Results 1 to 10 of about 235,161 (308)

Repositioning of clinically approved drug Bazi Bushen capsule for treatment of Aizheimer's disease using network pharmacology approach and in vitro experimental validation

open access: yesHeliyon, 2023
Aims: To explore the new indications and key mechanism of Bazi Bushen capsule (BZBS) by network pharmacology and in vitro experiment. Methods: The ingredients library of BZBS was constructed by retrieving multiple TCM databases.
Tongxing Wang   +11 more
doaj   +1 more source

The Collateral Directive and Financial Collateral: Ownership of, or entitlement to, collateral? [PDF]

open access: yesEuropean Property Law Journal, 2021
Abstract It is controversial if incorporeal moveables (or choses in action) can be the object of property rights. The Collateral Directive arguably attempts to take the middle-ground in this debate. It acknowledges that a person may have either ‘full ownership of’, or 'full entitlement' to, financial collateral, which are conceptualised
openaire   +1 more source

Potential Utility of Natural Products against Oxidative Stress in Animal Models of Multiple Sclerosis

open access: yesAntioxidants, 2022
Multiple sclerosis (MS) is an autoimmune-mediated degenerative disease of the central nervous system (CNS) characterized by immune cell infiltration, demyelination and axonal injury.
Zheng Zha   +4 more
doaj   +1 more source

Magnetic Resonance Imaging Investigation of Neuroplasticity After Ischemic Stroke in Tetramethylpyrazine-Treated Rats

open access: yesFrontiers in Pharmacology, 2022
Ischemic stroke elicits white matter injury typically signed by axonal disintegration and demyelination; thus, the development of white matter reorganization is needed. 2,3,5,6-Tetramethylpyrazine (TMP) is widely used to treat ischemic stroke. This study
Xue-Feng Feng   +18 more
doaj   +1 more source

Effect of Neurorepair for Motor Functional Recovery Enhanced by Total Saponins From Trillium tschonoskii Maxim. Treatment in a Rat Model of Focal Ischemia

open access: yesFrontiers in Pharmacology, 2021
Trillium tschonoskii Maxim. (TTM), is a perennial herb from Liliaceae, that has been widely used as a traditional Chinese medicine treating cephalgia and traumatic hemorrhage.
Le Yang   +20 more
doaj   +1 more source

Effect and Mechanism of Catalpol on Remyelination via Regulation of the NOTCH1 Signaling Pathway

open access: yesFrontiers in Pharmacology, 2021
Promoting the differentiation of oligodendrocyte precursor cells (OPCs) is important for fostering remyelination in multiple sclerosis. Catalpol has the potential to promote remyelination and exert neuroprotective effects, but its specific mechanism is ...
Yaqin Sun   +6 more
doaj   +1 more source

Determinants of Collateral [PDF]

open access: yesJournal of Financial Economics, 2004
This paper draws upon the theory of contracting under asymmetric information to postulate and test several hypotheses concerning the relationship between the use and amount of collateral in financial loans to firms, the risk profile of the borrower, business cycle and monetary conditions of the economy, strength of the lending relation between borrower
Jesus Saurina Salas   +2 more
openaire   +1 more source

Digital Collateral

open access: yesThe Quarterly Journal of Economics, 2021
Abstract A new form of secured lending using “digital collateral” has recently emerged, most prominently in low- and middle-income countries. Digital collateral relies on lockout technology, which allows the lender to temporarily disable the flow value of the collateral to the borrower without physically repossessing it.
Gertler, Paul   +2 more
openaire   +4 more sources

Tetramethylpyrazine promotes stroke recovery by inducing the restoration of neurovascular unit and transformation of A1/A2 reactive astrocytes

open access: yesFrontiers in Cellular Neuroscience, 2023
2,3,5,6-Tetramethylpyrazine (TMP) as an active ingredient extracted from a traditional Chinese herbal medicine Ligusticum chuanxiong Hort. has been proved to penetrate blood-brain barrier (BBB) and show neuroprotective effects on cerebral ischemia ...
Xue-feng Feng   +16 more
doaj   +1 more source

Collateral pricing☆ [PDF]

open access: yesJournal of Financial Economics, 2009
We examine how collateral affects the cost of debt capital. Theories based on borrower moral hazard and limited pledgeable income predict that collateral increases the availability of credit and reduces its price. Testing these theories is complicated by the very selection problem which they imply: creditors will demand collateral precisely from those ...
Benmelech, Efraim, Bergman, Nittai
openaire   +4 more sources

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