Results 31 to 40 of about 1,687,854 (353)

Information homeostasis as a fundamental principle governing the cell division and death [PDF]

open access: yes, 2011
To express genetic information with minimal error is one of the key functions of a cell. Here we propose an information theory based phenomenological model for the expression of genetic information.
Arvind Kumar, Harinder P. Singh
core   +3 more sources

SETD4 Confers Cancer Stem Cell Chemoresistance in Nonsmall Cell Lung Cancer Patients via the Epigenetic Regulation of Cellular Quiescence

open access: yesStem Cells International, 2023
Increasing evidence indicates that quiescent cancer stem cells (CSCs) are a root cause of chemoresistance. SET domain-containing protein 4 (SETD4) epigenetically regulates cell quiescence in breast cancer stem cells (BCSCs), and SETD4-positive BCSCs are ...
Yuehong Wang   +6 more
doaj   +1 more source

Role of homeostasis in learning sparse representations

open access: yes, 2010
Neurons in the input layer of primary visual cortex in primates develop edge-like receptive fields. One approach to understanding the emergence of this response is to state that neural activity has to efficiently represent sensory data with respect to ...
Baudot P.   +13 more
core   +4 more sources

Cell Growth and Size Homeostasis in Silico [PDF]

open access: yes, 2013
Cell growth in size is a complex process coordinated by intrinsic and environmental signals. In a recent work [Tzur et al., Science, 2009, 325:167-171], size distributions in an exponentially growing population of mammalian cells were used to infer the ...
Hu, Yucheng, Zhu, Tianqi
core   +2 more sources

The plant alkaloid tetrandrine inhibits metastasis via autophagy-dependent Wnt/β-catenin and metastatic tumor antigen 1 signaling in human liver cancer cells

open access: yesJournal of Experimental & Clinical Cancer Research, 2018
Background Tetrandrine is a bisbenzylisoquinoline alkaloid isolated from the Chinese medicinal herb Stephania tetrandra S. Moore. We previously demonstrated that tetrandrine exhibits potent antitumor effects in many types of cancer cells.
Zhenxing Zhang   +4 more
doaj   +1 more source

Conserved and Noncanonical Activities of Two Histone H3K36 Methyltransferases Required for Insect-Pathogenic Lifestyle of Beauveria bassiana

open access: yesJournal of Fungi, 2021
Set2 and Ash1 are histone methyltransferases (KMTs) in the KMT3 family normally used to catalyze methylation of histone H3K36 (H3K36me) but remain unexplored in fungal insect pathogens.
Kang Ren   +3 more
doaj   +1 more source

Systemic tryptophan homeostasis

open access: yesFrontiers in Molecular Biosciences, 2022
Tryptophan is an essential amino acid, which is not only a building block for protein synthesis, but also a precursor for the biosynthesis of co-enzymes and neuromodulators, such as NAD/NADP(H), kynurenic acid, melatonin and serotonin. It also plays a role in immune homeostasis, as local tryptophan catabolism impairs T-lymphocyte mediated immunity ...
Simon Klaessens   +9 more
openaire   +4 more sources

CaMKII-dependent regulation of cardiac Na(+) homeostasis. [PDF]

open access: yes, 2014
Na(+) homeostasis is a key regulator of cardiac excitation and contraction. The cardiac voltage-gated Na(+) channel, NaV1.5, critically controls cell excitability, and altered channel gating has been implicated in both inherited and acquired arrhythmias.
Grandi, Eleonora, Herren, Anthony W
core   +2 more sources

Homeostasis and Narcolepsy [PDF]

open access: yesSleep, 1994
Narcolepsy is characterized by irresistible daytime sleep episodes and cataplectic attacks. Because of the finding of an ultradian rhythmicity of slow-wave sleep in narcolepsy, an alteration of nonrapid eye movement sleep homeostatic regulation has been hypothesized to explain the impairment of the sleep-wakefulness cycle. This hypothesis was tested by
L Nobile   +3 more
openaire   +2 more sources

Hepcidin and iron homeostasis during pregnancy. [PDF]

open access: yes, 2014
Hepcidin is the master regulator of systemic iron bioavailability in humans. This review examines primary research articles that assessed hepcidin during pregnancy and postpartum and report its relationship to maternal and infant iron status and birth ...
Cadwell, Brooke   +4 more
core   +1 more source

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