Results 31 to 40 of about 622,830 (342)

“Jnking” atherosclerosis [PDF]

Cellular and Molecular Life Sciences, 2005
ISSN:1420 ...
Sumara, G., Belwal, M., Ricci, R.
openaire   +3 more sources

Hypertriglyceridemia and atherosclerosis [PDF]

Lipids in Health and Disease, 2017
Atherosclerotic cardiovascular disease (ASCVD) is the leading cause of death and it has been confirmed that increased low density lipoprotein cholesterol (LDL-C) is an independent risk factor for atherosclerosis. Recently, the increasing evidence has showed that hypertriglyceridemia is associated with incremental ASCVD risk.
Jia Peng, Fei Luo, Guiyun Ruan, Ran Peng, Xiangping Li   +4 more
openaire   +4 more sources

The Diabetes Mellitus–Atherosclerosis Connection: The Role of Lipid and Glucose Metabolism and Chronic Inflammation

International Journal of Molecular Sciences, 2020
Diabetes mellitus comprises a group of carbohydrate metabolism disorders that share a common main feature of chronic hyperglycemia that results from defects of insulin secretion, insulin action, or both.
A. Poznyak, A. Grechko, P. Poggio, V. Myasoedova, V. Alfieri, A. Orekhov   +5 more
semanticscholar   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

Inflammation and Atherosclerosis [PDF]

European Journal of Vascular and Endovascular Surgery, 2006
The aim of this article is to discuss the role of inflammation in atherosclerosis.An initial chemical, mechanical or immunological insult induces endothelial dysfunction. This triggers a cascade of inflammatory reactions, in which monocytes, macrophages, T lymphocytes and vascular smooth muscle cells participate. Leukocyte adhesion molecules, cytokines,
John D. Kakisis, Dimitrios Dimitroulis, E. Kaperonis, Christos D. Liapis, Vassilios Papavassiliou   +4 more
openaire   +2 more sources

Inflammation, Atherosclerosis and Coronary Artery Disease

Clinical Medicine Insights: Cardiology, 2014
Article types include original clinical and basic research articles, case reports, commentaries, meeting reports, methodology, perspectives. Research into inflammation, atherosclerosis and coronary artery disease, including observational studies ...
Y. Momiyama, H. Adachi, D. Fairweather, N. Ishizaka, Emi Saita   +4 more
semanticscholar   +1 more source

Treatment of atherosclerosis by macrophage-biomimetic nanoparticles via targeted pharmacotherapy and sequestration of proinflammatory cytokines

Nature Communications, 2020
Vascular disease remains the leading cause of death and disability, the etiology of which often involves atherosclerosis. The current treatment of atherosclerosis by pharmacotherapy has limited therapeutic efficacy.
Cheng Gao, Qiaoxian Huang, Conghui Liu, Cheryl H. T. Kwong, Ludan Yue, J. Wan, S. M. Lee, Ruibing Wang   +7 more
semanticscholar   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Inflammation in atherosclerosis [PDF]

Nature, 2002
Experimental work has elucidated molecular and cellular pathways of inflammation that promote atherosclerosis. Unraveling the roles of cytokines as inflammatory messengers provided a mechanism whereby risk factors for atherosclerosis can alter arterial biology, and produce a systemic milieu that favors atherothrombotic events.
openaire   +4 more sources

Lymphocytes in atherosclerosis [PDF]

Clinica Chimica Acta, 2012
It is well established that atherosclerosis is caused by an inflammatory process in the arterial intima. However, it is only in recent years that it has become clear that this inflammation is modulated by immune responses against plaque antigens. These antigens are primarily believed to be modified self-antigens such as oxidized LDL.
Wigren, Maria, Nilsson, Jan, Kolbus, Daniel   +2 more
openaire   +5 more sources