxin She   +9 more
doaj   +1 more source

Heavily Armed Ancestors: CRISPR Immunity and Applications in Archaea with a Comparative Analysis of CRISPR Types in Sulfolobales

Biomolecules, 2020
Prokaryotes are constantly coping with attacks by viruses in their natural environments and therefore have evolved an impressive array of defense systems.
Isabelle Anna Zink, Erika Wimmer, Christa Schleper   +2 more
doaj   +1 more source

Enzymatic Switching Between Archaeal DNA Polymerases Facilitates Abasic Site Bypass

Frontiers in Microbiology, 2021
Abasic sites are among the most abundant DNA lesions encountered by cells. Their replication requires actions of specialized DNA polymerases. Herein, two archaeal specialized DNA polymerases were examined for their capability to perform translesion DNA ...
Xu Feng, Baochang Zhang, Ruyi Xu, Zhe Gao, Xiaotong Liu, Guanhua Yuan, Sonoko Ishino, Mingxia Feng, Yulong Shen, Yoshizumi Ishino, Qunxin She   +10 more
doaj   +1 more source

CRISPR-mediated gene silencing reveals involvement of the archaeal S-layer in cell division and virus infection

Nature Communications, 2019
The S-layer is a proteinaceous envelope often found in bacterial and archaeal cells. Here, the authors use CRISPR-based technology to silence slaB, encoding the S-layer membrane anchor, to show that an intact S-layer is important for cell division and ...
Isabelle Anna Zink, Kevin Pfeifer, Erika Wimmer, Uwe B. Sleytr, Bernhard Schuster, Christa Schleper   +5 more
doaj   +1 more source

Roadmap for naming uncultivated Archaea and Bacteria

Nature Microbiology, 2020
The assembly of single-amplified genomes (SAGs) and metagenome-assembled genomes (MAGs) has led to a surge in genome-based discoveries of members affiliated with Archaea and Bacteria, bringing with it a need to develop guidelines for nomenclature of ...
A. Murray, J. Freudenstein, S. Gribaldo, R. Hatzenpichler, P. Hugenholtz, P. Kämpfer, K. Konstantinidis, C. Lane, R. Papke, Donovan H. Parks, R. Rosselló-Móra, M. Stott, I. Sutcliffe, J. C. Thrash, S. Venter, W. Whitman, S. Acinas, R. Amann, Karthik Anantharaman, J. Armengaud, B. Baker, R. Barco, H. Bode, E. Boyd, Carrie Brady, P. Carini, P. Chain, D. Colman, Kristen M. DeAngelis, Maria Asuncion de los Rios, Paulina Estrada-de los Santos, C. Dunlap, J. Eisen, D. Emerson, Thijs J. G. Ettema, D. Eveillard, P. Girguis, U. Hentschel, J. Hollibaugh, L. Hug, W. Inskeep, E. Ivanova, H. Klenk, Wenjun Li, K. Lloyd, F. Löffler, T. Makhalanyane, D. Moser, T. Nunoura, M. Palmer, V. Parro, C. Pedrós-Alió, Alexander J. Probst, T. H. Smits, A. D. Steen, E. Steenkamp, A. Spang, F. Stewart, J. Tiedje, P. Vandamme, M. Wagner, Feng-Ping Wang, B. Hedlund, A. Reysenbach   +63 more
semanticscholar   +1 more source

Structure and in situ organisation of the Pyrococcus furiosus archaellum machinery

eLife, 2017
The archaellum is the macromolecular machinery that Archaea use for propulsion or surface adhesion, enabling them to proliferate and invade new territories.
Bertram Daum, Janet Vonck, Annett Bellack, Paushali Chaudhury, Robert Reichelt, Sonja-Verena Albers, Reinhard Rachel, Werner Kühlbrandt   +7 more
doaj   +1 more source

Analysis of Cell–Cell Bridges in Haloferax volcanii Using Electron Cryo-Tomography Reveal a Continuous Cytoplasm and S-Layer

Frontiers in Microbiology, 2021
Halophilic archaea have been proposed to exchange DNA and proteins using a fusion-based mating mechanism. Scanning electron microscopy previously suggested that mating involves an intermediate state, where cells are connected by an intercellular bridge ...
Shamphavi Sivabalasarma, Shamphavi Sivabalasarma, Hanna Wetzel, Phillip Nußbaum, Chris van der Does, Morgan Beeby, Sonja-Verena Albers, Sonja-Verena Albers   +7 more
doaj   +1 more source

Phylogenomics of 10,575 genomes reveals evolutionary proximity between domains Bacteria and Archaea

Nature Communications, 2019
Rapid growth of genome data provides opportunities for updating microbial evolutionary relationships, but this is challenged by the discordant evolution of individual genes.
Qiyun Zhu, U. Mai, W. Pfeiffer, Stefan Janssen, F. Asnicar, J. Sanders, P. Belda-Ferre, Gabriel A. Al-Ghalith, Evguenia Kopylova, Daniel McDonald, T. Kosciólek, John B. Yin, Shi Huang, Nimaichand Salam, Jian-Yu Jiao, Zijun Wu, Z. Xu, Kalen Cantrell, Yimeng Yang, Erfan Sayyari, M. Rabiee, James T. Morton, S. Podell, D. Knights, Wenjun Li, C. Huttenhower, N. Segata, L. Smarr, S. Mirarab, R. Knight   +29 more
semanticscholar   +1 more source

Altered Gut Archaea Composition and Interaction with Bacteria are Associated with Colorectal Cancer.

Gastroenterology, 2020
BACKGROUND & AIMS Changes in the intestinal microbiota have been associated with development and progression of colorectal cancer (CRC). Archaea are stable components of the microbiota, but little is known about their composition or contribution to ...
O. Coker, W. Wu, S. Wong, J. Sung, Jun Yu   +4 more
semanticscholar   +1 more source

Cyclic nucleotides in archaea: Cyclic di‐AMP in the archaeon Haloferax volcanii and its putative role

MicrobiologyOpen, 2019
The role of cyclic nucleotides as second messengers for intracellular signal transduction has been well described in bacteria. One recently discovered bacterial second messenger is cyclic di‐adenylate monophosphate (c‐di‐AMP), which has been demonstrated
Frank Braun, Laura Thomalla, Chris van derDoes, Tessa E. F. Quax, Thorsten Allers, Volkhard Kaever, Sonja‐Verena Albers   +6 more
doaj   +1 more source