Results 31 to 40 of about 182,946 (270)

Semiautomated glycoproteomics data analysis workflow for maximized glycopeptide identification and reliable quantification

open access: yesBeilstein Journal of Organic Chemistry, 2020
Glycoproteomic data are often very complex, reflecting the high structural diversity of peptide and glycan portions. The use of glycopeptide-centered glycoproteomics by mass spectrometry is rapidly evolving in many research areas, leading to a demand in ...
Steffen Lippold   +6 more
doaj   +1 more source

Immune phenotype is differentially affected by changing the type of bovine respiratory disease vaccine administered at revaccination in beef heifers

open access: yesFrontiers in Veterinary Science, 2023
During preconditioning, modified-live vaccines are frequently administered to beef calves before weaning. In this study, we began to characterize the immune phenotype of calves that received a modified-live vaccination at 3–4 months of age and then ...
Cassidy Reddout   +5 more
doaj   +1 more source

TFPI-2 Protects Against Gram-Negative Bacterial Infection

open access: yesFrontiers in Immunology, 2018
Tissue factor pathway inhibitor-2 (TFPI-2) has previously been characterized as an endogenous anticoagulant. TFPI-2 is expressed in the vast majority of cells, mainly secreted into the extracellular matrix.
Mohamad N. Ali   +12 more
doaj   +1 more source

SPECIFIC IMMUNOGLOBULINS FOR INTRAVENOUS INJECTION IN PEDIATRIC PRACTICES

open access: yesПедиатрическая фармакология, 2007
The article presents information on the protective and therapeutic efficiency of specific immunoglobulins for intravenous injection. The author gives a characteristics and provides regimes of medication dosage of specific immunoglobulins for intravenous ...
A.L. Zaplatnikov
doaj   +2 more sources

Correlation of immunostaining findings with demographic data and variables of Oxford classification in IgA nephropath [PDF]

open access: yesJournal of Nephropathology, 2013
Background: Oxford classification for IgA nephropathy (IgAN) did not include pattern of immunostaining in the analysis. Objective: The aim of this study is to determine the potential correlation between the immunostaining data and morphologic variables ...
Hamid Nasri   +7 more
doaj   +1 more source

Lack of evidence for a substantial rate of templated mutagenesis in B cell diversification [PDF]

open access: yesarXiv, 2020
B cell receptor sequences diversify through mutations introduced by purpose-built cellular machinery. A recent paper has concluded that a "templated mutagenesis" process is a major contributor to somatic hypermutation, and therefore immunoglobulin diversification, in mice and humans.
arxiv  

FoxO1 signaling in B cell malignancies and its therapeutic targeting

open access: yesFEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac   +3 more
wiley   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

Diagnostic Accuracy of Quick Stick for Identifying Traumatic Patients in Need of Tetanus Prophylaxis; a Cross-sectional Study

open access: yesArchives of Academic Emergency Medicine, 2017
Introduction: Based on the existing studies, measuring serum level of immunoglobulin for making decisions regarding prescription of tetanus prophylaxis seems logical and cost effective.
Iraj Golikhatir   +6 more
doaj   +1 more source

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