Results 31 to 40 of about 807,354 (326)

Mesenchymal stem cells: A novel treatment option for primary sclerosing cholangitis

Cell Biology International, Volume 47, Issue 2, Page 467-479, February 2023., 2023
Abstract Primary sclerosing cholangitis (PSC) is a progressive liver disease for which there is no effective therapy. Hepatocytes and cholangiocytes from a PSC patient were cocultured with mesenchymal stem cells (MSCs) to assess in vitro change. A single patient with progressive PSC was treated with 150 million MSCs via direct injection into the common
Amy L. Lightner, Neda Dadgar, Anil Vaidya, Robert Simon, Clifton Fulmer, Hassan Siddiki, K. V. Narayanan Menon, Peter Liu, R. Matthew Walsh   +8 more
wiley   +1 more source

Tongxinluo enhances the effect of atorvastatin on the treatment of atherosclerosis with chronic obstructive pulmonary disease by maintaining the pulmonary microvascular barrier

Food Science &Nutrition, Volume 11, Issue 1, Page 390-407, January 2023., 2023
COPD aggravates AS, possibly through the destruction of pulmonary microvascular barrier function; thus, lung inflammation triggers systemic inflammation. In treating COPD with AS, TXL enhances the antiatherosclerotic effect of Ato, protecting the pulmonary microvascular barrier.
Xiangnan Kuang, Yafen Wang, Shiqiao Liu, Liping Chang, Yujie Yin, Zhen Li, Yi Liu, Wenyan Li, Yunlong Hou, Hongtao Wang, Junqing Liang, Zhenhua Jia   +11 more
wiley   +1 more source

Genetic predisposition to porto‐sinusoidal vascular disorder: A functional genomic‐based, multigenerational family study

Hepatology, EarlyView., 2022
A deleterious variant of FCHSD1 results in mTOR pathway overactivation and may cause porto‐sinusoidal vascular disorder (PSVD). The pedigree of the family demonstrated an autosomal dominant disease with variable expressivity. Whole‐genome sequencing and Sanger sequencing both validated the existence of the FCHSD1 variant and the heterozygosity of c ...
Jingxuan Shan, André Megarbane, Aziz Chouchane, Deepak Karthik, Ramzi Temanni, Atilio Reyes Romero, Huiying Hua, Chun Pan, Xixi Chen, Murugan Subramanian, Chadi Saad, Hamdi Mbarek, Cybel Mehawej, Eliane Chouery, Sirin W. Abuaqel, Alexander Dömling, Sami Remadi, Cesar Yaghi, Pu Li, Lotfi Chouchane   +19 more
wiley   +1 more source

Enabling modernisation, marginalising alternatives? Kenya's agricultural policy and smallholders

Journal of International Development, Volume 35, Issue 1, Page 3-20, January 2023., 2023
Abstract To address intensifying social and environmental challenges, development policy must learn from inclusions and exclusions of past discourses. We analyse Kenya's post‐colonial agricultural policy discourse. Our analysis reveals a near‐exclusive focus on the promotion of agricultural modernisation based on industrial farm inputs, a bureaucratic ...
Fredrick Ajwang, Saurabh Arora, Joanes Atela, Joel Onyango, Mohammad Kyari   +4 more
wiley   +1 more source

Comparison of 2D and 4D Flow MRI in Neonates Without General Anesthesia

Journal of Magnetic Resonance Imaging, Volume 57, Issue 1, Page 71-82, January 2023., 2023
Background Neonates with critical congenital heart disease require early intervention. Four‐dimensional (4D) flow may facilitate surgical planning and improve outcome, but accuracy and precision in neonates are unknown. Purpose To 1) validate two‐dimensional (2D) and 4D flow MRI in a phantom and investigate the effect of spatial and temporal resolution;
Pia Sjöberg, Erik Hedström, Katrin Fricke, Petter Frieberg, Constance G Weismann, Petru Liuba, Marcus Carlsson, Johannes Töger   +7 more
wiley   +1 more source

Pigment Epithelium–Derived Factor Increases Native Collateral Blood Flow to Improve Cardiac Function and Induce Ventricular Remodeling After Acute Myocardial Infarction

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background We previously found that the structural defects of the coronary collateral microcirculation reserve (CCMR) prevent these preformed collateral vessels from continuously delivering the native collateral blood and supporting the ischemic ...
Xiucheng Liu, Zhiwei Liu, Jiali Chen, Lidong Zhu, Hao Zhang, Xiaoyu Quan, Yanliang Yuan, Haoran Miao, Bing Huang, Hongyan Dong, Zhongming Zhang   +10 more
doaj   +1 more source

Predictors and Prognostic Implications of Well-Matured Coronary Collateral Circulation in Patients with a Chronic Total Occlusion (CTO).

International Heart Journal, 2020
The predictors and prognostic implications of well-matured collaterals in those with a chronic total occlusion (CTO) are unknown. We sought to identify the determinants of collateral maturation and to determine its effects on procedural outcomes and ...
U. Allahwala, K. Kott, A. Bland, M. Ward, R. Bhindi   +4 more
semanticscholar   +1 more source

Collateral circulation in the obstruction of the superior vena cava flow

Annals of Medicine, 2021
Introduction By means of virtual reconstructions obtained from the data provided by the different Multislice Computed Venotomographies (MCVT) [1--3] performed in our institution during the period from 2015 to date, a total of 14 patients with different ...
J. Ovelar, J. Cédola, J. Merino
doaj   +1 more source

Impacts of Rapid Recanalization and Collateral Circulation on Clinical Outcome after Intraarterial Thrombolysis [PDF]

Journal of Stroke, 2015
Background and PurposeRapid recanalization might improve clinical outcomes after intraarterial thrombolysis (IAT) for acute ischemic stroke patients with collateral circulation. We determined whether rapid recanalization and collateral circulation affect
Hye Seon Jeong, Hyon-Jo Kwon, Hee-Jung Song, Hyeon-Song Koh, Yong Soo Kim, Ju Hun Lee, Jee Eun Shin, Suk Hoon Lee, Jei Kim   +8 more
doaj   +1 more source

A Brief Etymology of the Collateral Circulation [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2014
It is well known that the protective capacity of the collateral circulation falls short in many individuals with ischemic disease of the heart, brain, and lower extremities. In the past 15 years, opportunities created by molecular and genetic tools, together with disappointing outcomes in many angiogenic trials, have led to a significant increase in ...
Faber, J.E., Chilian, W.M., Deindl, E., van Royen, N., Simons, M.   +4 more
openaire   +4 more sources